Determination of Biological Variance and Validation of a Fluorometric Assay for Measurement of α-l-Iduronidase Activity in Dried Blood Spots Samples: The First Experience in Iran

Methods for assaying lysosomal diseases in dried blood samples are very useful today due to its several advantages related to the stability of samples, its transportation, handled and analysis, and its potential use for newborn screening compared to traditional methods in leucocytes samples. For this reason, it is important to validate these assays before being used in routine laboratory. Because of different in biological markers based on ethnicity, we aimed this study to validation a DBS-based fluorometric assay for measurement of α-l-Iduronidase activity for diagnosis of MPS I patients in Iran. DBS samples were collected from 15 MPS I patients and 60 healthy age matched subjects. Diagnostic value, biological variance and α-l-Iduronidase activity were determined. DBS α-l-Iduronidase activity was significantly higher in male subjects than in female group. Using a cut-off level of 1.08 µmol/spot 20 h, sensitivity and specificity were 100 and 98 %. The linearity of test was proved and we showed that within-run and between run precision were 5.6 and 14.66 %. Measurement of α-l-Iduronidase activity in DBS samples is an accurate test for diagnosis of MPS I and because of its rapid shipping and simplicity to keeping, DBS-based enzyme activity could be considered as a useful diagnostic tool in this disease.     

文本类型理论观照下的红色旅游景介英译

文本类型理论有助于客观地分析文本的功能,从而采取适当的翻译策略。从文本类型理论入手,结合"信息突出"和"经济简明"两大策略原则,对湖南红色旅游景介汉英翻译做实例分析,验证了文本类型的分析及两大策略原则地结合在红色旅游景介翻译领域的可操作性。     

《新编日语》中拟声拟态词的考察

日语的拟声拟态词是能够表达自然界和人的声音及样态的词汇。它具有丰富的表现力,是日语的主要特征词汇之一。对于中国的日语学习者而言,拟声拟态词的学习也是难点之一。追其原因,是因为在中国的日语教育中并不重视拟声拟态词的教学的缘故。本论文以日语精读教材《新编日语》为对象,主要围绕着教材中拟声拟态词的实际情况及编撰过程中存在的缺陷,以期对我国日语教材的编写尽绵薄之力。     

Producing the docile body: analysing Local Area Under-performance Inspection (LAUI)

Sir Michael Wilshaw, the head of the Office for Standards in Education (OfSTED), declared a ‘new wave’ of Local Area Under-performance Inspections (LAUI) of schools ‘denying children the standard of education they deserve’. This paper examines how the threat of LAUI played out over three mathematics lessons taught by a teacher in her first year in the profession. A Foucauldian approach is mobilised with regard to disciplinary power and ‘docile bodies’. The paper argues that, in the case in point, LAUI was a tool mediating performative conditions and, ultimately, the docile body. The paper will be of concern to policy sociologists, teachers, school leaders, and those interested in school inspection.     

论律师年检制度之完善

律师年检制度是一项合法的制度,正确认识其优点,从完善律协的自治权,年检权力交于律协,取消律师会员会费、区别收取律所会费,建立律师执业登记制度四个方面完善我国律师年检制度,更好地发挥律师年检制度应有的作用。     

科技期刊构建学术不端文献检测体系分析

为提高编辑部学术不端文献检测的严谨性,对编辑部学术不端文献的检测过程和界定标准进行探讨,提出构建科学规范的学术不端文献检测体系的具体措施,使学术不端文献的检测工作得到较好的执行,对目前检测存在的主要问题进行了分析,认为建立科学规范的检测体系,是学术不端文献检测的关键。     

改革开放以来外资检验检测认证机构在华发展历程研究

为系统深入研究改革开放以来外资检验检测认证机构(TIC)在华发展状况,以14家典型外资TIC机构为研究对象,将外资TIC机构在华发展历程分为探索、培育、快速发展、高质量发展4个阶段。研究发现,不同阶段外商投资政策与行业监管政策的调整直接影响到外资TIC机构在华发展战略、经营策略、业务方向、成长速度等;外资TIC机构在华发展的主要经验包括全国布局分支机构、多元业务统筹经营、开展并购抢占市场、紧贴中国市场需求、积极进军新兴领域、参与社会公益事业。基于研究发现,提出继续深化改革、强化科学监管和扶持民营机构等启示对策,以期为推进国有与民营TIC机构做大做强做优以及中国外资TIC机构监管体制机制改革提供参考借鉴。     

北京高校男篮运动员身体训练水平有效因素的研究

在现代运动训练理论中，探索运动员训练水平的有效因素是一个重要的课题。本文对北京高校男篮运动员的各项身体素质进行研究，筛选出影响运动训练水平的有效因子和简便易操作的检查性项目，为教练员更好地控制训练过程提供科学依据。     

论我国知识产权海关保护出口检查制度

由于特定的历史背景,我国知识产权海关保护出口检查制度的立法缺乏实践的积累,并且未有顾及我国经济和利技发展的现实,甚至超越了“世界水平”。立足于我国国情,从最大限度保护权利人利益与维护社会公众利益、保护知识产权与促进国际贸易自由流通两个方面达到平衡来考虑,我国应当在《知识产权海关保护条例》的修改中重点考虑取消现行的出口检查制度。     

全球知识产权研究发展态势与热点分析

基于知识图谱理论,对Web of Science核心数据集收录的1900-2016年间的知识产权相关文献的发文量、发文国家、发文学科、被引文献、关键词等进行可视化分析,研究结果表明：（1）当前知识产权研究处于稳步上升阶段,美国、英国、德国引领全球知识产权发展,中国后发优势明显,从国际合作上看,全球知识产权跨国合作研究匮乏。（2）知识产权研究趋势日趋多样化,知识产权、经济、企业在更宽更广范围内的泛在研究成为主流。（3）知识产权的研究方向主要为知识产权管理与知识产权溢出、知识产权转移与流动、新兴技术知识产权保护、知识产权与跨界资本输入等方面。