大理州Rh（D）阴性无偿献血者血清学表型和不规则抗体的调查

目的：了解大理州无偿献血者Rh（D）阴性血型的血清学表现型及不规则抗体存在情况。方法：检测献血者样本136 803例,采用血清学方法确证Rh表现型,使用抗人球蛋白试剂对不规则抗体作筛查。结果：确证Rh（D）阴性献血者209例（0.15%）;其中含不规则抗体1例（0.48%）,血清学表现型中：ccdee 123例（58.85%）,Ccdee 67例（32.06%）,CCdee 7例（3.35%）,ccdEe 6例（2.87%）,CcdEe 5例（2.39%）,CCdEe 1例（0.48%）。该阴性献血者ABO血型分布情况A〉O〉B〉AB。结论：对献血者Rh（D）阴性血型的血清学表现型及不规则抗体作检测,将有利于为临床安全及时有效输血提供保障。     

非规则流重构权下三亚旅游信息并发挖掘算法

对旅游城市的旅游信息深度数据挖掘进行研究有助于提升城市的整体旅游水平。提出一种基于非规则流重构权的三亚旅游信息并发挖掘方法,以非规则流多模态表征游客对于景点选择的不同流向趋势,在非规则流多模态下,通过对于游客期望,目的地形象,游客旅游动机,满意度等几个关键旅游信息的重构权加权,实现最佳匹配度下的游客抉择,同时,建立并发挖掘模型,在非规则流重构权下,对所有景点的信息进行融合挖掘,实现全局最优并发挖掘。采用三亚的5个景点作为研究对象,结果显示,采用该算法进行旅游信息挖掘,每个景点的预测结果误差均在2%以内,对于景点游客预测具有很好的应用价值。     

用非规则节点解偏微分方程的局部微分求积法

In the conventional differential quadrature (DQ) method the functional values along a mesh line are used toapproximate derivatives and its application is limited to regular regions. In this paper, a local differential quadrature (LDQ)method was developed by using irregular distributed nodes, where any spatial derivative at a nodal point is approximatedby a linear weighted sum of the functional values of nodes in the local physical domain. The weighting coefficients in thenew approach are determined by the quadrature rule with the aid of nodal interpolation. Since the proposed method directlyapproximates the derivative, it can be consistently well applied to linear and nonlinear problems and the mesh-free feature isstill kept. Numerical examples are provided to validate the LDQ method.     

Interference of anti-T3 autoantibodies in the measurement of total and free T3 in serum

A case of anti-trilodothyronine autoantibodies is presented in this report. The thyroid hormone profile of a hypertensive patient, with multinodular goiter and history of exogenous thyroid hormone therapy, was found to be highly ambiguous. The total as well as free T3 levels were consistently high (out of range) whereas the T4 (total and free) values were always within normal limits. The thyrotropin was found to be partially suppressed. Very low T3-Uptake indicated some kind of interference in the immunoassays. We incubated the sera with the radio-iodine labelled T3 and observed that the patient's serum bound about ten times more radioactivity than a control run in parallel. On further resolving the serum proteins on cellulose acetate electrophoresis, the radioactivity was detected in the γ-globulin band. Therefore it was established that the patient's serum carried the antibodies reactive with T3 which were interfering in the immunoassays. Elevated anti-thyroid microsomal antibodies were also present in the patient's serum. The anti-T3 antibodies were highly specific for T3 and did not show any cross reactivity with the T4 or its analogues used in the estimation of free T4.     

科学研究中的不规范行为与信息污染

信息污染是信息时代的必然产物,导致信息污染的原因很多,其中科学研究中的不规范行为是导致信息污染的主要原因之一,本文侧重分析了科学研究中不规范行为与信息污染的关系,指出这类信息污染对科学信息的传播具有极大的负面影响     

论大学生非正规就业的问题与策略

传统意义上的就业概念,高校就业率统计均是指以发放派遣证为标准,而发放派遣证的条件是正规就业,但实际上,从就业去向上讲,非正规就业已成为大学生就业的一个重要趋势。所以,应扩大“就业”概念的外延,将非正规就业纳入到就业渠道中来。高等学校务必以大学生为本,密切关注学生未来从事的职业及其人生走向,全面提升毕业生的就业率和就业满意度。     

女大学生经期参加体育运动与月经不调关系的调查分析

对集美大学500名女学生进行了月经情况的随机抽样调查,发现体育专业月经不调人数发生率高于非体育专业女生,经期运动组的女生月经不调人数高于经期不运动组的女生,月经不调人数具有显著性差异。由此可见女大学生经期参加体育运动的运动负荷必须加以调整。     

考虑不规则风浪影响的最小油耗航速模型

为提高单船营运能效,提出一种考虑不规则风浪影响的最小油耗航速定量计算模型．首先进行航段划分,获取海况数据;然后通过增加航行功率修正船舶失速的方法,构建考虑风浪影响的单位时间油耗模型;最后以每航段航速为决策变量,建立最小油耗航速非线性优化模型.考虑到实船应用中最小油耗航速优化算法需具有快速寻找全局最优解的特点,设计初始值算法．以实船某航次运营为例进行了油耗及最小油耗航速计算,结果显示：每海里油耗模型理论值与实测值相对误差在可接受范围内;与不考虑不规则风浪影响的计算模型(平均航速)相比较,采用这种方法计算出的油耗减少了1%,节能效果初见成效．     

周边不规则大型深基坑地下水控制设计

地下水控制是大型深基坑工程中的关键技术。结合某周边不规则的深基坑工程,从基坑周边既有工程环境、施工场地条件、基坑地质和含水层特征等多方面综合考虑,对基坑场地内上层滞水和孔隙承压水分别提出控制设计思路,给出排水管路、深井降水网布置设计方法,以及降水井结构设计图,最后评价地下水控制对深基坑周围环境的影响。对于类似建筑,具有一定的参考价值。     

Assessment of antinuclear antibodies (ANA): National recommendations on behalf of the Croatian society of medical biochemistry and laboratory medicine

Antinuclear antibodies (ANA) represent a family of autoantibodies targeting ubiquitous cellular constituents and are a hallmark of systemic inflammatory autoimmune rheumatic diseases named connective tissue diseases (CTD). The gold standard method for ANA determination is indirect immunofluorescence (IIF) on the human laryngeal epidermoid carcinoma cell line type 2 substrate (HEp-2), but with increasing demand for ANA testing, novel methods eased for automation emerged, which allows testing by staff less experienced in this specific field of laboratory diagnostic. In 2016 The working group (WG) for laboratory diagnostics of autoimmune diseases as part of the Committee for the Scientific Professional Development of the Croatian Society of Medical Biochemistry and Laboratory Medicine (CSMBLM) published the data of a survey regarding general practice in laboratory diagnostics of autoimmune diseases in Croatia. Results indicated high diversity in the performance of autoantibody testing as well as reporting of the results and indicated the need of creating recommendations for the assessment of ANA that would help harmonize diagnostics of systemic autoimmune rheumatic diseases in Croatia. This document encompasses twenty-seven recommendations for ANA testing created concerning indications for ANA testing, preanalytical, analytical, and postanalytical issues, including rational algorithm and quality control assurance. These recommendations are based on the relevant international recommendations and guidelines for the assessment of ANA testing and relevant literature search and should help to harmonize the approach in ANA testing and clarify differences in interpretation of the results obtained using different methods of determination.