田径运动消减与我国青少年体质下降的关系及对策

我国青少年体质20年持续下降是一个严重的问题,心肺血管功能差是致命的弱点,学校的应试教育是主要原因.因学生体质差怕出伤害事故而消减田径运动,因田径运动消减而造成学生心肺血管功能差,两者互为因果,形成恶性循环.将男生1 000m跑、女生800m跑直接列入中考和高考,从根本上冲破传统观念的束缚,以扭转青少年体质持续下降的状...     

瑜伽意念呼吸练习对肺通气和肺活量的影响

呼吸是瑜伽练习的精华和关键,瑜伽呼吸与其他运动项目的呼吸不同,是由意念来调控的。本文分析了瑜伽意念呼吸特点以及瑜伽意念呼吸练习对肺通气和肺活量的影响。     

结核分枝杆菌MTB8.1蛋白自诱导发酵研究

目的：初步摸索出一条适合工业化开发、高效的、可溶表达结核分枝杆菌MTB8.1蛋白的发酵工艺。方法：利用菌株pUC18/MTB8.1/DH10B为发酵株,通过对培养基组成和发酵参数进行系统研究,从而获得一全新的发酵工艺。结果：重组结核分枝杆菌MTB8.1蛋白通过本发酵工艺的表达,单位体积发酵液可溶性蛋白的产量大幅提高,每升发酵液纯化得到可溶性蛋白约30 mg左右。结论：初步摸索出一条较好的MTB8.1在大肠埃希菌系统中的可溶性表达的途径,为其工业化生产奠定了理论基础。     

Analysis of SEVA TB ES-31 antigen specific immunoglobulins IgM, IgA and IgG in sera of sputum and culture positive pulmonary tuberculosis

Tuberculosis remains major health problem in India and developing countries Immunodiagnosis has important role in screening, diagnosis and management of tuberculosis. SEVA TB ES-31 antigen has shown potential in detecting tuberculous IgG antibody in earlier studies from our laboratory. In the present study we have analysedSEVA TB ES-31 antigen specific immunoglobulinsIgM, IgA and IgG in clinically and bacteriologically confirmed pulmonary tuberculosis cases to determine the usefulness of specific immunoglobulin class in the diagnosis of patients attending the hospital. Of the 30 cases of pulmonary tuberculosis 25 (83.3%) were positive for IgG, 19 (63.3%) for IgM and 16 (53.3%) for IgA. On combining IgG and IgM positivity, sensitivity was increased to 93.3%. While combining IgG and IgA positivity, sensitivity increased to 90%. However specificity was decreased to 66.6% and 70% for both of these combinations respectively. It could be envisaged from this study that IgG antibody detection against ES-31 antigen showed acceptable sensitivity (83.3%) and specificity (86.6%) compared to IgM or IgA alone or in combination. When immune responses were analysed according to degree of sputum positivity, IgG response was observed to be predominant in all grades, compared to IgM or IgA antibody. The addition of IgM or IgA as an adjunct test increases the sensitivity but at the cost of specificity. Hence the detection of IgG alone is more useful compared to IgM or IgA assay, in detecting tuberculosis disease cases coming to the hospital.     

噬血的狂欢——试论现代小说中肺病意象的隐喻意义

疾病与文学发生联系古已有之,肺病更是文学作品中的一个常见意象。现代文学30年可以说是肺病意象的狂欢时代。在现代文学的特殊语境中,肺病作为一种特殊意象被赋予了与民族、社会、人性、女权等有关的隐含喻义。论文试图从鲁迅、丁玲、郁达夫三位作家的小说入手,对现代小说中的肺病意象进行一次现象的梳理和诗学的阐释。     

Proteomic analysis of the serum in patients with idiopathic pulmonary arterial hypertension

Idiopathic pulmonary arterial hypertension(IPAH) is a rare disease of unknown etiology.The exact pathogenesis of pulmonary arterial hypertension is still not well known.In the past decades,many protein molecules have been found to be in-volved in the development of IPAH.With proteomic techniques,profiling of human plasma proteome becomes more feasible in searching for disease-related markers.In present study,we showed the protein expression profiles of the serum of IPAH and healthy controls after depleting a few high-abundant proteins in serum.Thirteen spots had changed significantly in IPAH com-pared with healthy controls and were identified by LC-MS/MS.Alpha-1-antitrypsin and vitronectin were down-regulated in IPAH and may be valuable candidates for further explorations of their roles in the development of IPAH.     

肺内孤立性结节的HRCT扫描与病理相关研究

目的：探讨肺内孤立性结节（Solitary pulmonary nodule．SPN）的HRCT特征与良恶性病变之间的关系。方法：对66例肺内孤立性结节病灶进行螺旋HRCT增强扫描，观察结节增强的程度、周围的血管以及瘤肺界面的特征，来判定结节的良恶性。结果：病理证实50例周围型肺癌（Peripheral lung cancer，PLC）．16例良性结节。①PLC血供较良性结节丰富；②动脉期结节强化程度增强明显，平衡期达到峰值为PLC，PLC瘤肺界面清晰伴有深分叶，良性结节周围模糊。结论：PLC血供丰富、增强快，平衡期达最高，瘤肺界面清晰；良性结节增强慢，与肺界面关系模糊。     

本钢薄板坯连铸生产超深冲钢的试验研究

文章分析了本钢薄板坯连铸的设备和工艺特点,认为薄板坯连铸可以用来生产超深冲钢。而在工艺路线上,通过工业试验对比分析认为采用铁水预处理→复吹转炉→LF精炼→RH精炼→薄板坯连铸是最佳选择。     

Fresh air and good food: children and the anti‐tuberculosis campaign in the Netherlands c.1900–1940

As elsewhere in the Western world, between 1900 and 1940 the anti‐tuberculosis campaign in the Netherlands produced a wide range of initiatives to promote child health. In each of these the social and the medical were linked, as the hygienic ‘mood’ was encouraged by a child‐saving ethos that focused upon the poor. In this article the author discusses the choices that were made between anti‐tuberculosis interventions for children, the benefits projected on each of these and the categories of children for whom they were meant. Private and voluntary initiatives dominated the field, whereas the state turned out to be very reluctant to take responsibility. Medically controlled health camps for ‘weak’ children were a more important instrument than open‐air schools and mass medical examination. Medical surveillance produced new categories and data which in turn justified the continued growth of child hygiene after tuberculosis had become less of a threat during the 1930s.     

Detection of tubercular antibody and antigen in sera of bone and joint tuberculosis

Trichloroacetic acid (TCA) solubilized and DEAE fractionatedMycobacterium tuberculosis H₃₇Ra excretory-secretory (ES) antigen viz., Mtb EST DE1 and affinity purified goat antibodies to the TCA solubilized ES antigen (Mtb EST) were explored in detecting tubercular antibody and antigen respectively in sera of bone and joint tuberculosis by indirect and sandwich ELISA. Out of total 36 bone & joint tuberculosis cases, tubercular antibody was detected by indirect ELISA in 30 patients (sensitivity 83%), while circulating tubercular antigen was detected by sandwich ELISA in 27 patients (sensitivity 75%). Out of 34 non tubercular disease control cases, 10 patients showed positive reaction for antibody while only 4 patients showed positive reaction for antigen. In another group of 34 healthy subjects who were screened, 4 individuals showed positive reaction for tubercular antibody and 2 cases for antigen. This study shows that antigen detection assay using affinity purified anti Mtb EST antigen antibody is superior with overall specificity of 91% as compared to antibody detection assay with 75% specificity in bone & joint tuberculosis.