我国STEAM教育改革的阻力与消解

加快推进我国STEAM教育改革不仅是培养综合型、创新型、应用型人才的必由之路,也是提升国家竞争力和教育发展应对自身危机的可行之径。然而,改革中却存在诸多阻力。从“教育改革”的视角出发探赜改革蕴含的阻力因素,并提出阻力消解对策对促进我国STEAM教育顺利开展、探索一条具有中国特色的STEAM教育发展道路具有重要价值。研究发现,我国STEAM教育改革在实践中遭遇了价值阻力、制度阻力、实际阻力和自身阻力。为消解阻力,应坚持STEAM教育价值先行的基本理路,推进不同主体的自我变革;加强制度供给,理顺STEAM教育与现行制度之间的关系;加大STEAM教师队伍建设力度,推进STEAM课程改革;促进STEAM教育的本体回归,破解“跨学科悖论”。     

阳光与阴影中的生存与反抗——论阿尔贝·加缪《鼠疫》的象征

解读了《鼠疫》中的象征,凸现了加缪作品"荒谬"和"反抗"的主题,颂扬了人们对瘟疫和战争的顽强反抗,体现了作者对人类生存状况和生命价值的深切关注及人道主义精神。指出在战争依然存在、瘟疫死灰复燃的今天,《鼠疫》仍具有重要的警世作用。     

无穷电阻网格任意两节点之间的等效电阻

利用二维傅里叶变换,求解了平面正方形无穷电阻网络任意两个不相邻节点之间的等效电阻的解析解,并推广引伸,用于其它类型的无穷电阻网络．     

大麦抗赤霉病性的遗传研究

采用特矮大麦／早熟３号、特矮大麦／紫皮大麦、特矮大麦９１－６４１１、９１－６４１１／早熟３号４具杂交组合的Ｐ１、Ｐ２、Ｆ１、Ｆ２、Ｂ１、Ｂ２世代，研究了大麦抗赤霉病性的遗传，结果表明，大麦抗郝霉病性表现 部分显性或超显性，细胞质作用不明显，在特矮大麦／早熟３号、特矮大麦／紫大麦和特矮大麦／９１－６４１１中，共同亲本特矮大感病性主要受一对隐性基因控制；在９１－６４１１／早熟３号中，抗赤霉病性为数量性     

乳腺癌耐受蛋白介导5-氟脲嘧啶的耐受及机制探讨

AIM To filtrate breast cancer resistance protein(BCRP)-mediated resistance agents and investigate the mechanism,so as to provide valuable datum for optimization clinical chemotherapy scheme to tumor with evaluation marker of BCRP expression. METHODS MTT assay was used to filtrate BCRP-mediated resistance agents with PA317/Tet-on/TRE-BCRP cell of different expression levels of BCRP after treated with different concentration anticancer agents. High performance liquid chromatography(HPLC) was applied to measure relative dose of intracellular retention resistance agents. Nuclear DNA fluorescence dye,Hochest 33258, staining and flow cytometry were adopted to detect apoptotic cells after treated with drugs. RESULTS There were shown increasing durg-resistance to 5-fluorouracil,methotrexate, doxirubicin, pirarubicin,etoposide and mitoxantrone followed with increasing expression of BCRP on PA317/Tet-on/TRE-BCRP cells(P＜0.05, n=3),but shown sensitive to paclitaxel, cisplatin, vincristine, mitomycin and vindesine. There also was shown significant negative correlation between the intracellular retention dose of 5-fluorouracil with different expression of BCRP(r=-0.885, P＜0.05, n=3).There were shown parallel results of that decreasing cellular apoptotic rate with increasing cellular expression of BCRP after treated with 5-fluorouracil by fluorescence dye staining and flow cytometry(P＜0.05, n=3),and also shown significate rise of the apoptotic rate of BCRP expression cells after treated with Ko143 (P＜0.05, n=3). Every group of cells could be different extently blocked in phase of G0/G1 treated with 5-fluorouracil. CONCLUSION Resistance of 5-fluorouracil could be especially mediated by conjugated with BCRP and acted as drug exclude-pump substrate. Cellular ability resistant to 5-fluorouracil-induced apoptosis could be reinforced by BCRP expression.     

日本枪刺下的井陉煤矿

井陉煤矿是河北省重要煤矿之一，在抗战时期，被日军侵占了8年之久。日本侵占井陉煤矿后，掠夺煤炭资源，奴役煤矿工人。面对日本的侵略行为，井陉军民进行了顽强的抵抗。     

Effect of deposition parameters on mechanical properties of TiN films coated on 2A12 aluminum alloys by arc ion plating (AIP)

1 Introduction Weight saving materials such as aluminum and its alloys are becoming increasingly important and have been attracting increasing attention over the past decade, specially in the automotive, aerospace and chemical industries, and electrical devices because of their high strength-to-weight ratio, high electrical and thermal conductivities, processability and recyclability and good resistance to degradation in some corrosive environments [1,2]. In the automotive industry, there is d…     

关于军用飞机着陆灯专用电源设计方案的定量计算

10 0 0 W军用飞机着陆灯的灯丝是一种非线性时变电阻 ,冷电阻极小 ( 0 .0 4Ω左右 ) ,工作几秒钟后才能达到额定阻值 ( 0 .9Ω ) ,在对该灯进行老炼及检测时 ,如何仿真飞机着陆时迅速点亮的实际情况 ,是设计这种专用电源的一大难题。本文运用非线性时变电阻理论和金陵职业大学电源专利技术 ,进行了分析和定量计算 ,成功地解决了这一难题     

人与自然的三次对话——浅论诗人生命体验的跋涉历程

人与自然的关系是文学创作的永恒母题。在人与自然的对称关系中,既有崇敬中的惶惶情愫,也有企图征服的大胆渴望,更有在平衡心境中的超越、契合。西方叙事文学用两千年记录下的人与自然的三次对话,浓缩了西方抒情诗人近二百年间的生命体验。这其中包括:一、自然崇拜情结;二、人与自然的对抗融合;三、人与自然的和谐统一;四、中西诗歌的共同指归。     

变压器套管检修与维护

通过对变压器套管发生故障的原因的分析，制定出减少套管故障的相应措施，从而获得变压器套管最佳的检修维护方式和处理此类故障的正确方法，对电力系统的稳定运行有较大的实用价值。