Stimation of reference interval of lipid profile in Assamese population

12hrs fasting samples of 1485 apparently healthy, Assamese population in the age group of 20–80 yrs., mostly from the urban area of Assam were tested for serum lipid profile that includes total cholesterol, triacylglycerol, high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C) and very low density lipoprotein cholesterol (VLDL-C) over a period of three years. The values (median and range in mg/dl) obtained were 170 (93–263); 110 (40–256); 40 (23–73); 103 (40–173) and 22 (8–51) respectively. After grouping these subjects according to the age and sex no significant difference were observed between most of the groups. Median and upper range of total cholesterol, HDL-C and LDL-C were found to be higher in women than in men in all the age groups. But triacylglycerol and VLDL-C concentrations were observed to be higher in the men than women except in age group of 61–70 yrs. It can be suggested that lipid values obtained in this study can be used as the reference value, based on which clinical correlation can be made.     

一类分形插值曲面的截线及其维数

对一类分形插值曲面和它的截线进行探讨．根据生成分形插值曲面的迭代函数系,导出了其截线的迭代函数系,证明了它的不变集（即分形插值曲面的截线）是具有间断点的分形插值函数的图像,并通过计算得到分形插值曲面的盒维数与其截线的盒维数之间的关系．     

Interference of anti-T4 autoantibodies in the single step free T4 radioimmunoassays

The thyroid hormone profile of a hypothyroid patient, with moderate sized diffuse goiter and history of exogenous thyroid hormone therapy, was found to be highly ambiguous. The total as well as free T4 levels were consistently high (out of range) with suppressed T3 (total and free) and elevated thyrotropin levels. We incubated the serum with the radio-iodine labelled T4 and observed that the patient’s serum bound about 50.5% of the total radioactivity resulting in 85.3% interference in the radioimmunoassay. On resolving the serum proteins by cellulose acetate electrophoresis, the radioactivity was detected in the gamma globulin band. The protein profile showed mildly raised levels of IgG. Therefore it was established that the patient’s serum carried T4 reactive antibodies (IgG) which were interfering in the immunoassays. Elevated anti-thyroid microsomal antibodies were also present in the patient’s serum. The anti-T4 antibodies were highly specific for T4 and did not show any cross reactivity with the T3 or its analogues used in the estimation of free T3. We stripped the serum by precipitating the immunoglobulins and were successful in estimating the levels of free T4 in the stripped serum by single step radioimmunoassy.     

‘Inclusion in Practice’: Programme Practices in Mainstream Preschool Classrooms and Associations with Context and Teacher Characteristics

This study observed the extent to which teachers supported the inclusion of children with disabilities into mainstream classrooms and involved monitoring 52 mainstream preschool settings in Greece. The association between programme quality, context and teacher characteristics was also tested. Findings showed that the quality of inclusion ranged from ‘low’ to ‘minimal’, with teachers more frequently implementing practices that only partially promoted participation for children with disabilities in academic and social classroom activities. The analysis also revealed that the quality of programming was not influenced by the model of special education provision, the group size, the number of children with disabilities, the training teachers had in special education or their teaching experience. The results are discussed both at a national and international level, revealing areas that need further examination into preschool inclusion quality.     

Thyroidal regulation of substrate kinetics properties of cytochrome oxidase in rat liver mitochondria

Effects of thyroidectomy (T_x) and subsequent treatment with 3,5,3’-triiodothyronine (T₃), and combined treatment (T_R) with T₃ + thyroxine (T₄) on substrate kinetics properties of cytochrome oxidase of rat liver mitochondria were examined. T_x resulted in lowering of cytochromes content with decrease in the enzyme activity, and K_m and V_max. T₃ and T_R regimens restored the cytochromes contents and the V_max values to normal. In control, T₃ and T_R groups the enzyme activity resolved in two kinetic components; in T_x group three kinetic components were evident. The K_m values for all components decreased significantly in the experimental groups with concomitant increase in catalytic efficiency, K_cat/K_m. Significant alterations in the contents of total phospholipid and of cholesterol were noted while the changes in the phospholipids composition were only of restricted nature. Regression analysis revealed that total phospholipid, cholesterol and phosphatidylcholine, phosphatidylethanolamine play significant role in fine tuning the enzyme activity.     

Impact of nodular size on the predictive values of gray-scale, color-Doppler ultrasound, and sonoelastography for assessment of thyroid nodules

Objective:To define the roles of gray-scale,color-Doppler ultrasound,and sonoelastography for the assessment of thyroid nodule to determine whether nodule size affects the differential diagnosis of ben...     

宁南山区外科治疗甲状腺疾病227例疗效分析

用统计学方法对宁夏回族自治区固原市医院227例甲状腺手术病人进行分析,探讨甲状腺疾病手术治疗的效果.甲状腺疾病的手术治疗有增多趋势,其疾病谱也有明显的变化,应引起广大医务工作者的关注.     

文化记忆资源的知识融通:从异构资源元数据应用纲要到一体化本体设计

[目的/意义]探索美术馆、图书馆、档案馆、博物馆等机构(GLAM)中多源异构文化记忆资源跨领域跨机构的知识融通解决方法和路径。[研究设计/方法]在“元数据应用纲要”的基础上,提出了“本体应用纲要”的概念,以上海图书馆手稿档案元数据应用纲要扩展为本体应用纲要为例,阐述了本体应用纲要设计的原则、方法和流程;以历史人文“数据基础设施”进一步构建了一体化本体及其知识融通模型,并验证基于本体应用纲要在一体化本体框架下的扩展以实现跨领域知识融通的方法。[结论/发现]元数据应用纲要为文化记忆资源的知识融通提供了结构化数据储备,本体应用纲要兼顾了特定资源类型的个性化需求,一体化本体的知识融通模型则用于保证知识建模的统一性和知识表示的一致性。[创新/价值]基于多种本体应用纲要的一体化本体设计方法和关联数据与知识图谱技术结合后,作为一种新的知识组织方法,为跨机构跨领域的知识融通提供了方法和路径。