用于移动计算环境中的新移动性管理和路由方案

由因特网工程任务组 (IETF)提出的不对称路由移动性管理方案存在产生的移动性管理信令流量大的问题 .考虑到一些现有因特网应用的特征 ,提出了一个可在移动计算中显著降低移动性管理信令的新方案 ,该方案采用转向代理和局部代理机制 .对新方案进行计算机模拟 ,结果表明 ,新方案明显降低了网络的远程信令流量 .     

Pathways to performance: an examination of entry pathway and first-year university results

Although diversity at universities has increased dramatically over the past 150 years, many groups are still under-represented relative to their proportion in the general population. Initiatives to improve diversity have included the increased use of entry pathways other than direct admission from secondary school. As admissions via these alternative entry routes have increased, concerns have grown that alternative-entry students are not well prepared for university study. Here, we describe the outcomes for students entering university via one alternative entry pathway and compare them with those of students entering from secondary school. We used quantile regression with restricted cubic splines to examine the relationship between secondary school performance (quantified by the Australian Tertiary Admission Rank; ATAR), pathway of entry to university, and performance during first year university. Entry pathway significantly affects the conditional distribution of first-year marks. Outstanding performance is largely confined to students entering university from secondary school (Year 12 entry), rather than from an institution for technical and further education (TAFE). Concomitantly, for any given ATAR, the risk of failure is higher amongst Year 12 entry students than among TAFE entry students. The results have substantial implications for changes in admission criteria and for the public funding of universities.     

卡思卡特城堡

It is worthy of noting that, whilst Crookston Castle witnessed the earlier and happier portion of Mary's variegated life,     

Ineffective pathways and the price of conjecture

The inclusion of children with special educational needs into mainstream schools needs effort and cooperation by all those involved. Both educators and medical professions need to be skilled in identifying and supporting neurodiversity. This study explores the cross-professional understanding and support of four of the most prevalent neurodiversities: autism spectrum condition, attention deficit hyperactivity disorder, developmental coordination disorder and dyslexia, to evaluate the efficiency of the diagnostic pathway and the subsequent support. Questionnaires were distributed throughout a number of training events for medical and educational practitioners asking what a condition was, and how it could be supported. Using a thematic analysis, data from 189 responses were examined and cross-referenced with diagnostic criteria, in addition to identifying the overarching themes of support. Results show a serious gap in awareness and knowledge of neurodiversity in both medical and educational sectors, followed by a cacophony of intervention, breaking the pathway for diagnosis before it begins and ultimately failing children and their families.     

软交换监测系统中的CDR合成技术研究

信令监测系统是做好软交换网络的维护支撑及话务分析工作的有力工具。呼叫记录CDR的合成,是进行话务分析的基础,是整个监测系统的核心技术。该文针对软交换网络中所涉及的有关网络协议,分别研究了其CDR合成技术,并探讨了CDR的关联和去重问题。     

基于模糊集定性比较分析法的我国各省份产业集群创新效率与路径研究

集群是创新系统与企业之间的中观层面。集群机制促进了技术、人才和知识资源的聚集、企业之间的技术溢出和研发合作,进而起到了提高创新效率的作用,然而,不同区域聚集的集群显示出创新效率的差异,以及基于差异的集群创新能力提升的不同路径。从集群的视角出发,以我国各省创新型集群数据为基础,首先使用DEA-Malmquist法计算各省份集群的创新效率,并根据创新效率的情况将集群分为全面型、技术进步型、技术薄弱型、规模经济型4类集群,再使用模糊集定性比较分析法识别出不同情形下影响创新效率的7条路径,根据路径的特点将其总结为全面性、环境型、聚集型,得到不同类型的集群的创新提升路径,得到的研究结果对于丰富集群创新战略和管理理论与实践具有一定意义。     

供应链政策与企业技术创新 ——来自政府认定供应链创新试点企业的经验证据

利用2018年9月商务部等8部门联合启动的“全国供应链创新与应用试点”为准自然实验场景,采用双重差分倾向得分匹配法（PSM-DID）探究供应链政策对企业技术创新的影响。研究发现：供应链创新试点项目实施后的第二年,试点企业的技术创新水平显著提升;进一步研究发现对于非国有企业、成熟期企业、冗余资源较多以及供应链集中度高的企业,这种提升作用更为显著。此外,采用事件研究法和Heckman两阶段模型,从资本市场反应的视角证实了供应链创新试点影响企业技术创新过程中的信号传递机制,且这种信号的有效性受企业生命周期和供应链集中度影响。     

葛根素抗炎作用研究进展

葛根素是从葛根（Radix Pueraria）的根部提取的一种异黄酮.它具有改善血管循环、抗氧化应激、治疗骨质疏松以及降血糖等作用.研究表明葛根素对免疫细胞、炎症因子、信号通路以及炎症疾病都有重要的影响.文章着重对葛根素在抑制炎症方面的作用作一简要概述.     

高强度间歇训练对不同类型肌纤维代谢与分布的调节*

目的：探讨急性（1次）和长期（8周）高强度间歇训练（HIT）对SD大鼠不同类型骨骼肌纤维代谢与分布的影响。方法：30只雄性SD大鼠随机分为安静对照（r-C）组、急性HIT（a-HIT）组和长期HIT（c-HIT）组,每组n＝10只。a-HIT组进行1次急性HIT,c-HIT组进行8周HIT,r-C组保持安静状态。实验后分离胫骨前肌（快肌,II型肌纤维为主）和比目鱼肌（慢肌,I型肌纤维为主）,比色法测定琥珀酸脱氢酶（SDH）和乳酸脱氢酶（LDH）活性,ATP酶染色法鉴定肌纤维类型（I、II）,Western Blot法测定腺苷酸活化蛋白激酶（AMPK）α亚基（AMPKα）、磷酸化AMPKα（p-AMPKα）、p38促分裂原活化蛋白激酶（p38 MAPK）、p-p38 MAPK、钙调神经磷酸酶（CaN）、过氧化物酶体增殖物激活受体γ 辅激活因子1α（PGC-1α）、激活T细胞核因子（NFAT）c1亚基（NFATc1）蛋白相对表达量以及肌球蛋白重链（MHC）亚型（I、IIa、IId/x和IIb）百分构成比。结果：与r-C组比较,a-HIT组比目鱼肌和胫骨前肌糖原含量均下降（P<0.05）,p-AMPKα/AMPKα、p-p38 MAPK/p38 MAPK、CaN、PGC-1α和NFATc1蛋白表达量升高（P<0.05）;c-HIT组力竭时间延长（P<0.05）,胫骨前肌LDH活性升高,比目鱼肌和胫骨前肌糖原含量、SDH活性以及PGC-1α和NFATc1蛋白表达量升高（P<0.05）,比目鱼肌IIa型和IIb型肌纤维比例减少（P<0.05）,I型肌纤维比例增加（P<0.05）,胫骨前肌IIb和IId/x型肌纤维减少（P<0.05）,IIa和I型肌纤维增加（P<0.05）。结论：一次急性HIT可同时募集快肌和慢肌纤维并激活多种信号转导通路;而长期HIT则提高快肌中I型和IIa型肌纤维以及慢肌中I型肌纤维比例,上调快肌和慢肌糖原含量和有氧代谢酶活性以及快肌无氧代谢酶活性,最终改善运动能力。