ONP脱墨浆的可漂性研究

ONP脱墨浆往往需要进一步漂白。对5种用不同脱墨剂处理的ONP脱墨浆进行了H2O2漂白实验,结果表明不同脱墨剂处理的ONP白度增加幅度不相同,各脱墨浆的可漂性并不相同。实际使用ONP脱墨浆时需考虑其漂后白度增幅潜力。     

Utility of P-SEP,sTREM-1 and suPAR as Novel Sepsis Biomarkers in SARS-CoV-2 Infection

The coronavirus disease 2019 is a highly contagious viral infection caused by SARS-CoV-2 virus, member of coronaviridae family. It causes life threatening complications due to complexity and rapid onset course of the disease. Early identification of high-risk patients who require close monitoring and aggressive treatment remains challengeable till date. Novel biomarkers which help to identify high risk patients at the early stage is high priority. Objective of this review to find utility of P-SEP, sTREM-1 and suPAR for diagnosis, risk stratification and prognosis of SARS-CoV-2 infected cases. Soluble receptors like, P-SEP, sTREM-1 and suPAR have been involved in immune regulation in SARS-CoV-2 infection and elevate more in severe cases. A comprehensive research of databases like PubMed, EMBASE, CNKI and Web of Science was performed for relevant studies. A total of nine out of fifteen research literature in initial screening were included for this review. Interestingly all studies have reported high levels of P-SEP, sTREM-1 and suPAR in SARS-CoV-2 infected cases and the biomarkers positively correlated with severity of infection. This implies that P-SEP, sTREM-1 and suPAR can be implemented as surrogate marker in blood profile for early diagnosis, risk stratification and prognosis in SARS-CoV-2 for better management in Indian population at the current situation.     

下一代数字图书馆系统体系架构的发展动向

文章介绍了国外近年来下一代数字图书馆系统体系架构研究的新动向,着重分析了SOA、网格和P2P技术在数字图书馆领域内应用的研究及所开发的原型系统.     

中国经济空间格局演变及其CO2排放效应

改革开放以来,中国经历了由东部率先发展到区域协调发展的区域战略调整,中国经济空间格局发生较大改变.探究CO2排放量对经济空间格局演变的响应,对中国尽早实现CO2排放达峰目标、确保可持续发展具有重要意义.本文在刻画1985-2017年中国经济空间格局演变特征的基础上,基于LMDI因素分解方法分析了中国CO2排放的驱动因素...     

Combined effects of exposure to hypoxia and cool on walking economy and muscle oxygenation profiles at tibialis anterior

We investigated combined effects of ambient temperature (23°C or 13°C) and fraction of inspired oxygen (21%O₂ or 13%O₂) on energy cost of walking (C_w: J·kg^?1·km^?1) and economical speed (ES). Eighteen healthy young adults (11 males, seven females) walked at seven speeds from 0.67 to 1.67 m s^?1 (four min per stage). Environmental conditions were set; thermoneutral (N: 23°C) with normoxia (N: 21%O₂) = NN; 23°C (N) with hypoxia (H: 13%O₂) = NH; cool (C: 13°C) with 21%O₂ (N) = CN, and 13°C (C) with 13%O₂ (H) = CH. Muscle deoxygenation (HHb) and tissue O₂ saturation (StO₂) were measured at tibialis anterior. We found a significantly slower ES in NH (1.289 ± 0.091 m s^?1) and CH (1.275 ± 0.099 m s^?1) than in NN (1.334 ± 0.112 m s^?1) and CN (1.332 ± 0.104 m s^?1). Changes in HHb and StO₂ were related to the ES. These results suggested that the combined effects (exposure to hypoxia and cool) is nearly equal to exposure to hypoxia and cool individually. Specifically, acute moderate hypoxia slowed the ES by approx. 4%, but acute cool environment did not affect the ES. Further, HHb and StO₂ may partly account for an individual ES.     

Replication,pathogenicity, and transmission of SARS-CoV-2 in minks

Minks are raised in many countries and have transmitted severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to humans. However, the biologic properties of SARS-CoV-2 in minks are largely unknown. Here, we investigated and found that SARS-CoV-2 replicates efficiently in both the upper and lower respiratory tracts, and transmits efficiently in minks via respiratory droplets; pulmonary lesions caused by SARS-CoV-2 in minks are similar to those seen in humans with COVID-19. We further found that a spike protein-based subunit vaccine largely prevented SARS-CoV-2 replication and lung damage caused by SARS-CoV-2 infection in minks. Our study indicates that minks are a useful animal model for evaluating the efficacy of drugs or vaccines against COVID-19 and that vaccination is a potential strategy to prevent minks from transmitting SARS-CoV-2.     

Bcl-2基因家族及子宫内膜增生、癌变研究综述

目前已发现数个Bcl-2基因家族成员。主要有Bcl-2、Bax等，它们调节子宫内膜细胞的凋亡，与子宫内膜增生、癌变有密切联系。     

利用DOI识别科技期刊官方网站的意义与方法

摘 要 【目的】保证科技期刊官方网站的有效识别与永久链接,扩大官网的网络影响力,为解决非法网站假冒期刊官网、欺骗作者、读者的问题提供途径。【方法】 利用DOI标准与技术以及中文DOI相关服务,对期刊网站进行DOI唯一标识的注册,并通过DOI解析实现方便、持久的网络链接;利用纸刊印刷二维码等方式实现纸刊与期刊网站的连接。【结果】 有效防御假冒伪劣期刊网站对正规网站的侵害;实现科技期刊多种传播渠道的协同增效作用。【结论】 为期刊网站注册DOI标识保护了读者、作者和期刊编辑出版单位的权益,扩大了科技期刊官方影响力,应大力推广。     

面向智能制造的汽车企业c2B模式实施策略

基于新技术条件下汽车产业形态的变化趋势,分析汽车产业走向c2B模式的必然性。根据汽车产业c2B模式的发展过程特征,对其作初级、中级、高级3个不同阶段的划分,并分析该模式对汽车全生命周期各环节的影响;通过对比汽车企业c2B模式的理想状态与现实状况,总结汽车企业c2B模式的关键实现环节,并进一步归纳整车厂和零部件企业需要满足的条件。从汽车产业c2B模式与智能工厂相互交融、互为支撑的关系,分析面向智能制造进行c2B模式建设所需的硬件、软件工作;以典型整车企业为例,提出汽车企业面向智能制造进行c2B模式升级的实施策略。     

中国碳排放区域格局变化与减排途径分析

作为世界能源消费大国,中国的碳排放问题不仅体现在总量增长方面,而且也体现在碳排放的空间格局变化方面。从大区地域系统变化来看:东部地区的碳排放始终在全国占据着主导地位;中部地区碳排放在全国的比重表现出稳中有降的态势;西部地区比重虽较小,但基本保持着上升趋势。从省(区、市)级变化来看:1953年以来,碳排放的区域差异不断增大,并且其变化可以分为3个阶段:1952年为起始阶段、1953年-1980年为初级分化阶段、1981年-2005年为快速演进阶段。本文试图通过产业-能源关联和能源-碳排放关联两个基本评价模型,解析中国碳排放区域格局变化的原因。分析结果表明:①产业结构的演进决定着一次能源消费的基本空间格局;②地区产业结构多元化程度越是走向成熟,其一次能源消费的增速也就越是减缓;③缓慢的一次能源消费结构变化是难以降低地区碳排放增长的关键所在。因此,加快产业结构演进速率以逐步减缓地区一次能源消费总量增长,以及最大限度地改善各地区、特别是东部地区的一次能源供应结构,是有效控制区域碳排放增长的关键。