人工紫外线照射对家兔几项生理指标,心电图及眼睛的影响

采用30瓦水银石英紫外灯照射健康家兔18小时,测定了紫外线对家兔几项生理指标、心电图及眼睛的影响。结果,兔体温、红细胞渗透脆性不受影响;心电图变化不明显,呼吸数、红细胞数、血红蛋白含量、白细胞数在照射后均有增加(P>0.05),但是,白细胞数在照射6小时后显著增加(0.01相似文献   

Cs对家兔窦房结和主动脉前庭的电生理效应

目的 :探讨CsCl对心脏慢反应自律细胞的电生理效应。方法 :应用细胞内微电极记录技术 ,观察了 16例家兔窦房结和主动脉前庭 (左心室流出道 )自律细胞动作电位的特征。以分析CsCl对窦房结和流出道自律细胞作用的异同。结果 :给予 2mmol/LCsCl灌流后 ,两自律细胞自发慢反应电位的VDD及RPF均明显减慢 (P <0 .0 5 ) ,10min左右达到最大效应 ,而MDP、APA、Vmax、APD、APD50 、APD90 与正常对照比均无明显差别 (P >0 .0 5 )。结论 :CsCl对窦房结起搏细胞和主动脉前庭自律细胞的起搏离子流有明显抑制作用。     

法式囊三肽囊素(bursin)在兔圆小囊、肠相关淋巴组织（蚓突）中免疫组化定位特征研究

The distribution of bursin in sacculus rotundus and gut-associated lymphoid tissues was investigated in rabbit. by immuno-histochemical staining method with anti-bursin monoclonal antibody(McAb)2F9o4.The results indicated that the appearance of the bursin-containing cells coincided with the morphodifferentiation and growth process in rabbit.Bursin immunized cells not only distributed in dome epithelium and mucosal epithelium,but also in follicular germinal center,dome, T-cell area,goblet cell,inter-epithelial lymphocyte and cap-zone of sacculus rotundus.This founding suggested that bursin- containing cells in sacculus rotundus might play an important role in intestinal mucosal immunity.     

介绍一种新的兔心脏骤停模型

以兔为研究对象,探讨电刺激法致心脏骤停模型建立的方法。结果电刺激致兔心脏骤停时血压骤降至2.36±0.92kPa,心电图600～700次/min室颤波;复苏后血压仍保持在较低水平,心电图S-T段持续压低;再灌注期血自由基含量较实验前显著升高(P<0.01)。表明电刺激法致兔心脏骤停模型符合心脏骤停的病理生理过程。     

论汉代民间的兔信仰

汉画中有很多悬挂兔肉的画面,也有很多捕猎兔的画面,说明汉代兔信仰是因兔有食用的价值。汉画中的捣药兔成为一个固定的形式,陪伴在仙人西王母身边。这说明兔有药用价值;可以说,捣药兔是汉代人对于远古发现中医药部族的怀念和记忆。汉画月中兔形象既表现了汉代人的天文月相知识又表现了汉代人的养生修炼观念和长生成仙的愿望。北京地区的兔儿爷崇拜,正是汉代兔信仰的现代依存和活化形态。     

厄普代克作品中女性形象解读

厄普代克的作品中,无论是《兔子四部曲》、《S.》、《夫妇们》还是其他,女性始终是小说的重要内容,我们可以看到女性在美国历史上地位的变化,女性意识的觉醒始终贯穿了整个小说系列的内容。可以说,厄普代克的作品就是女性地位的变革史,它的系列小说不仅仅是文学史的表征,同时更是时代史的重要凝结。女性地位和女性意识一直是值得探讨的话题,本文将重点以厄普代克的几部小说为例来展开深入探讨,以此来解读其小说中的女性形象。     

Relation between arterial stiffness and aerobic capacity: Importance of proximal aortic stiffness

Brachial-ankle pulse wave velocity (baPWV) has become a popular modality of arterial stiffness measurement. However, its projected arterial segment does not include the proximal aorta which plays important roles for attenuating cardiac pulsation and reducing afterload. We hypothesised that aerobic capacity would be more strongly associated with PWV including the proximal aorta than that omitting the proximal aorta. To test our hypothesis, we compared the association between aerobic capacity and arterial stiffness parameters omitting vs. including the proximal aorta (i.e. baPWV vs. heart-ankle PWV [haPWV]) in 82 apparently healthy men (18–64 years). Estimated VO_2max significantly correlated with baPWV (r?=??0.394, P?<?.001), and more strongly with haPWV (r?=??0.546, P?<?.001). The forward stepwise multi-regression analysis revealed that haPWV (β?=??0.335), as well as age, heart rate, and body mass index (β?=??0.280 to ?0.297), was a significant independent determinant explaining variance of estimated VO_2max. These results suggest that aerobic capacity is influenced more strongly by the proximal aortic stiffness than distal aortic stiffness.     

刺五加对家兔白细胞的影响

利用环磷酰胺诱导家兔白细胞数目减少，模拟病态系统，建立实验机制．观察刺五加糖类提取液使家兔白细胞数目减少后的再恢复效果．     

中药制剂通心络抗家兔动脉粥样硬化实验研究

目的　用高胆固醇饲料复制动脉粥样硬化模型,观察通心络生药对家兔动脉粥样硬化的预防作用,并探讨其对血脂和血管细胞粘附分子-1(VCAM-1)mRNA表达的影响.方法　选30只雄性健康家兔,随机分为三组:①对照组10只,喂以普通饲料;②高胆固醇组10只,喂以含1.5%胆固醇的饲料;③通心络组10只,喂以含1.5%胆固醇的饲料和通心络生药0.72g/(kg·d).12周后测定:①血脂;②主动脉内膜/中膜厚度比值及斑块面积;③RT-PCR法检测主动脉中VCAM-1mRNA表达的水平.结果　通心络组和高胆固醇组的血清总胆固醇水平均显著高于对照组(P<0.01),通心络组低于高胆固醇组(P<0.05);通心络组主动脉内膜/中膜厚度比值、斑块面积和主动脉VCAM-1mRNA表达量均低于高胆固醇组[(0.57±0.06)vs(1.06±0.09),P<0.01;(38.93±3.42)%vs(71.75±3.82)%,P<0.01;(0.59±0.15)vs(0.91±0.18),P<0.01].结论　通心络具有抗动脉粥样硬化作用,可降低血脂和主动脉组织VCAM-1mRNA的表达.     

Complex pathologies of angiotensin II-induced abdominal aortic aneurysms

Angiotensin II (AngII) is the primary bioactive peptide of the renin angiotensin system that plays a critical role in many cardiovascular diseases. Subcutaneous infusion of AngII into mice induces the development of abdominal aortic aneurysms (AAAs). Like human AAAs, AngII-induced AAA tissues exhibit progressive changes and considerable heterogeneity. This complex pathology provides an impediment to the quantification of aneurysmal tissue composition by biochemical and immunostaining techniques. Therefore, while the mouse model of AngII-induced AAAs provides a salutary approach to studying the mechanisms of the evolution of AAAs in humans, meaningful interpretation of mechanisms requires consideration of the heterogeneous nature of the diseased tissue.