Diagnostic Dilemma of HbA1c Detection in Presence of a Hemoglobinopathy: A Case Report

We report a case of a diabetic, heterozygote with near normal hematology, marginally low level of hemoglobin A₂(HbA₂) having an increased level of hemoglobin F(HbF) that was pancellularly distributed among the red cells. BioRad DiaSTAT measurements gave a high glycated hemoglobin A1c(HbA1c) of 31.5% and the BioRad Variant analyzer recorded an HbA1c value which was very low, in discordance with the detected blood glucose levels. Flow cytometry and polymerization chain reaction (PCR) based studies were carried out which revealed the case to be that of the common hereditary persistence of fetal hemoglobin (HPFH)-3, an Asian Indian mutation. Fructosamine estimation and HbA1c by Boronate affinity chromatography were able to resolve the discordant value detected and was able to confirm the diabetes status. The case would have been a diagnostic dilemma, if reported without correlation.     

聚合硫酸铁的制备工艺改进

采用过氧化氢作为氧化剂制备聚合硫酸铁,探讨了硫酸用量、过氧化氢用量、反应温度这三个反应条件对产品各项质量指标的影响。结果表明,当硫酸与硫酸亚铁的摩尔比在0.31～0.41之间,过氧化氢与硫酸亚铁的摩尔比为2∶1,反应温度控制在20～35℃之间,制备所得的聚合硫酸铁的各项质量指标均符合国家标准。     

Reducing suspension for minor infraction and improving school climate perceptions among black adolescents via cultural socialization: A multi-informant longitudinal study

Racially disparate school disciplinary practices create inequitable circumstances for minority and immigrant youth around the world. In the U.S., Black youth are more likely than their White peers to be suspended for minor, non-violent infractions. This study explores (a) whether school cultural socialization practices reported by Black students (N = 544; M_age (SD) = 12.45 (1.57); 49% boys) and teachers (N = 38; 84% female) were linked to a reduced likelihood of receiving suspensions for minor infractions and (b) the extent to which Black students' perceptions of school climate mediated this relation. Results indicated that school cultural socialization was linked to a decreased likelihood of being suspended for a minor infraction and improved school climate perceptions for Black students. Black students’ perception of school climate mediated the link between school cultural socialization and suspensions for minor infractions. These results highlight school cultural socialization as a promising approach for increasing cultural responsivity and equity within schools, reducing racial bias, and expunging unjust disciplinary responses.     

低分子量聚丙烯酰胺的合成研究

以丙烯酰胺为聚合单体,过硫酸铵为引发剂,甲酸钠为链转移剂,采用水溶液聚合法制备了低分子量(105~106)的聚丙烯酰胺。由此探讨了单体浓度、引发剂浓度、链转移剂用量、反应温度和反应时间等因素对产物分子量的影响。     

对苯二酚在聚苯胺纳米纤维修饰电极上的电化学行为研究

采用界面法合成聚苯胺纳米纤维,并利用SEM、TEM、FTIR、XRD表征聚苯胺的表面形貌和结构。将合成出的聚苯胺纳米纤维滴涂在玻碳电极表面制备聚苯胺修饰电极,采用循环伏安法研究对苯二酚在聚苯胺修饰电极上的电化学行为。结果表明,与裸电极相比,对苯二酚在修饰电极上的氧化还原峰电流均增大,峰电位差ΔEp减小了115mV,对苯二酚电化学可逆性得到明显改善,说明修饰电极对对苯二酚的氧化过程有明显的电催化效果。且当对苯二酚在1.0×10-7-1.0×10-3mol/L浓度范围内,其氧化峰电流与浓度之间呈良好线性关系,其相关系数是0.9988,检出限为6×10-8mol/L。     

论皮浪的怀疑主义

皮浪通过＂悬置判断＂的方法,既不肯定判断也不否定判断,达到一种中立的状态,而不断地从事探究。随着＂悬置判断＂获得一种心灵的宁静境界,最终则是肉体的无痛苦和心灵的无纷扰的人生的幸福。皮浪处在动荡不安的社会环境中,并以怀疑主义去反对当时的种种独断论,都有着对人的深切关怀并都想获得一种宁静的心理体验。     

基于层次分析法的大跨径缆索承重桥梁状况评估方法

针对大跨径缆索承重桥梁的特点,制定了一般性评估模型。首先,利用层次分析法建立了大跨径悬索桥和斜拉桥一般性评估递阶层次模型,该模型包括部位层、构件层和损伤层三个层次,随后利用专家调查和群组决策算法确定了部位层和构件层各元素的权重。其次,为了建立损伤层各元素的权重,建立了一种称为动态调权法的权重计算公式。该方法能够较为全面地考虑大跨径缆索承重桥梁的特点,综合反映桥梁的技术状况。     

三软高瓦斯煤层煤巷快速掘进综合防突技术

针对三软高瓦斯煤层瓦斯地质特征和煤巷快速掘进防突需要,采取超前释放瓦斯钻孔、超前卸压控制钻孔、巷帮挂耳抽放以及煤层高压注水等综合防突措施,加强突出预测和效果检验,钻孔瓦斯涌出初速度q的最大值由12L/min下降到2L/min;钻屑量△h2的最大值由300Pa下降到150Pa,月掘进速度达到80m以上。     

铂微粒修饰碳纳米管-纳米TiO2/聚苯胺复合膜电极对抗坏血酸的电催化氧化

采用循环伏安法,在含有0.2mol.L-1苯胺的0.5 mol.L-1的硫酸溶液中,以50mv.s-1的扫描速度,在-0.1~0.9V范围内实现苯胺在碳纳米管-纳米TiO2膜电极上的电化学聚合,得到翠绿色的聚苯胺膜,并用交流阻抗谱对复合膜的电化学性质进行了表征。在该电极上修饰铂,制得铂微粒修饰聚苯胺复合膜电极,研究了其对抗坏血酸的电催化氧化,发现修饰后的电极对抗坏血酸的氧化有很高的催化活性。     

均配型三苄基稀土配合物的合成及在催化L-丙交酯聚合中的应用

聚丙交酯是一类可生物降解的脂肪族聚酯,而且降解产物无毒。丙交酯开环聚合是合成聚丙交酯的一种方便的方法。在无水无氧的条件下,参照文献合成了两种三苄基稀土配合物,它们可以有效地催化L-丙交酯的开环聚合,中心金属离子半径对催化效果有一定影响,并通过对齐聚物末端基的分析,得出了开环聚合物的机理与文献报道一致。