药物分析教学改革的探讨

在2015版《中国药典》和新的药学专业教学大纲运用之际,本文对药物分析课程的理论和实验教学内容和方法进行了有益的探讨,希望通过对这门课的改革,在药物分析的层面上更好地培养理论基础扎实、实验动手能力强、善于思考的新时代的大学生,为国家培养更多合格的药学人才。     

基于案例教学的《制药工艺学》兴趣课堂的构建

目前高等教育课堂中普遍存在学生学习兴趣不高、课堂学习气氛不浓等现象,本文以案例作为载体,在激发学生学习兴趣的同时,促使学生自主学习,提高理论联系实际的能力,改善人才培养的质量,满足社会对人才的需求。     

药事管理学教学方法探讨

药事管理学是一门综合性学科,其知识涵盖面广,知识点繁多,涉及的法律法规多样,教学效果不佳。为了提高教学质量,让学生掌握相关知识点并熟练运用,该文对药事管理学的教学方法进行了改善与探索,包括项目教学法、PBL教学法、案例教学法、情境教学法、研讨教学法。上述方法能够提高学生自主学习的兴趣,为改善教学效果、提高课堂教学质量提供参考。     

高职“药物制剂技术”课程改革的思考

为提高"药物制剂技术"课程的教学效果,本课程组依托地方生物医药产学研联盟,从确立培养目标、选择教学内容、完成教学实施、强化操作技能等方面对该课程的教学改革提出思考并进行探索,通过教学改革,"药物制剂技术"课程的教学效果有了较大的改进。     

杭州市制药行业危险废物产污系数的研究

通过对杭州市辖区制药行业危险废物的调查统计，采用物料衡算和经验估算法，计算得到杭州市辖区原料合成类药物危险废物产污系数和杭州市辖区中间体加工类药物危险废物产污系数。研究涵盖了来自25家药厂的8种典型原料合成类药物和48种典型中间体加工类药物的危险废物产污系数及各药相关的生产工艺、生产规模和设备年限。反映出制药行业危险废物主要产生环节和工艺，为环境管理部门捉供宏观统计系数，同时开拓危险废物的控制和管理思路，为国家实行的危险废物处置收费制度提供理论参考。     

医药企业与学研机构合作研发创新药物的演化博弈研究

创新是我国从“医药大国”向“医药强国”转变的必由之路,由于我国医药企业创新能力不足等多种原因,阻碍了我国创新药物的发展,而医药企业与学研机构进行合作对促进创新药物的发展是十分必要的。本文建立了医药企业与学研机构的演化博弈模型,分析了政府参与下双方策略选择的动态演化过程以及策略选择的影响因素。基于以上基础,本文提出加大政府的财政支持、完善专利保护制度、搭建医药企业与学研机构的合作平台、完善有关合作创新的法律法规体系等建议。     

Marketing/R&D integration in the pharmaceutical industry

Integrating marketing and R&D inputs is one of the fundamental challenges in managing innovation. In the pharmaceutical industry, considering its reputed ‘technology push’ model of innovation, the challenge of integrating marketing and R&D could hardly be greater. Thus, the recent trend among pharmaceutical firms of implementing Marketing/R&D integrating mechanisms calls for upgrading our conceptualization of the innovation process in this industry. It also raises important questions regarding Marketing's contribution in new product development, and how to organize to assure that contribution is leveraged. We use the case of a pharmaceutical firm which recently implemented Marketing/R&D integrating mechanisms to examine Marketing's new roles. We find that the extreme conditions surrounding innovation in the pharmaceutical industry, notably the need to cope with Knightean uncertainty, highlight important contributions of Marketing input in R&D that deserve more attention. We suggest that Marketing's most important contribution under these conditions lies in ‘not getting it wrong’ rather than ‘getting it right,’ in setting minimum criteria in project evaluations rather than definite targets, and in refocusing the attention of R&D staff through the very process of providing this input. Given the value of these contributions, modern pharmaceutical firms would indeed be ill advised to think of drug discovery as merely a linear process. Drug development has become an interactive process where the timing, type and impact of Marketing involvement is balanced and managed via certain organizational mechanisms throughout the R&D process, which is an iterative one.     

Inter-firm R&D partnering in pharmaceutical biotechnology since 1975: Trends, patterns, and networks

This paper analyses a large, longitudinal database on inter-firm R&D partnerships formed in the high-tech pharmaceutical biotechnology industry since 1975. Our research indicates an overall growth in the number of annually, newly established R&D partnerships where research partners consistently prefer contractual partnerships to equity-based alliances. In the networks that develop through these R&D partnerships, small, entrepreneurial biotechnological companies take a leading role during the 1980s when biotechnology first became relevant for the pharmaceutical industry. The 1990s, however, show a different pattern with established, large pharmaceutical companies becoming more dominant, acting as nodal players with multiple partnerships with a variety of other companies.     

药用高分子材料学综合、设计性实验项目的探索与实践

药用高分子材料学是制药工程专业的一门基础课程,其理论教学枯燥乏味、抽象不易理解,这里探索了一种与理论教学紧密结合的综合、设计性实验教学项目,旨在提高学生学习兴趣的同时,加强学生对理论知识的认知和理解,培养学生的实践能力和创新精神。     

Scientific foundation, organization structure, and performance of biotechnology and pharmaceutical firms

Technologists seek to advance practical applications of science while scientists seek to advance knowledge which may or may not have a practical application. Firms with a stronger basic science focus, e.g. biology and chemistry, seek to advance their scientific knowledge foundation in addition to developing and selling innovative products. Firms with a more highly applied science foundation (medicine, engineering, etc.) prioritize the development and sale of innovative products. Combining an Absorptive Capacity (AC) approach with Transaction Cost Economics (TCE) this study explores and explains how firms gain knowledge and perform given their scientific focus.Findings indicate that firms with a stronger basic science orientation are less profitable than firms with a stronger applied science orientation. Applied science firms had more acquisitions and cooperative organizations but both types of firms were more likely to acquire other firms in their quest to build knowledge stores rather than partner. Partnerships with universities were more prevalent among basic science firms than with applied science firms.