预防痢疾莫放松

每年春夏之交,是痢疾杆菌大肆活动的时节.由痢疾杆菌引起的急性肠道传染病,简称痢疾.痢疾是以腹部疼痛、里急后重、下赤白脓血便为主要症状的肠道传染性疾病.该病主要通过病人或带菌者的粪便污染水、食物、手进行传播;苍蝇往来于粪便、饮料、食物之间,也加快了痢疾的传播.营养不良、患有肠道寄生虫病等身体虚弱者,容易患该病.痢疾临床可分为急性、慢性两类,病程超过2个月者为慢性细菌性疾病.     

儿童急性呼吸道感染中流感嗜血杆菌的检测与分型

目的 :为了解儿童急性呼吸道感染中的流感嗜血杆菌与生物分型及其对抗生素的敏感情况。方法 :对 78例急性呼吸道感染儿童采用常规方法进行了培养 ,药敏试验与生物分型。结果 :共分离出流感嗜血杆菌 33株 ,检出率为 4 2 .3% ,在对所有分离株进行的生物分型结果中 ,共检出 5型 ,其中以Ⅳ ,Ⅵ型居多 ,分别为Ⅳ型 8例 (2 4 .2 % ) Ⅵ型 13例 (39.4 % )。 33株分离出的流感嗜血杆菌中 ,全部菌株对氯霉素 ,氧氟沙星敏感 ,头孢拉定株 2 1(6 3.6 % ) 、头孢唑林 19株 (5 7.6 % )、去甲万古霉素 2 3株 (6 9.7% ) 、苯唑青霉素 31株 (93.4 % ) 、复方磺鞍甲基异唑 11株 (33.3% )、红霉素 4株 (13.2 % )。结论 :儿童急性呼吸道感染中流感嗜血杆菌有较高的检出率 ,以生物Ⅵ型和Ⅳ型居多。流感嗜血杆菌存在着严重的耐药倾向。     

中药副作用不容忽视

多年来，“中药副作用少”的说法，使人们对某些中草药的肾毒性缺少足够的认识和重视。20世纪90年代中期，比利时医生首先发现，相当数量的“肥妞”、“胖嫂”在无所禁忌地服用减肥中药后发生急性肾衰，由此提出了“中药肾病”的概念。近几年，因滥服中草药导致肾炎和急性肾功能衰竭的病人日趋增多。专家为此呼吁：必须提高人们对中草药肾毒性的认识。     

隔姜灸加超短波治疗急性细菌性痢疾31例临床观察

笔者于1997～2000年间运用隔姜灸配合超短波,治疗急性细菌性痢疾31例,取得了较满意的疗效,现报告如下:     

谨防小儿脓疱疮诱发肾炎

脓疱疮俗称黄水疮,是一种常见的由化脓性球菌引起的急性炎症皮肤病,具有接触传染特征。脓疱疮90%以上见于儿童,以1-4岁为高发年龄,症见皮肤上发生小红疹子、水疱或脓汁沉于疱底、呈半月型积脓状的大疱、脓疱,疱易破溃,流黄水,结脓痂,患儿自觉瘙痒,一般无全身症状。由于接触传染     

Cell therapy in congestive heart failure

Congestive heart failure （CHF） has emerged as a major worldwide epidemic and its main causes seem to be the aging of the population and the survival of patients with post-myocardial infarction. Cardiomyocyte dropout （necrosis and apoptosis） plays a critical role in the progress of CHF; thus treatment of CHF by exogenous cell implantation will be a promising medical approach. In the acute phase of cardiac damage cardiac stem cells （CSCs） within the heart divide symmetrically and/or asymmetrically in response to the change of heart homeostasis, and at the same time homing of bone marrow stem cells （BMCs） to injured area is thought to occur, which not only reconstitutes CSC population to normal levels but also repairs the heart by differentiation into cardiac tissue. So far, basic studies by using potential sources such as BMCs and CSCs to treat animat CHF have shown improved ventricular remodelling and heart function. Recently, however, a few of randomized, double-blind, placebo-controlled clinical trials demonstrated mixed results in heart failure with BMC therapy during acute myocardial infarction.     

Effect of a distal protection device on epicardial blood flow and myocardial perfusion in primary percutaneous coronary intervention

Objective: The beneficial effect of percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (AMI) has been well established, but there is the problem of no-reflow phenomenon which is an adverse prognostic factor in primary PCI. In the present study the effect of a distal protection device (PercuSurge GuardWire; GW) on epicardial blood flow and myocardial perfusion was evaluated. Methods and Results: Patients with AMI were randomly divided into 2 groups, the GW and the control groups. The GW group included 52 patients with AMI who underwent primary PCI with GW protection and the control group included 60 patients who underwent primary PCI without GW protection. Epicardial blood flow in the infarct-related artery (IRA) and myocardial perfusion were evaluated according to the thrombolysis in myocardial infarction (TIMI) flow grade and the myocardial blush grade (MBG). We found TIMI score of 3 was obtained significantly more frequently in the GW group (96%) than in the control group (80%). The MBG score of 3 was obtained also significantly greater in the GW group (65%) than in the control group (33%). Conclusion: Primary PCI with GW protection can significantly improve epicardial blood flow and myocardial perfusion.     

可悲的“价值实现”

一位同事的就读于北京大学的女儿突然查出了急性白血病,得悉这一消息大家无不忧心如焚,纷纷献计献策,捐钱捐物。另有一名同事的孩子正读高三,闻讯后抛出了一句让大伙儿谁也意     

西藏地区表现为Opalski综合征的急性缺血性脑卒中

目的 总结Opalski综合征的诊治经验,提升临床对该疾病的诊治效率。方法 详细分析1例高原地区发生的Opalski综合征的临床、检验和影像学资料,并结合文献检索总结33例特点。结果 33例患者中发病年龄在26～86岁之间,男性22人,占比66%,女性11人,占比33%.临床表现中为偏瘫100%、感觉障碍78%、眩晕66%、恶心呕吐45%,被发现的体征中Horner征48%、babinski(+)39%、眼震21%.影像学表现中延髓及高颈段梗死81%,小脑、枕叶梗死占27%,PICA或椎动脉闭塞或狭窄54%,椎动脉夹层12%.结论 Opalski综合征常表现为偏瘫、感觉障碍、眩晕、恶心呕吐等症状,体征中常见Horner征、眼震等,并非所有患者都存在babinski（+）,在临床工作中需注意相关临床特点,早期识别并给予血管再通治疗。