路面病害及改造工程施工工艺控制——以国道324线小盈岭-马巷段为例

结合国道324线小盈岭-马巷段工程实际,通过分析旧路病害原因,摸索与试验旧路病害处置、橡胶沥青应力吸收层及橡胶沥青混合料路面的施工工艺、施工方法、质量控制等,为旧水泥砼路面加铺沥青砼面层（即白加黑）提供了一套新的思路与工艺.     

Mini-review:Is alcohol consumption associated with gastroesophageal reflux disease?

Gastroesophageal reflux disease (GERD) is one of the most common disorders with an increasing incidence and prevalence. Alcohol consumption may be a risk factor for GERD; however, the relationship remains to be fully elucidated. The results of different studies are diverse and contradictory. Systematic investigations concerning this matter are inappropriate and further well-designed prospective studies are needed to clarify the effect of alcohol on GERD.     

五四女儿的病理报告——庐隐小说一解

庐隐是五四时期著名的女性小说家,她擅长于依据自身的人生体验,描写当时知识女性面临的困境.她的小说中出现了一系列的女病人形象,正是通过展示女病人的病因与社会机制的矛盾性,庐隐显示了她的朦胧的女性主义立场.     

城市老年人生命质量影响因素的研究——以规律健身为视角

目的：探究城市老年人生命质量影响因素，积极应对人口老龄化的严峻挑战。方法：采用自编问卷，借鉴“SF-36生命质量调查问卷（中文第二版）”，对城市老年人进行调查和访谈。结果：影响城市老年人生命质量因素主要有社会人口学、经济收入、患慢性病、社会参与、健身状况等。其中老年人“婚姻及居住方式”“养老保险”“就医决策”“规律健身状况”和“医疗费用月支出”的回归效应非常显著（P＜0.01），而“工作与否”和“每次医疗费用支出”的回归效应显著（P＜0.05）。结论：对老年人健康促进和生命质量干预主要目的是对影响因素进行调节，降低影响生命质量风险因子的负作用，老年人是否患慢性病及参与规律健身行为的阶段等是影响老年人生命质量提升的重要因子，超过12个月以上规律健身行为对城市老年人身心健康和生命质量提升的积极作用最为显著。     

大学图书馆开展阅读疗法初探

文章针对当代大学生普遍存在心理疾病的现实,结合阅读疗法的特殊性,分析大学图书馆开展阅读疗法的重要性,并提出高校图书馆开展阅读疗法的一些可行性建议。     

Is adult celiac disease really uncommon in Chinese?

Celiac disease (CD) is a type of intestinal malabsorption syndrome, in which the patients are intolerant to the gliadin in dietary gluten, resulting in chronic diarrhea and secondary malnutrition. The disease is common in Europe and the United States, but only sporadic reports are found in East Asia including China. Is CD really rare in China? We examined 62 patients by capsule endoscopy for chronic diarrhea from June 2003 to March 2008. Four patients with chronic diarrhea and weight loss were diagnosed to have CD. Under the capsule endoscopy, we observed that the villi of the proximal small bowel became short, and that the mucous membrane became atrophied in these four patients. Duodenal biopsies were performed during gastroscopy and the pathological changes of mucosa were confirmed to be Marsh 3 stage of CD. A gluten free diet significantly improved the conditions of the four patients. We suspect that in China, especially in the northern area where wheat is the main food, CD might not be uncommon, and its under-diagnosis could be caused by its clinical manifestations that could be easily covered by the symptoms from other clinical situations, particularly when it came to subclinical patients without obvious symptom or to patients with extraintestinal symptoms as the initial manifestations.     

Adiponectin levels are associated with the number and activity of circulating endothelial progenitor cells in patients with coronary artery disease

Objective: To study the relationship between plasma adiponectin concentration and the functional activities of circulating endothelial progenitor cells (EPCs) in patients with coronary artery disease (CAD). Methods: Circulating EPCs were enumerated as AC133+/KDR+ cells via flow cytometry and identified by co-staining with Dii-acLDL and fluorescein isothiocy-anate (FITC)-conjugated lectin under a fluorescent microscope. The migratory capacity of EPCs was measured by modified Boyden chamber assay. Adhesion capacity was performed to count adherent cells after replating EPCs on six-well culture dishes coated with fibronectin. Results: The number of circulating EPCs (AC133+/KDR+ cells) decreased significantly in CAD patients, compared with control subjects [(74.2±12.3) vs (83.5±12.9) cells/ml blood, P<0.0\]. In addition, the number of EPCs also decreased in CAD patients after ex vivo cultivation [(54.4±8.6) vs (71.9±11.6) EPCs/field, P<0.01]. Both circulating EPCs and differentiated EPCs were positively correlated with plasma adiponectin concentration. The functional activities of EPCs from CAD patients, such as migratory and adherent capacities, were also impaired, compared with control subjects, and positively correlated with plasma adiponectin concentration. Conclusion: The study demonstrates that the impairment of the number and functional activities of EPCs in CAD patients is correlated with their lower plasma adiponectin concentrations.     

新发展理念视阈下的我国畜禽疫病防控

畜禽疫病的发生与流行是制约我国养殖产业可持续发展的关键因素之一。同时,畜禽疫病还会对动物性食品的源头安全、人民健康以及生态环境造成严重危害。一些烈性畜禽传染病的暴发甚至还会给社会稳定和国家安全带来重大冲击。因此,新时期科学有效地防控畜禽疫病是我国养殖业实现转型升级与可持续发展的国家重大需求。文章从我国畜禽疫病防控的重要意义与历史成就切入,分析了我国畜禽疫病的流行现状及防控困难,并就此提出了未来科技创新的重点方向。     

基因技术的发展和女性自主选择的可能

基因技术的发展使人们通过干预生殖过程来控制遗传疾病变得可能.这种做法可能给处于中国特定社会文化环境中的女性带来压力和不利.能否减轻女性的压力,改善不利的环境,关键不在于女性是否具备足够的自主能力,而在于技术运作的社会外部环境是否提供足够的资源,让她们有可能作出自主的选择.     

Oxidative stress in Parkinson’s disease

Oxidative stress contributes to the cascade, leading to dopamine cell degeneration in Parkinson’s disease. However, oxidative stress is intimately linked to other components of the degenerative process, such as mitochondrial dysfunction, excitotoxicity, nitric oxide toxicity and inflammation. It is therefore difficult to determine whether oxidative stress leads to or is a consequence of, these events. Oxidative stress was assessed by estimating lipid peroxidation product in the form of thiobarbituric acid reactive substances, nitric oxide in the form of nitrite & nitrate. Enzymatic antioxidants in the form of superoxide dismutase, glutathione peroxidase, catalase, ceruloplasmin and non enzymatic antioxidant vitamins e.g. vitamin E and C in either serum or plasma or erythrocyte in 40 patients of Parkinson’s disease in the age group 40–80 years. Trace elements e.g. copper, zinc and selenium were also estimated. Plasma thiobarbituric acid reactive substances and nitric oxide levels were Significantly high but superoxide dismutase, glutathione peroxidase, catalase, ceruloplasmin, vitamin-E, vitamin-C, copper, zinc and selenium levels were significantly low in Parkinson’s disease when compared with control subjects. Present study showed that elevated oxidative stress may be playing a role in dopaminergic neuronal loss in substentia nigra pars compacta and involved in pathogenesis of the Parkinson’s disease.