Some oxidative stress related parameters in patients with head and neck carcinoma

Forty cases of head and neck cancer were studied for plasma superoxide dismutase, malondialdehyde and thiol levels and results were compared with a group of forty normal healthy volunteers. Mean plasma superoxide dismutase activity was not found to be altered while malondialdehyde concentration was significantly higher when compared with the control group. On the other hand, mean thiol level was significantly lowered. The data suggests increased level of oxidative stress in patients with head and neck cancer.     

低位直肠癌保肛根治术的体会（附112例报道）

目的探讨低位直肠癌患者行保肛根治术的临床应用。方法对我院收治的112例低位直肠癌患者进行保肛手术并观察术后效果。结果3例术后1周内发生吻合口瘘,二次手术造瘘1例,2例保守痊愈;5例发生术后肠梗阻,4例保守治疗痊愈,1例开腹二次手术后死亡;吻合口早期狭窄8例,术后14天扩肛痊愈。结论严格掌握保肛手术指征、合理选择患者、规范手术是低位直肠癌保肛根治手术成功的关键。     

印度谷螟幼虫肠道微生物降解聚乙烯的实验研究

按照ASTM标准方法以聚乙烯为唯一碳源培养螟蛾幼虫肠道微生物,扫面电镜（SEM）观察发现本实验菌种（T3菌）从表层开始侵蚀聚乙烯,而同一侵蚀区域其侵蚀程度也有差异,存在有明显的分层现象,故本菌种对聚乙烯的侵蚀为表面侵蚀。按照ASTM标准方法对实验后样品进行的拉伸性能测试表明,经T3菌处理的聚乙烯薄膜,随着培养时间的增加,拉伸强度与断裂伸长率均无明显规律,总体上拉伸强度与断裂伸长率均比原样要大,与理论推测的结果不符。     

淋巴液对肠系膜上动脉闭塞性休克的影响

为探讨肠淋巴液对肠系膜上动脉闭塞性休克(SMAO休克)的影响,对SMAO休克大鼠给予肠淋巴液或血浆治疗,并以生理盐水作对照,观察其对血压及存活率的影响。结果表明,开夹后90min起,肠淋巴液治疗组的血压显著高于对照组(P<0.05),其4h存活率也显著优于对照组(P<0.05),而血浆组与对照组血压和存活率未见统计学差异(P>0.05),提示肠淋巴液对SMAO休克具有提升血压及延长存活时间的作用。     

PCR-DGGE技术分析孤独症家庭成员肠道菌群结构

目的应用PCR-DGGE（denaturing gradient gel electrophoresis,变性梯度凝胶电泳）技术对孤独症家庭成员肠道微生物菌群结构进行研究.材料和方法提取粪便细菌总基因组DNA,PCR扩增细菌16S rDNA基因V3可变区,DGGE方法检测PCR产物.结果建立了孤独症家庭成员肠道菌群组成的DGGE指纹图谱,分析结果显示孤独症儿童肠道菌群结构的相似度为0.42-0.65,家庭内孤独症儿童与父母之间的相似度为0.42-0.68.结论 PCR-DGGE技术是一种快速有效的用于分析研究人体肠道菌群结构的技术.孤独症儿童肠道菌群结构与父母的相似度较高,提示生活环境对肠道菌群的组成有影响.     

中下段食管癌三野与四野三维适形照射的比较

目的:比较中下段食管癌三维适形放射治疗常见的三野照射与四野照射方法的临床物理参数,优化放疗治疗计划。方法:随机选取中下段食管癌患者,采用VARIAN公司Eclipse治疗计划系统。按照ICRU50号报告指导原则勾画靶区,并分别设计三野与四野三维适形治疗计划,PTV所有方向上均放相同的边界5mm。然后利用体积剂量直方图DVH对两种布野方式的治疗计划靶区量分布,危及器官保护等参数进行分析和比较。处方剂量50Gy/25F。结果:两种照射方式靶区剂量分布情况相似,脊髓受照射剂量三野优于四野。在肺V20以及V5指标中,四野照射明显优于三野照射,在肺V30指标上无明显差异。结论:中下段食管癌三维适形放疗中,四野照射在肺V20、V5指标上优于三野照射计划,从预防严重放射性肺损伤角度上具有优势。     

介入治疗联合放射治疗对原发性肝癌的治疗效果研究

回顾分析60例因晚期肝癌不能行手术切除的肝癌患者的临床资料,对介入手术联合放射治疗前后原发生肝癌的癌栓大小的变化进行比较,发现21例癌栓完全消失,13例癌栓缩小,24例无变化,2例进展,癌栓消失和缩小占55.67%,所以介入治疗联合放射治疗对原发性肝癌的治疗的有效的、可行的、安全的.     

胃癌细胞SGC7901体外生长条件的优化研究

以胃癌细胞SGC7901为研究对象,用流式细胞仪和细胞总DNA分析技术讨论了不同培养基和不同保存条件对胃癌细胞体外生长的影响。     

Gastric carcinoma with osteoclast-like giant cells: a case report and review of the literature

Gastric carcinoma with osteoclast-like giant cells (OGCs) is an extremely rare tumor. So far, only six cases have been reported in the literature. Here we report an additional case of this tumor in a Chinese 78-year-old man presented with abdominal pain, vomiting, and hematemesis. Physical examination and gastroscopy revealed a tumor in the gastric antrum. The biopsy and pathological findings indicated a gastric adenocarcinoma with OGCs, which were present in both the tumor and the metastatic lymph nodes. Further immunohistochemical staining indicated that OGCs were reactive with CD68, CD45, and vimentin protein, but not with pancytokeratin, carcinoembryonic antigen, or epithelial membrane antigen, suggesting the monocytic/histiocytic derivation of these OGCs. In situ hybridization for Epstein-Barr virus showed no nuclear positivity in either adenoearcinoma or OGCs. Postoperative follow-up showed that the patient had survived for at least 6 months without recurrence. Further investiga-tion is warranted to clearly define the prognostic significance of OGCs in gastric carcinoma.     

Subglottic adenoid cystic carcinoma mistaken for asthma

of the tumor. The diagnosis of subglottic adenoid cystic carcinoma should be considered in patients who are characterized by dyspnea, cough, and stridor, but do not respond to regular anti-asthmatic therapy.