某高层商住楼结构选型中的一些新尝试

通过某高层商住楼结构选型的探讨，尝试采用了框支-短肢剪力墙这种结构形式；针对这种结构形式的优缺点，对重要及薄弱部位采取了有效的加强措施，保证了整个结构安全可靠，设计合理。     

论翁方纲关于米芾、董其昌书法的题跋

翁方纲是清代著名的学者和书法家，其书法质朴，浑厚，但由于缺乏创新而被后人批评,本文从翁方纲关于米芾、董其昌等书家书法的题跋入手，着重阐述了翁氏实用、复古、理性的实践观点，较全面地探究了翁氏书法得失的原由．     

浅释数字化测图外业中的简码操作

概述了简码记录在全站仪野外数字化作业过程中的操作方法，并比较了简码记录与全数字信息码记录的优劣，因而简码记录是值得推广。     

校报要让短稿唱主角

当前高校校报普遍存在着长稿偏多的现象，根据高校校报自身的任务和特点，应该在刊载字数、版面安排，写作方法等方面采取措施多采用短稿，以加大信息承载量。     

"文学不等于一般的宣传"——关于建国初期丁玲对教条主义的批判

建国初期,在文学成为政治工具的时代,教条主义几乎成了文学创作中的顽症.为了纠正文学创作中的不良倾向,丁玲不但富有胆识地提出了文学创作中所存在的"教条主义"的问题,而且侧重从主题题材、形象塑造和文学功用等方面对文学创作中教条主义的表现和公式化、概念化的成因做出了相当深入的挖掘和剖析,切中时弊,表现了"战胜教条主义"的努力.丁玲对教条主义的批判,既与50年代外在文学情势的变化相关,更关乎其对"五四"文学传统的理解和固守.     

“被”字句的派生问题研究

回顾以往对汉语的“被”字句派生问题的研究,发现相关文献中对“被”字句的假设存在不少问题,文章提出将“被”分析为《最简方案》框架下的次动词的假设,“被”字句通过“被”字的移位而生成,长短被字句以同一模式生成,两者具有类似的句法结构,其派生可通过次动词的基本特征来解释。     

宋初小令词坛浅议

宋初小令主要继承唐五代词风的余绪,其一方面强化了唐五代文人开创、定型的创作范式,进一步确立了“本色”词的主流地位,另一方面,也为宋词鼎盛时期的到来,起到了“导夫先路”的作用。     

《短信语言修辞艺术研究》序

傅远碧副教授的专著<短信语言修辞艺术研究>专从修辞艺术的角度研究短信语言,在短信论著中属于拓荒之作.综观此书,具有以下特点:从修辞角度所作的分类细致深入;精心搜集的语料丰富多姿;通过论析,突显短信语言多角度呈现的修辞效果.本书的问世,无疑为短信语言研究提供较多的经验.     

高等教育自学考试教材《教育评估和督导》评析——兼论自学考试中的教与学

高等教育自学考试中的教与学是两个基点,而教材是基本依据。目前指定的《教育评估和督导〉存在一些问题,影响了教育的效果与质量。如何解决这些问题呢？（1）根据短线自考生的特点选择教材;（2）对现有教材进行适当修订;（3）采用合适的教学方法与策略。     

CRISPR/Cas: a Nobel Prize award-winning precise genome editing technology for gene therapy and crop improvement

Since it was first recognized in bacteria and archaea as a mechanism for innate viral immunity in the early 2010 s,clustered regularly interspaced short palindromic repeats(CRISPR)/CRISPR-associated protein(Cas) has rapidly been developed into a robust, multifunctional genome editing tool with many uses. Following the discovery of the initial CRISPR/Cas-based system, the technology has been advanced to facilitate a multitude of different functions. These include development as a base editor, prime editor, epigenetic editor, and CRISPR interference(CRISPRi) and CRISPR activator(CRISPRa) gene regulators. It can also be used for chromatin and RNA targeting and imaging. Its applications have proved revolutionary across numerous biological fields, especially in biomedical and agricultural improvement. As a diagnostic tool, CRISPR has been developed to aid the detection and screening of both human and plant diseases, and has even been applied during the current coronavirus disease 2019(COVID-19) pandemic. CRISPR/Cas is also being trialed as a new form of gene therapy for treating various human diseases, including cancers, and has aided drug development. In terms of agricultural breeding, precise targeting of biological pathways via CRISPR/Cas has been key to regulating molecular biosynthesis and allowing modification of proteins, starch, oil, and other functional components for crop improvement. Adding to this, CRISPR/Cas has been shown capable of significantly enhancing both plant tolerance to environmental stresses and overall crop yield via the targeting of various agronomically important gene regulators. Looking to the future, increasing the efficiency and precision of CRISPR/Cas delivery systems and limiting off-target activity are two major challenges for wider application of the technology. This review provides an in-depth overview of current CRISPR development, including the advantages and disadvantages of the technology,recent applications, and future considerations.