伏立康唑治疗侵袭性肺真菌病12例临床观察

应用伏立康唑治疗的12例侵袭性肺真菌病,观察疗效及不良反应。12例患者中有效8例,其中完全反应5例,部分反应3例。2例出现视力模糊,2例出现转氨酶升高,1例用药时出现轻微的头晕,后自行缓解。结果表明,伏立康唑是治疗侵袭性肺真菌病高效及安全药物。     

本钢薄板坯连铸生产超深冲钢的试验研究

文章分析了本钢薄板坯连铸的设备和工艺特点,认为薄板坯连铸可以用来生产超深冲钢。而在工艺路线上,通过工业试验对比分析认为采用铁水预处理→复吹转炉→LF精炼→RH精炼→薄板坯连铸是最佳选择。     

一种智能化NO输送系统的研制

为了满足临床吸入一氧化氮（NO）治疗安全与可靠的要求,研制一种和呼吸机同步的一氧化氮吸入装置是至关重要的．该装置使用气体流量计（GFM）检测呼吸机的吸气流量,通过气体稀释公式计算出在治疗条件下NO标气的流量,并由质量流量控制器（MFC）来控制NO标气送往呼吸回路,同时采用NO／NO2电化学传感器对进入人体前的治疗气中NO浓度和二氧化氮（NO2）浓度进行监测．试验结果表明：该一氧化氮吸入装置供N0标气相对于呼吸机供气滞后不到200ms,NO气体的用量相对于持续供气时节约了E／（I＋E）（吸呼比：I：E）、NO2的生成量〈2mg／L,从而不仅实现了监测与配气的智能化,而且也提高了NO治疗气精度、确保了治疗的可靠性与安全性．     

基于 3D FPN 的肺结节检测

肺癌早期发现与诊断对提高肺癌患者生存率至关重要。肺癌主要是由恶性肺结节造成的,通过肺结节早期检测与诊断能够及时发现病情,显著提高肺癌存活率。随着深度学习网络在医学辅助诊断领域应用的迅速发展,现已有很多深度网络被应用于肺结节检测。通过统计检测目标肺结节半径分布情况,发现大部分肺结节半径较小。因此,结合 CT 影像数据的三维特性,提出使用 3D FPN 进行单阶段肺结节检测,能够解决肺小结节检测效果不佳的问题。在公用肺结节数据集 LUNA16 上验证了网络的有效性,CPM 值达到 0.893 2,相比其它肺结节检测网络,检测效果提高了 2%。     

参芪扶正注射液对慢性肺心病患者血液流变学的影响

目的:观察参芪扶正注射液对慢性肺原性心脏病(以下简称肺心病)患者血液流变学的影响.方法:将74例慢性肺心病急性加重期患者随机分为A、B两组.A组(36例)在常规治疗的基础上加用参芪扶正注射液,B组(38例)仅给予常规治疗.两组均连续用药2周.治疗前后对血液流变学相关指标进行检测与对比观察.结果:患者经参芪注射液治疗后血液流变学示低切与高切变率下全血黏度、血浆比黏度、红细胞聚集指教、红细胞电泳时间、红细胞比积、血小板聚集率、纤维蛋白原均有显著性下降(P＜0.01或P＜0.05),与B组比较亦有显著下降(P＜0.05).临床总有效率及显效率A组分别为94.5%及50.0%;B组为73.6%及26.4%.A组疗效明显优于B组(P＜0.05),治疗期间未见参芪扶正注射液严重不良反应.结论:参芪扶正注射液能显著改善慢性肺心病急性加重期患者的血液流变性,是辅助治疗肺心病的一种有效、安全的药物.     

黛玉与香菱痨症的美学比较

《红楼梦》对黛玉、香菱的痨症作了较多的描述,两人所患之疾均是以吐血为主症的虚痨,病症为一,而病因实不相同。透过二人疾病发生的原因、治疗、预后等种种异同的现象,就会发现作者对这二个人物的安排是放在相对、相关的位置上来构思的。作者采用了疾病描写的手段,使人物关系更显得云遮雾断,扑朔迷离,从一个侧面充分体现了作品的伟大艺术成就。     

Fresh air and good food: children and the anti‐tuberculosis campaign in the Netherlands c.1900–1940

As elsewhere in the Western world, between 1900 and 1940 the anti‐tuberculosis campaign in the Netherlands produced a wide range of initiatives to promote child health. In each of these the social and the medical were linked, as the hygienic ‘mood’ was encouraged by a child‐saving ethos that focused upon the poor. In this article the author discusses the choices that were made between anti‐tuberculosis interventions for children, the benefits projected on each of these and the categories of children for whom they were meant. Private and voluntary initiatives dominated the field, whereas the state turned out to be very reluctant to take responsibility. Medically controlled health camps for ‘weak’ children were a more important instrument than open‐air schools and mass medical examination. Medical surveillance produced new categories and data which in turn justified the continued growth of child hygiene after tuberculosis had become less of a threat during the 1930s.     

Detection of tubercular antibody and antigen in sera of bone and joint tuberculosis

Trichloroacetic acid (TCA) solubilized and DEAE fractionatedMycobacterium tuberculosis H₃₇Ra excretory-secretory (ES) antigen viz., Mtb EST DE1 and affinity purified goat antibodies to the TCA solubilized ES antigen (Mtb EST) were explored in detecting tubercular antibody and antigen respectively in sera of bone and joint tuberculosis by indirect and sandwich ELISA. Out of total 36 bone & joint tuberculosis cases, tubercular antibody was detected by indirect ELISA in 30 patients (sensitivity 83%), while circulating tubercular antigen was detected by sandwich ELISA in 27 patients (sensitivity 75%). Out of 34 non tubercular disease control cases, 10 patients showed positive reaction for antibody while only 4 patients showed positive reaction for antigen. In another group of 34 healthy subjects who were screened, 4 individuals showed positive reaction for tubercular antibody and 2 cases for antigen. This study shows that antigen detection assay using affinity purified anti Mtb EST antigen antibody is superior with overall specificity of 91% as compared to antibody detection assay with 75% specificity in bone & joint tuberculosis.     

对学生体育参与意识的研究

本文采用问卷调查、文献资科、数理统计等方法，对安徽省马鞍山市14所学校学生参加课外体育活动现状进行抽样调查研究，分析出了学生参与体育意识的现状、特点及其影响因素，并针对如何增强体育参与意识，养成终生体育习惯提出建议．     

善用同理心,爱在细节处——以某起大学生疑似肺结核病的处理为例

应对公共卫生安全事件可能产生的严重后果进行分析,并在此基础上根据高校自身状况,针对学生情况制定出紧急处理,并在事后积极与学生沟通交流,避免矛盾,赢得家长的理解和支持。