教育投入对经济增长的影响恒久不变吗--改革开放以来的路径演化分析

本文基于改革开放以来我国国家财政预算内教育经费以及 GDP 年度数据,运用非线性 MS (M)-VAR(p)模型,对我国教育投入与宏观经济增长之间的内在联动机制进行测度。结果表明：(1)教育投入增长率在较低水平时波动性较小、持续性较大,在较高水平时波动性较大、持续性较小。(2)宏观经济处于“低速”或“快速增长”态势时波动性较大,持续性较小;处于“中速增长”阶段时,波动性较小、持续性较大。(3)前期的 GDP 增长率对当期的教育投入增长率具有正向影响,前期的教育投入增长率对当期的GDP 增长率具有负向影响。(4)“教育与经济”系统处于“低速”或“中速增长区制”时,可能性更大、持续性更强,教育投入增长率与GDP增长率之间负相关;处于“快速增长区制”时,可能性最小、持续性最弱,教育投入增长率与GDP增长率之间正相关。     

固相萃取-UPLC—MS／MS测定食品中的黄曲霉毒素M1和B1

建立固相萃取与UPLC—MS／MS检测食品中黄曲霉毒素M1和黄曲霉毒素B1的方法。样品经乙腈提取和SPE小柱萃取净化,提取液经氮气吹干后,用50％甲醇水溶液定容。超高效液相色谱一串联质谱（UPLC—MS／MS）测定,采用电喷雾正离子（ESI＋）模式电离,多反应监测（MRM）模式检测。流动相为0．1％甲酸水溶液和甲醇,流速0．4ml／min,使用ZORBAX Eclipse XDB—C18色谱柱（100mm×3．0mm×1．8μm）为分析柱。黄曲霉毒素AFM1在0．1～50μg／kg范围内线性关系良好、黄曲霉毒素AFB1在0．1～10ug／kg范围内线性关系良好,相关系数均大于0．999;回收率在83．75％～97．8％之间;检出限AFMl为0．05μg／kg、AFBl0．02μg／kg。该法具有分析速度快,检测准确、灵敏度和回收率高等优点,适合食品中黄曲霉毒素M1、B1含量的检测。     

关于IMS中基于SIP协议的应用分析

IMS(IP Multimedia Subsystem)是IP多媒体子系统,是一种全新的多媒体3G业务形式,它能够满足现在的终端客户更新颖、更多样化多媒体业务的需求。目前,IMS被认为是下一代网络的核心技术,也是解决移动与固网融合的重要方式。它用基于SIP信令的IP网络对多媒体传输业务实现了可靠多元的控制。SIP(Session Initiation Protocol)是一项类似于HTTP的基于文本的C/S模式点对点通信协议,用于建立、修改和终止IP多媒体对话,为电信运营商及其合作伙伴和用户提供了新一代基于IP的服务。     

茼蒿挥发性成分的分析

采用同时蒸馏-萃取的方法，对辽宁鞍山、铁岭、抚顺、阜新产的茼蒿的挥发性成分进行了提取，采用GC／MS方法对挥发油进行了鉴定，并对四产地的挥发油化学成分进行了比较．     

从主体间性理论看庞德译汉诗的独特审美价值

在二十世纪诗歌发展史上,庞德所译汉诗有过不可忽视的影响。本文从不同侧面分析了这些译诗内各诗歌主体间的互动、东西文化元素的并存与交织、以及由庞译 引发的东西方诗学思想的融汇,指出庞译尽管瑕瑜互现,但体现了东西方诗歌与文化的主体间性关系,因而具备独特的审美价值。     

基于SPOC的师生双主体TPD教学模式探索和应用--以大学“高级日语”课程为例

在当今信息化时代,线上线下教育深度融合将成为必然。该文对标JF日语教育标准的评价体系中学生“接受”(理解)、“产出”(表达)、“相互行为”三种学习活动,探索基于SPOC的师生双主体TPD教学模式,并通过大学“高级日语”课程的线上线下教学实践和学生问卷调查结果,探讨了该教学模式的实施方法、内容、效果及存在的问题。     

Evaluation of the hepatoprotective and antioxidant activities of Rubus parvifolius L

The hepatoprotective and antioxidant activities of the n-butanol extract of Rubus parvifolius L. (RPL), a widely used medicinal plant, were evaluated. Results demonstrated that RPL extract possessed pronounced hepatoprotective effects against carbon tetrachloride (CCl₄)-induced hepatic injury in mice, which was at least partially attributed to its strong antioxidant capacity. Treatment with RPL extract markedly attenuated the increases in serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels caused by CCl₄ intoxication. It also significantly prevented the decrease in superoxide dismutase (SOD) activity and the increase in malondialdehyde (MDA) content of liver tissue. Meanwhile, histopathological changes of hepatic damage were also remarkably ameliorated. Phytochemical analysis based on high-performance liquid chromatography/tandem mass spectrometry (HPLC-MS/MS) revealed the presence of various phenolic compounds, including caffeic acid conjugates, ellagic acid glycosides, and flavonol glycosides, which might be responsible for the hepatoprotective and antioxidant activities of RPL.     

Method Development and Validation of Liquid Chromatography-Tandem Mass Spectrometry for Angiotensin-II in Human Plasma: Application to Study Interaction Between Atorvastatin & Olmesartan Drug Combination

Simple and sensitive Liquid Chromatography-Tandem Mass Spectrometry (LCMS/MS) method was developed and validated, then was implicated on hypertensive human subjects to study drug interaction of atorvastatin (ATVS) and Olmesartan (OLM) on status of Angiotensin-II (ANG-II). The ANG-II in plasma was extracted with 5 mL methanol containing 5 % formic acid through C₁₈ (cartridges) liquid–liquid extraction, dried and reconstituted with 1 mL of 16 % acetonitrile in 0.1 % formic acid in water. The chromatographic separation of ANG-II with a Agilent technology 6410 Triple quadrupole was carried multiple reaction monitoring scan mode with a Agilent 1290 Infinity LC system for UHPLC. The sample were separated on a (Thermo Scientific) Hy-Purity advance (50 × 4.6 mm, 5 μm) using Mobile Phase A: 16 % acetonitrile in 0.1 % formic acid in water and Mobile Phase B: 0.1 % formic acid in methanol at a flow rate of 0.3 mL/min, performed at ambient temperature. The mobile phase gradient of 16 % acetonitrile in water was linearly increased to 38 % acetonitrile over 10 min and subsequently the mobile-phase was increased to 100 % acetonitrile over 15 min. The developed method was validated for specificity, accuracy, precision, stability, linearity, sensitivity and recovery. The method was linear between peak area ratio of standard and internal standard over the range of 50–800 ng/mL. The method was successfully applied for the drug interaction study revealed levels of ANG-II were significantly higher in ATVS + OLM treatment condition as compared to individual treatment of OLM. This reflects the reason of low effectiveness of ATVS + OLM in combination instead of synergistic activity.

Electronic supplementary material

The online version of this article (doi:10.1007/s12291-014-0457-x) contains supplementary material, which is available to authorized users.