阑尾源性弥漫性腹膜炎125例围手术期处理

目的探讨阑尾源性弥漫性腹膜炎围手术期处理方法。方法对1989年11月至2002年12月作者所在医院手术治疗的125例阑尾炎所致弥漫性腹膜炎临床资料进行回顾性研究。结果治愈120例，死亡5例。切口感染31例，肺炎5例，肠粘连梗阻8例。肠间或盆腔脓肿8例。结论对阑尾源性弥漫性腹膜炎患者术前、术后注重水、电解质、酸碱平衡的维持和失衡的纠正、有效抗生素应用、中西医结合治疗，术中彻底清理腹腔，妥善放置腹腔引流管及切口皮下引流管．强心、利尿等综合处理措施，保持内环境稳定。减少并发症发生．可以明显改善预后和病程转归。     

青年食管癌与中老年食管癌外科诊治的比较研究

分析青年与中老年食管癌患者的临床特征及外科治疗效果。回顾性分析49例青年和98例中老年食管癌患者的临床资料。结果:青年食管癌占同期食管癌的6.55%,两组患者在性别比例、肿瘤病变部位、病理类型、分化程度等差异无统计学意义(P>0.05);在术后病理分期、根治性切除率、术后并发症发生率上差异均有统计学意义(P<0.05);青年组与中老年组的手术死亡率分别为0.0%和2.0%,两组生存率差异无统计学意义(P>0.05)。结果表明,青年人食管癌肿瘤病期偏晚,手术切除率更低,术后并发症发生率及手术死亡率优于中老年组,两者在生存预后差别无统计学意义。     

CFS的诊治及其运动处方的应用

查阅了近十几年的HIGHWIRE和MEDLINE上有关慢性疲劳综合症预后的文献,进行了系统的综述,介绍了慢性疲劳综合症(CFS)的诊断标准及病理机制,同时对各疗法效果进行了比较.结果表明,科学的制定运动处方,采用"阶梯运动疗法"能有效改善患者疲劳程度,减轻并发症状,提高运动能力.同时没有任何副作用.建议采用"阶梯运动疗法"治疗CFS,并对运动疗法处方的构成进行了归纳.     

Colorectal cancer, one entity or three

Understanding of the mechanism ofcolorectal carcinogenesis has been gaining momentum for some years on account of its high incidence and impact on the lives of individuals affected. Different genetic abnormalities have been found in colorectal cancers from different sites. For example, proximal colon cancer is usually related to the nucleotide instability pathway, as mi-crosatellite instability (MSI). However, distal colon cancer is usually associated with specific chromosomal instability (CIN). The development of cancer at the rectum, though similar to that at the colon, displays its own unique features. These differences might be partially attributed to different embryological development and physiological circumstances. Environmental factors such as diet and alcohol intake also differ in their role in the development of tumors in the three segments, proximal colon, distal colon, and rectum. "Proximal shift" of colon cancer has been known for some time, and survival rates of colorectal cancer are higher when rectal cancers are excluded, both of which emphasize the three different segments of colorectal cancer and their different proper-ties. Meanwhile, colonic and rectal cancers are distinctive therapeutic entities. The concept of three entities of colorectal cancer may be important in designing clinical trails or therapeutic strategies. However, the dispute about the inconsistency of data con-ceming the site-specific mechanism of colorectal carcinoma does exist, and more evidence about molecular events of carcino-genesis and targeted therapy needs to be collected to definitely confirm the conception.     

原发性蛛网膜下腔出血预后因素探讨

目的：探讨原发性珠网膜下腔出血的预后因素。方法：通过对126例原发性珠网膜下腔出血住院病人分死亡组,生存组进行比较分析。结果：死亡组中重症出血,近期再次出血,脑动脉痉挛,合并内科并发症明显高于生存组。结论：影响原发性珠网膜下腔出血预后因素主要是重症出血,近期再次出血,脑动脉痉挛,合并内科并发症。针对上述情况,临床上认真观察,积极防治,可减低死亡率。