氯化镍对家兔离体窦房结自律细胞的影响

目的:探讨氯化镍对家兔窦房结自律细胞的影响.方法:利用细胞内微电极记录技术,观察20例家兔窦房结细胞动作电位以及氯化镍对窦房结细胞动作电位产生的影响.结果:用180μmol/L NiCl2灌流后窦房结自律细胞的VDD、APA、Vmax、RPF均明显下降(P＜0.01),APD、APD90显著延长,MDP、APD50均无明显改变(P＞0.05).结论:氯化镍对窦房结自律细胞的动作电位0相和4相去极离子流有明显的抑制作用.     

氯化锡催化合成丁酸戊酯初探

本文使用氯化锡作为丁酸和戊醇的酯化催化剂。通过L9(3^4)正交实验探讨了回流时间、反应温度、催化剂与酸物质的量比、酸与醇物质的量比等因素对产品丁酸戊酯产率的影响。当n(催化剂)：n(酸)=1：150，n(酸)：n(醇)=1：1、4，在155—160℃下回流搅拌反应2．0h，不使用任何带水剂时；产品丁酸戊酯的产率为83．4％。     

Hypertonic saline resuscitation maintains a more balanced profile of T-lymphocyte subpopulations in a rat model of hemorrhagic shock

Objective： To investigate the potential and early effect of hypertonic saline resuscitation on T-lymphocyte subpopulations in rats with hemorrhagic shock. Methods： A model of rat with severe hemorrhagic shock was established in 18 Sprague-Dawley （SD） rats. The rats were randomly divided into Sham group, HTS group （hypertonic saline resuscitation group） and NS group （normal saline resuscitation group）. Each group contained 6 rats. The CD4~ and CD8~ subpopulations of T-lymphocytes in peripheral blood were detected respectively before shock and after resuscitation by double antibody labelling and flow cytometry. Results： In the early stage after hemorrhagic shock, fluid resuscitation and emergency treatment, the CD4^＋ lymphocytes of peripheral blood in HTS and NS groups markedly increased. Small volume resuscitation with HTS also induced peripheral CD8^＋ lymphocytes to a certain extent, whereas NS resuscitation showed no effect in this respect. Consequently, compared with Sham and HTS groups, CD4^＋/CD8^＋ ratio of peripheral blood in NS group was obviously increased, and showed statistically differences. Conclusion： In this model of rat with severe hemorrhagic shock, small volume resuscitation with HTS is more effective than NS in reducing immunologic disorders and promoting a more balanced profile of T-lymphocyte subpopulations regulating network.     

脱硫系统中碱液及污水氯离子含量的测定研究

主要研究兰州石化公司炼油厂300万/年烟气脱硫装置中碱液及含硫污水中氯离子含量的测定,结合烟气脱硫装置工艺特点,在银量沉淀滴定法（莫尔法）的基础上设计制定了相应的分析方法。拓宽了检测范围,并使用该方法和其他分析方法进行对比,结果表明该方法的准确度较好,可及时准确的配合生产分析。     

Determination of benzalkonium chloride in viscous ophthalmic drops of azithromycin by high-performance liquid chromatography

A high-performance liquid chromatography (HPLC) system was used in the reversed phase mode for the determination of benzalkonium chloride (BKC) in azithromycin viscous ophthalmic drops. A Venusil-XBP(L)-C_(18) (150 mm×4.6 mm, 5 μm) column was used at 50 ℃. The mobile phase consisted of a mixture of methanol-potassium phosphate (16:5, v/v). Two sample preparation methods were compared. The results suggested that, compared with an extraction procedure, a deproteinization procedure was much quicker and more convenient. Using the deproteinization procedure for sample preparation, calibration curves were linear in the range 5.0～50 μg/ml. The within-day and inter-day coefficients of variation were less than 10%. The average recoveries were determined as 96.70%, 98.52%, and 97.96% at concentrations of 10.0, 30.0, and 50.0 μg/ml, respectively. Variability in precision did not exceed 5%. In conclusion, this HPLC method using a simple sample treatment procedure appears suitable for monitoring BKC content in azithromycin viscous ophthalmic drops.     

微波辐射相转移催化合成对甲苯基苄基醚

以水-95%乙醇为溶剂,以氯化苄和对甲苯酚为原料,在相转移催化作用下,利用微波辐射合成对甲苯基苄基醚。实验表明,对甲苯酚、氯化苄、氢氧化钠的摩尔比为1：1.1：1.1,400W下微波辐射反应6min。对甲苯基苄基醚的产率为96.21%。     

生物分子膜仿生合成碱式氯化铜晶体

研究了牛血清白蛋白（BSA）Langmuir单层膜对碱式氯化铜晶体的成核和取向生长的调控作用．利用X射线衍射仪（XRD）和扫描电镜（SEM）等技术对晶体的结构和形貌进行了表征和观察．结果表明,在生物单分子膜诱导作用下,可以获得花生状的碱式氯化铜晶体,且主要沿（110）晶面取向生长．并进一步探讨了生物单层膜在晶体生长上的调控机理．     

氯盐外侵和内掺引起的混凝土内钢筋锈蚀特征的比较研究

氯盐外侵和内掺氯盐是耐久性研究经常采用的两种加速试验方法．通过大量的构件破型发现：氯盐外侵试件中钢筋的锈蚀为靠近混凝土保护层一侧锈蚀比较严重,而背向一侧几乎没有发生;内掺氯盐试件中钢筋的锈蚀特征为钢筋四周均发生锈蚀,靠近混凝土保护层一侧的锈蚀较背向保护层的一侧严重．理论分析和试验研究结果表明混凝土内钢筋锈蚀特征取决于钢筋内外表面的活化状态及钢筋内外表面间宏观腐蚀电流Ig．     

水泥基材料中氯离子表观扩散系数计算方法

通过试验研究了文献中报道的几种依据菲克第二定律的氯离子表观扩散系数计算方法．试验结果表明：不同的计算方法所求的D值有很大差异;北欧标准NT Build443中采用最小二乘法计算表观氯离子扩散系数并不合适,在有些情况下会产生很大的误差;在这几种方法中,将表面氯离子浓度Cs值直接求出,每个深度计算出一个表观扩散系数值Di,然后取平均值计算表观扩散系数D的计算方法更适宜计算氯离子表现扩散系数;而在Cs和D作为常数考虑的情况下,几种计算方法绘制的氯离子浓度分布曲线都与试验数据有一定程度的差异．因此,菲克第二定律在描述氯离子在混凝土中的迁移时,不宜将Cs和D作为崤量考恿．     

赤泥盐酸浸出液制备聚合氯化铝钙的研究

以赤泥盐酸浸出液、NaOH为原料在一定条件下进行反应聚合、干燥制备无机高分子混凝剂-聚合氯化铝钙的研究。结果显示NaOH的加入量为1 mol,PH值为3,反应温度为60℃,较适宜于产品的合成。