A study of women's compliance‐gaining behaviors in violent and non‐violent relationships

Recent research by communication scholars has investigated the dynamics of abusive spousal relationships (Chandler, 1986; Infante, Chandler, & Rudd, 1989; Infante, Chandler‐Sabourin, Rudd, & Shannon, 1990; Rancer & Niemasz, 1988; Rudd, Burant, & Beatty, 1994; Sabourin, Infante, & Rudd, 1993). Infante and his colleagues have suggested that those involved in violent relationships communicate differently with their partners than those involved in nonviolent relationships. Based on this prior research, it seems important for communication scholars to further investigate the communication behaviors of individuals involved in violent relationships. This current study seeks to advance the family violence research by comparing the types of compliance‐gaining strategies that battered and non‐battered women report using during their disputes.     

“Kind,Sensitive, and Above All,Honest”: Long-Term Cancer Survivors’ Quality of Life and Self-Advocacy

ABSTRACT

Long-term survivors of cancer (LTS) are a growing population whose needs differ significantly from patients undergoing cancer treatment. Many LTS suffer from late effects of cancer treatments or symptoms that persist after treatment concludes or appear following remission. This study explored the relationship between LTS perceptions of quality of life with late effects and perceptions of patient self-advocacy through quantitative and qualitative analyses. A negative statistical relationship emerged between the variables. LTS median self-advocacy scores were quite high, reflecting their preference for health-care providers who listen actively, understand patient needs, are knowledgeable and compassionate, and utilize joint decision making.     

Patterns of Social Support Communicated in Response to Expressions of Uncertainty in an Online Community of Young Adults with Cancer

In order to develop more effective ways of helping adolescents and young adult (AYA) cancer survivors cope with cancer-related uncertainty, it is important to understand how AYAs respond communicatively to each other's uncertainty. We designed this project to gain insight into the patterns of social support that occur in response to AYAs' expressions of uncertainty. We analyzed 510 responses to posts in an AYA-focused online discussion group. Eighty-two percent of messages responding to uncertainty contained informational support. Sixty-seven percent contained multiple types of support. Among medical, personal, and social sources of uncertainty, the most typical response tended to be a combination of informational support accompanied by emotional and/or esteem support. AYAs who express uncertainty in online support groups should be advised that their posts are likely to be met with information, such as advice and referrals, which may either facilitate or impede their uncertainty management goals.     

Uncertainty and previvors’ cancer risk management: understanding the decision-making process

Women who test positive for a BRCA genetic mutation, but who have not been diagnosed, or 'previvors,' experience intense, chronological risk-related uncertainty. Women’s risk management medical decisions can be a way to manage their uncertainty, but little is known about how uncertainty informs their decision or how uncertainty is impacted by these medical decisions. Using an uncertainty management theoretical lens, we interviewed 46 previvors about their decision-making process. A thematic analysis revealed two uncertainty management (i.e., risk-reducing) decision-making pathways (preventive surgery and increased surveillance) with each pathway encompassing a three-part process of 1) uncertainty appraisal, 2) medical decision (i.e., uncertainty management strategy), and 3) outcomes. The findings advance theoretical thinking about uncertainty and risk management as an ongoing, distressful chronic experience, and highlight the importance of life-span phenomena in women’s decision-making process. Based on the findings, we constructed a translational tool to aid genetic counselors and previvors facing these medical decisions.     

Vitamin C in Disease Prevention and Cure: An Overview

The recognition of vitamin C is associated with a history of an unrelenting search for the cause of the ancient haemorrhagic disease scurvy. Isolated in 1928, vitamin C is essential for the development and maintenance of connective tissues. It plays an important role in bone formation, wound healing and the maintenance of healthy gums. Vitamin C plays an important role in a number of metabolic functions including the activation of the B vitamin, folic acid, the conversion of cholesterol to bile acids and the conversion of the amino acid, tryptophan, to the neurotransmitter, serotonin. It is an antioxidant that protects body from free radical damage. It is used as therapeutic agent in many diseases and disorders. Vitamin C protects the immune system, reduces the severity of allergic reactions and helps to fight off infections. However the significance and beneficial effect of vitamin C in respect to human disease such as cancer, atherosclerosis, diabetes, neurodegenerative disease and metal toxicity however remains equivocal. Thus further continuous uninterrupted efforts may open new vistas to understand its significance in disease management.     

Intensity of lifetime physical activity and breast cancer risk among Polish women

Abstract

Physical activity is associated with a lower risk of breast cancer, although research findings are inconsistent regarding the type, duration, intensity, and frequency of activities that are necessary to reduce the risk, as well as dependence on menopausal status. To address these issues, I examined the effect of physical activity on breast cancer risk among 858 Polish invasive breast cancer cases and 1085 controls. Data on components of lifetime household, occupational, and recreational activities were collected in 2003–2007, using a self-administered questionnaire. Odds ratios with 95% confidence intervals were estimated using unconditional logistic regression analyses and a full assessment of confounding variables. For all types of physical activity, odds ratios were calculated for self-reported and compendium-based assigned levels of activity. Moderate- and vigorous-intensity total and recreational activities, as well as moderate- and long-lasting low-intensity household activities, lowered the risk by at least 44% for the highest versus lowest quartiles of activity in both menopausal groups. The associations were linear (P_trend≤ 0.009). There was a suggestion of a risk reduction for occupational activity among post-menopausal women. These findings show that a risk reduction can be achieved by vigorous-intensity activities or by longer-lasting activities of moderate-intensity.     

蛙泳基本技术MMCAI课件的研制

结合现代教育技术理论 ,开发研制出符合游泳教学特点 ,图、文、声、像、动并茂的多媒体教学软件 ,以弥补游泳传统教学手段的不足和填补了国内体育术科教学CAI课件的空白     

Roles and molecular mechanisms of physical exercise in cancer prevention and treatment

Exercise can enhance motivation to change lifestyle behaviors, improve aerobic fitness, improve physical function, control fatigue, and enhance quality of life. Studies have demonstrated the benefits to be gained from physical exercise, highlighting the importance of popularizing the concept of physical exercise for individuals and making professional exercise-treatment programs available to patients with cancer. However, the correlation between physical exercise and carcinogenesis is easily overlooked, and exercise interventions are not routinely provided to patients with cancer, especially those with advanced cancer. In this article, we present a literature review of the effects of exercise on cancer development and progression and give recent evidence for the type of exercise best suited for different types of cancer and in different disease stages. Moreover, the molecular mechanisms about regulating metabolism and systemic immune function in cancer are summarized and discussed. In conclusion, physical exercise should be considered as an important intervention for preventing and treating cancer and its complications.     

基质金属蛋白酶-2在乳腺癌中的表达及与侵袭、转移的关系

[目的]探讨乳腺癌细胞基质金属蛋白酶-2的表达及其与侵袭、转移的关系.[方法]免疫组织化学方法检测60例乳腺癌患者癌组织中MMP-2表达.[结果]MMP-2的表达在乳腺癌细胞明显高于正常乳腺细胞(P<0.01);淋巴结转移组明显高于非淋巴结转移组(P<0.01);在中、低分化组明显高于高分化组(P.<0.01).但与组织学类型无关(P<0.05).[结果]乳腺癌的MMP-2的表达与其侵袭、转移可能相关.     

细胞质lncRNAs与肿瘤信号调控（英文）

恶性肿瘤疾病长期作为危害人类健康的重要隐患,目前针对重要信号调控通路的一系列靶向抑制剂在临床后期业已出现耐药现象,迫切要求人们在肿瘤生物学研究和靶向治疗方向不断寻找新的可替代性靶点。长链非编码RNAs(lnc RNAs)作为最新关注的研究热点,其在肿瘤发生和转移中的重要调节功能不断被我们及相关学者重点报道。随着RNA通量深度测序等相关研究技术的推广和发展,使人们得以饱览赏析lnc RNAs作为健康和疾病重要调节因子的宏观图谱。本综述总结了胞质lnc RNAs在调节肿瘤重要信号通路中的研究进展及其在肿瘤发生发展中的作用,为癌症的预前预后和靶向治疗提供帮助。