A case of vitamin B12 deficiency neurological syndrome in a young adult due to late-onset cobalamin C (CblC) deficiency: a diagnostic challenge

Vitamin B12 deficiency can present with neurologic and psychiatric symptoms without macrocytic anaemia. We describe a case of late-onset cobalamin C deficiency which typically presents with normal serum vitamin B12 concentrations, posing an additional diagnostic challenge. A 23-year-old woman with decreased muscle strength and hallucinations was diagnosed with ‘catatonic depression’ and admitted to a residential mental health facility. She was referred to our hospital for further investigation 3 months later. Heteroanamnesis revealed that the symptoms had been evolving progressively over several months. Magnetic resonance imaging (MRI) of the brain showed diffuse symmetrical white matter lesions in both hemispheres. Routine laboratory tests including vitamin B12 and folic acid were normal except for a slight normocytic, normochromic anaemia. Over the next 6 weeks her symptoms deteriorated, and she became unresponsive to stimuli. A new MRI scan showed progression of the white matter lesions. The neurologist requested plasma homocysteine (Hcys) which was more than 8 times the upper limit of normal. Further testing revealed increased methylmalonic acid and the patient was diagnosed with adult-onset cobalamin C deficiency. This case illustrates that Hcys and/or methylmalonic acid should be determined in patients presenting with neuropsychiatric symptoms suggestive of vitamin B12 deficiency with a normal serum vitamin B12 to rule out a late-onset cobalamin C deficiency.     

Fiḍḍa l-Nūbiyya: The Woman and her Role in Early Shīՙite History

The purpose of the present study is to analyse the role played by an important female figure in early Shī?ite history. The person in question is Fi[ddot][ddot]a l-Nūbiyya, the servant-girl of Fā ?ima, the Prophet's daughter. After a long period of neglect by scholars, who have focused on what to their mind were figures of greater import, we shall here attempt to describe the role played by Fi[ddot][ddot]a in early Shī?ite history by way of analysing her biography and her close relations with Fā ?ima and members of the latter's family (?Alī, [Hdot]asan and [Hdot]usayn). We shall further describe what has been reported of Fi[ddot][ddot]a's personality, her family, her admiration for the Prophet's family, Qur?ānic verses which supposedly mention her, and the great respect in which she was held by Fā ?ima's family.     

关于企业铁路C62A型号货车增载的可行性探讨

随着国民经济的发展,铁路车辆的需求矛盾日益突出,从增加运输能力的角度考虑,对现有的车辆进行增载是一个投资少、见效快的途径,根据企业铁路目前使用的C62A型车辆的主要技术参数及状况,从垂直动载荷及技术指标分析,在标记载重60t的基础上增重5t是可行的,并能产生较大的经济效益,可以在企业铁路上进行推广。     

C/S结构与B/S结构的信息系统比较分析

传统的C/S体系结构虽然采用的是开放模式。但这只是系统开发一级的开放性，在特定的应用中无论时Client端还是Server端都还需要特定的软件，没有提供用户真正期望的开放环境。B/S结构则不同，它的前端是以TCP/IP协议为基础的，企业内的WWW服务器可以接受安装有Web浏览器，各种处理任务都可以调用系统资源来完成。这样大大简化了客户端。减轻了系统维护与升级的成本和工作量，降低了用户的总体拥有成本（TCO）。     

富勒烯C60,C70的发现与研究

介绍了C60，C70的发现过程，并且较系统地综述了当前对它们的物理性质和化学性质的研究．     

木防己多糖的组成及其清除活性氧自由基的作用

目的:提取并纯化木防己多糖(AFMP),确定其组成,研究其清除活性氧自由基的作用.方法:利用水提醇沉得到木防己粗多糖,再经DEAE纤维素和聚酰胺纯制.利用Fenton反应研究AFMP清除·OH的作用;利用邻苯三酚自氧化法研究AFMP清除·O2-的作用.结果:纸色谱显示AFMP由葡萄糖和半乳糖组成.AFMP清除·OH的能力较弱;清除·O2-时的效果稍强,IC50为1407.4μg/ml.结论:木防己多糖为首次提取制得,有一定的清除羟自由基和超氧阴离子自由基的作用.     

基于C8051F121和XSZ的无线电罗盘角度测量的设计

为解决飞机无线电罗盘输出角度信号的测量问题,设计了基于C8051F121和旋转变压器——直流电压转换器（XSZ）的测角仪。介绍了旋转变压器、旋转变压器——直流电压转换器的结构和原理,软件中航向角度的算法。     

C4.5决策树算法在应用型本科高校就业管理中的应用研究

将数据挖掘中的C4.5算法应用于应用型本科院校的就业管理信息系统中,有利于发掘出应用型毕业生就业中隐藏的有用因素和内在联系,对促进学校进行教学改革,指导学生提高自身素质和知识结构,从而最大程度的提高毕业生的就业率。     

应用模糊C均值聚类法判别同调机群正确性研究

利用BPA软件以新英格兰10机39节点系统为例,验证模糊C均值聚类法判别同调机群的正确性。     

Kinship,Camaraderie and Contestation: Fāṭimid Relations with the Ashrāf in the Fourth/Tenth Century.

The founding of the Fā?imid caliphate across the southern Mediterranean, and then in Egypt, Syria and the ?ijāz at the turn of the fourth/tenth century, necessitated its negotiation with the ashrāf, those who claimed lineal descent from the Prophet Mu?ammad, and who by this time had gained significant influence as a social class based on their charismatic descent. While other dynastic powers fostered relationships with various members of the ashrāf, the Fā?imid–ashrāf dynamics were distinctive in that the Fā?imids legitimised their rule as Ismā?īlī Shī?ī imām-caliphs, based on their claim of descent from the Prophet Mu?ammad, and as the sole successors to his authority and leadership over the Islamic world. Consequently, Fā?imid–ashrāf relations were permeated by fraternal camaraderie as well as by competing contestations based on their shared claim to Prophetic lineage.