Evaluation of adverse drug reaction formatting in drug information mobile phone applications

Objective:To evaluate the differences in presentation (formatting) of adverse drug reaction (ADR) information within drug monographs in commonly used drug information (DI) mobile device applications.Methods:A cross-sectional analysis of ADR formatting of twenty commonly prescribed oral medications within seven DI mobile applications was performed. Databases were assessed for ADR information, including presence of placebo comparisons, severity of ADR, onset of ADR, formatting of ADRs in percentile (quantitative) format or qualitative format, whether references were used to cite information, and whether ADRs are grouped by organ system. Data was collected by two study investigators and discrepancies were resolved via consensus.Results:The seven DI mobile applications varied significantly on every analyzed ADR variable with the exception of ADR onset, which was absent in all databases. Significant differences were found for variables known to impact clinical judgment such as placebo comparisons and qualitative versus quantitative formatting. Placebo comparisons were most common among monographs in Lexicomp (30%) but were absent among monographs within other applications. Quantitative information was commonly used in most databases but was absent in Epocrates. Qualitative formatting was present in all Epocrates and Micromedex applications but absent in the majority of other applications. Substantial variations were also found in severity and grouping information.Conclusion:Substantial variation in ADR formatting exists among the most common DI mobile applications. These differences may translate into alternative interpretations of medical information and thus impact clinical judgment. Health care librarians and clinicians should consider ADR formatting when choosing between DI applications.     

高校图书馆的制度管理与人文关怀

高校图书馆管理工作是一项具有较强科学性的系统工程。为读者提供高效优质的服务是图书馆的基本工作目标。在健全规章制度的同时,人本理念、人文关怀是高校图书馆在提高服务质量过程中所面临的一个新课题。本文从制度的制定、落实和人文服务环境的营造两个方面略作探究,以求教于同仁。     

加强政府履责监督 推进惩防体系建设

责任政府是指积极履行法定义务和职责、积极回应民众的社会的基本要求,并能自觉承担政治、法律和道义责任的政府.[1]文章对食品安全的履责监督、安全生产的履责监督进行了研究,并将研究成果应用到政府部门的责任监督过程中,利用现代化的科技手段,以制度为保障,实现了政府部门及人员以"分责全方位、知责全覆盖、履责全到位、问责全过程、负责全落实"为主要内容的"五责"监督体系,从而建立起纵向到底、横向到边的网格化监管机制,实现了人为监督向网络监督、静态监督向动态监督、事后监督向过程监督的转变,取得了良好效果.     

基于ERG理论的异构信息系统知识创新激励机制研究

异构信息系统集成知识创新,一方面需要项目各方积极参与,另一方面面临着主体积极性障碍,构建知识创新激励机制成为关键问题。现有的知识创新激励机制强调了外部激励的作用,但忽略了内源性动机的影响。基于企业需求的多样性、层次性以及受挫—倒退性,引入ERG理论,建立知识创新ERG模型,分析需求层次的相互关系并细化各层次需求,以从内源性动机的视角构建知识创新激励机制。最后介绍这一机制在实践中的应用。     

物理学实验教学示范中心的建设与实践

介绍了对管理机制、教学体系、师资队伍、硬件和软件建设等方面进行的改革与探索,阐述了物理实验教学示范中心的建设理念以及中心的建设特色,并通过实践,提高了实验教学质量,培养了优秀的人才。     

我国海洋体育旅游安全管理体系研究 ——基于12395平台的模型构建

近年来中国海洋体育旅游发展迅速,但是其客观存在的风险因素和安全管理的结构性缺陷直接影响到整个产业的良性发展.从管理学角度出发,通过对影响安全的各种因素进行分析,对现有的行政管理体制和社会资源进行梳理整合,提出在12395的平台上构建海洋体育旅游安全管理体系的构想,并对其运营管理路径进行设计,以促进海洋体育旅游产业安全有序发展.     

A scale-based approach to interdisciplinary research and expertise in sports

After more than 20 years since the introduction of ecological and dynamical approaches in sports research, their promising opportunity for interdisciplinary research has not been fulfilled yet. The complexity of the research process and the theoretical and empirical difficulties associated with an integrated ecological-dynamical approach have been the major factors hindering the generalisation of interdisciplinary projects in sports sciences. To facilitate this generalisation, we integrate the major concepts from the ecological and dynamical approaches to study behaviour as a multi-scale process. Our integration gravitates around the distinction between functional (ecological) and execution (organic) scales, and their reciprocal intra- and inter-scale constraints. We propose an (epistemological) scale-based definition of constraints that accounts for the concept of synergies as emergent coordinative structures. To illustrate how we can operationalise the notion of multi-scale synergies we use an interdisciplinary model of locomotor pointing. To conclude, we show the value of this approach for interdisciplinary research in sport sciences, as we discuss two examples of task-specific dimensionality reduction techniques in the context of an ongoing project that aims to unveil the determinants of expertise in basketball free throw shooting. These techniques provide relevant empirical evidence to help bootstrap the challenging modelling efforts required in sport sciences.     

A knock to the system: A new sociotechnical systems approach to sport-related concussion

Broader contextual factors that influence concussion management have tended to be overlooked. To address this, the present study used a sociotechnical systems approach to identify perceived responsibilities and applied strategies for three domains of concussion management (i.e., prevention, identification and treatment). Participants were 118 members of the community rugby union system in Australia (69.2% male). Participants from throughout the rugby system (e.g., players, parents, coaches, club management) were asked open-ended questions about their perceived responsibilities and the strategies they use for concussion management. It was found that (a) proper training, technique correction and education were recurrent prevention themes; (b) the majority of key stakeholders felt that they could consistently identify concussion; however, medical aids (medics) were the only system actors who stated a responsibility to use standardised concussion assessment measures and (c) less than one third of the respondents indicated their involvement in treating concussion. This study identifies specific junctures in the system that prevents effective concussion management strategies. A sociotechnical systems approach improves the understanding of concussion prevention, and management beliefs and behaviours.     

基于Bakhshali近似的星载双站SAR成像方法

随着卫星技术的发展与成熟,星载分布式SAR和中高轨SAR越来越受到关注,但是其较长的合成孔径时间和大基线距对双站SAR成像提出了新的要求。基于单站等效思路,提出一种基于Bakhshali近似的双曲等效方法,设计了适用于该方法的CS成像流程。与基于泰勒二阶近似的双曲等效方法相比,该方法满足长合成孔径时间和基线距变化较大的情况下的成像要求。最后通过星载双站SAR的仿真实验验证了该方法的有效性。     

生态脆弱区社会经济与资源环境耦合协调度研究:以云南省昭通市为例

对于生态脆弱地区,探寻其社会经济发展与资源环境的协调发展模式对于实现地区的可持续发展具有重要意义。构建相对资源承载力模型和耦合协调度模型,测算云南省昭通市相对资源人口承载力和经济承载力,并对"经济-资源环境-社会"系统协调发展度进行时空分析。结果表明：1）昭通市相对资源人口承载力超载严重,社会资源承载力低且显著超载;2）相对资源经济承载力处于富余状态,资源的经济价值尚未充分开发;3）昭通市社会经济发展受资源环境制约显著,系统不协调度有拉大趋势。提高第二产业发展水平,优化产业结构是促进昭通市"经济-资源环境-社会"系统协调发展的主要措施。