MPEG标准的发展及应用

描述了MPEG所推出的一系列标准,并对标准的内容和实际应用作了简要介绍.     

3-(6-溴吡啶-2)-2-(2-氟-6-氯苯)-噻唑酮-4的电子结构与抗HIV活性间关系的量子化学研究

采用AM1方法,对3-(6-溴吡啶-2)-2-(2-氟-6-氯苯)-噻唑酮-4(BPFCTZO)进行了量子化学计算,给出了分子的几何构型、原子的净电荷、键级、前沿分子轨道组成与能级、前沿轨道电子密度等参数.结果表明BPFCTZO分子的稳定构型呈蝴蝶状,噻唑酮环为主活性区,其上的2位C、4位N和6位O等原子很可能是其与RT酶作用的活性位点.     

高师文科学报学术优势刍议

高校科学报的学术质量与高师的学科建设关系密切。学报的学术优势有赖于学校的学术优势。这种优势具有客观性、被动性、局限性、互动性。必须有“优势”意识：正视优势，准确把握，精心经营；以显现优势，办出特色，提高质量。     

加强学科建设 实现跨越式发展

黑龙江科技学院矿物加工学科面向区域经济，突出矿业特色，提升实验条件，研发科技成果，建设成黑龙江省级重点学科，实现了学科建设的跨越式发展。     

L-fuzzy相对T-1,相对T0与相对次T0分离性

定义了L-fuzzy拓扑空间中的相对T-1，相对T0与相对次T0分离性，讨论了相对T-1，相对T0与相对次T0分离性的一系列性质．证明了相对T-1，相对T0与相对次T0分离性是遗传的、传递的、弱同胚不变的及可乘性等性质，并给出了一些例子。     

关于多项式唯一性问题

推广了Adams-Straus关于多项式唯一性的一个定理，得到结果：设p与q皆为非常数的多项式，a1，a2，…，ak及b为k＋1个互异有穷复数，若↑k∏↓i=1（p-ai）=0〈=〉q-b=0，并且有d[↑k∏↓i（z-ai）]/dx｜x=b≠0，则p≡q。     

合成草莓酯的新型催化剂

综述了无机盐、无机酸、杂多酸(盐)、固体超强酸等催化剂催化合成草莓酯的实验情况.结果表明,硫酸铝、CuCl2 ·2H2 O、固体超强酸SO2 -4 -TiO2 /Al2 O3、活性炭固载硅钨酸等催化剂催化合成草莓酯的收率较高,具有一定的工业应用价值.     

R&D co-operation and innovation a microeconometric study on French firms

The scope of this paper is to report new empirical evidence on the determinants of R&D co-operation. Indeed, the literature on the capabilities of firms emphasises the role of knowledge in the performance and evolution of firms who use knowledge developed in others to build their own knowledge capital. R&D co-operation between firms is one of the many strategies by which this knowledge may be transmitted. Several theoretical models have stressed that R&D co-operation is more likely when the level of spillovers is high. While this supposition is used in many theoretical models, it has rarely been tested before. Our results do not lend strong support to this intuition. Indeed, our spillover variables (national pure spillovers, national rent spillovers and imports of machine tools), which were supposed to match the theoretical notion of spillovers used in these theoretical models have a positive but not a significant role when explaining R&D co-operation. The R&D co-operation increases with size and with R&D intensity, but not with market share. It also increases with the budget spent on paying license fees and on acquiring patents and labour from foreign firms. In this study, we also analyse the determinants of innovation. In more precise terms, we compare the effects of R&D co-operation to those played by traditional internal factors and those exerted by external, pure and rent spillovers on the innovation capacity of the firms. Our results show that the commercial success of innovations of French firms depends mainly on size, market share, R&D intensity and human capital. Inward FDI from industrialised countries exerts a positive and significant effect. The finding highlights the important role of the absorptive capacity of firms. Spillover measurements, such as the acquisition of machine tools, foreign patents, licenses, and technological opportunities have a positive impact on innovation.     

Expression of antimicrobial peptide Cecropin P1 in Saccharomyces cerevisiae and its antibacterial and antiviral activity in vitro

BackgroundCecropin P1, acting as an antimicrobial, has a broad-spectrum antibacterial activity with some antiviral and antifungal properties. It is a promising natural alternative to antibiotics which is originally isolated from the pig intestinal parasitic nematode Ascaris suum. Many studies have shown that Cecropin P1 is helpful for the prevention or treatment of clinical diseases. Therefore, it is very necessary to establish a safe, nontoxic, and efficient expression method of Cecropin P1.ResultsThe results indicated that the recombinant protein was about 5.5 kDa showed by Tricine–SDS–PAGE and Western blot. And Cecropin P1 was efficiently secreted and expressed after 12 h of induction, with an increasing yield over the course of the induction. Its maximum concentration was 7.83 mg/L after concentration and purification. In addition, in vitro experiments demonstrated that Cecropin P1 not only exerted a strong inhibitory effect on Escherichia coli, Salmonella sp., Shigella sp., and Pasteurella sp., but also displayed an antiviral activity against PRRSV NADC30-Like strain.ConclusionsCollectively, the strategy of expressing Cecropin P1 in Saccharomyces cerevisiae is harmless, efficient, and safe for cells. In addition, the expressed Cecropin P1 has antiviral and antibacterial properties concurrently.How to cite: Jiang R, Zhang P, Wu X, et al., Expression of antimicrobial peptide Cecropin P1 in Saccharomyces cerevisiae and its antibacterial and antiviral activity in vitro. Electron J Biotechnol 2021;50. https://doi.org/10.1016/j.ejbt.2020.12.006     

“大学域” 图书馆资源共享研究

随着高等教育规模的扩大，大学城在我国得到了迅速的发展。文章分析了大学城在我国产生的必然性，大学城资源共享的主要领域，提出了大学城图书馆之间可以在政策制定、协调采购、目录编制、馆际互借、对外交流和利用现代信息技术方面实现资源共享，分析了在资源共享方面存在的问题。