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排序方式: 共有66条查询结果,搜索用时 31 毫秒
51.
分析了HSPs(热休克蛋白)的功能与特性、运动引起HSPs表达的生物学功能以及HSPs表达后对酶、免疫、抗氧化、分子伴侣的作用和对凋亡的影响,从中总结HSPs对运动训练的意义。 相似文献
52.
Jyotsna A. Patil Arun J. Patil Ajit V. Sontakke Sanjay P. Govindwar 《Indian journal of clinical biochemistry : IJCB》2012,27(2):134-140
The aim of this study was to see the biochemical effects of pesticides on sprayers of grape gardens before and after 15 days of vitamin E supplementations in Western Maharashtra (India), who were occupationally exposed to various pesticides over a long period of time (about 5 to 15 years). Blood samples were collected from all study group subjects for biochemical parameters assays before and after 15 days of vitamin E supplementation. Sprayers of grape gardens were given 400 mg of vitamin E tablet/day for 15 days. After 15 days of vitamin E supplementation to sprayers of grape gardens, we observed significantly decreased aspartate transaminase (10.88 %, P < 0.05, r = 0.88), alanine transaminase (25.92 %, P < 0.01, r = 0.46) and total proteins (3.32 %, P < 0.01, r = 0.33), whereas, no statistically significant change was found in serum acetyl cholinesterase, C-reactive proteins, albumin (ALB), globulins and ALB/globulin ratio as compared to before vitamin E supplementation. Sprayers of grape gardens, who received vitamin E supplementation, showed significantly decreased serum lipid peroxide (LP) (18.75 %, P < 0.001, r = 0.63) and significantly increased RBC-superoxide dismutase (SOD) (12.88 %, P < 0.001, r = 0.85), RBC-Catalase (CAT) (24.49 %, P < 0.001, r = 0.70), plasma ceruloplasmin (CP) (4.6 %, P < 0.01, r = 0.80), serum zinc (4.57 %, P < 0.01, r = 0.83) and serum copper (4.37 %, P < 0.01, r = 0.79) as compared to values before vitamin E supplementation. These results showed that vitamin E supplementation has ameliorating effects on these transaminase enzymes, suggesting that it may have a protective effect on liver, from pesticides induced damage. In this study vitamin E supplementation might have decreased LP levels by breaking chain reaction of lipid peroxidation. Present results indicate that vitamin E plays a crucial role in restoring the antioxidant enzymes such as SOD, CAT and CP, in population exposed to pesticides. This helps to enhance its antioxidant ability. Therefore, it is suggested that farmers, pesticide applicators, workers in the pesticide industry and other pesticide users, who come in regular contact with pesticides, may be benefited by supplementation with vitamin E. 相似文献
53.
Salvador Llana-Belloch Jose Ignacio Priego Quesada Pedro Pérez-Soriano Ángel G. Lucas-Cuevas Andrea Salvador-Pascual Gloria Olaso-González 《European Journal of Sport Science》2016,16(5):609-617
Disinfection by-products (DBPs) are generated through the reaction of chlorine with organic and inorganic matter in indoor swimming pools. Different DBPs are present in indoor swimming pools. This study evaluated the effects of different chlorinated formations in oxidative stress and lung damage in 20 swimmers after 40?min of aerobic swimming in 3 indoor pools with different characteristics. Biological samples were collected to measure lung damage (serum-surfactant-associated proteins A and B), oxidative stress parameters (plasma protein carbonylation and malondialdehyde, and whole-blood glutathione oxidation), and swimming exertion values (blood lactate) before and after exercise. Free chlorine and combined chlorine in water, and chlorine in air samples were determined in all the swimming pools. Chlorination as disinfection treatment led to the formation of chloramines in water samples, mainly mono- and dichloramine. However, free chlorine was the predominate species in ultraviolet-treated swimming pool. Levels of total chlorine increased as a function of the swimming activity in chlorinated swimming pools. The lower quality of the installation resulted in a higher content of total chlorine, especially in air samples, and therefore a higher exposure of the swimmer to DBPs. However, the concentration level of chlorinated DBPs did not result in significant variation in serum-surfactant-associated proteins A and oxidative stress parameters in swimmers. In conclusion, the quality of the installation affected the DBPs concentration; however, it did not lead to lung epithelial damage and oxidative stress parameters in swimmers. 相似文献
54.
采用Trivelli等报道的Bio-Rex70阳离子交换树脂微柱层析法和Roger等报道的果糖胺法(两法均作了适当修改),分别对73例糖尿病患者及61例正常人进行了HbA_(1c)、HbA_1及糖基化血浆蛋白(Gpp)的测定.结果显示患者与正常人之间HbA_(1c)、HbA_1、Gpp均值有非常显著性差别.患者空腹血糖均值与HbA_(1c)、HbA_1、Gpp均值之间均有极显著的相关性.患者HbA_(1c)与HbA_1之间相关系数有极显著意义.证明HbA_(1c)、HbA_1与Gpp均可作为糖尿病控制较准确的客观指标.作者在提高微柱法分离度的关键问题上作了改进,找出了恰当的洗脱液Ⅰ与Ⅱ的Na~+浓度,分别为0.020mol/L与0.070mol/L.分离HbA_(1a+b)与HbA_(1c)结果尚称满意,柱间CV分别为3.1%与2.2%.在降低洗脱液Ⅰ、Ⅱ、Ⅲ中剧毒物质氰化钾的浓度问题上也作了研究,找出了较文献报道低2.5倍的氰化钾浓度,即由0.010mol/L降低到0.004mol/L.在果糖胺法中,采用5min与15min两次比色,用10%冰醋酸终止反应,提高了此法的精密度与重复性,批内CV为2.3%,批间CV为2.7%. 相似文献
55.
A. Ray S. L. Dayalu Naik A. K. Bahadur S. T. Pasha R. S. Rautela B. K. Sharma 《Indian journal of clinical biochemistry : IJCB》2001,16(1):101-105
Serum levels of various lipid parameters, i.e., triglycerides, total cholesterol, alpha lipoprotein or high density lipoprotein
(HDL)-cholesterol and beta lipoprotein or low density lipoprotein (LDL)-cholesterol were measured in a total of 138 histologically
proven cases of breast cancer along with 146 control women. The mean levels of serum triglycerides, total cholesterol and
LDL-cholesterol were found to be significantly higher in breast cancer cases as compared to controls. However, lower mean
levels of serum HDL-cholesterol and sex-hormone binding glubulin (SHBG) were observed in breast cancer patients than the control
subjects. The results indicate a probable relation between serum lipids and the activity of sex-hormones. Moreover, the study
reflects an overall disturbance of lipid metabolism in the pathological process of breast cancer. 相似文献
56.
点样位置对血清蛋白醋酸纤维薄膜电泳行为的改变 总被引:3,自引:0,他引:3
血清蛋白室温下进行醋酸纤维薄膜电泳时,点样线靠近阳极端则有蛋白朝阴极运动,低温下移动方向相同而速度变慢。兰色葡聚糖和溴酚兰在对应条件下电泳表明,主要是薄膜表面溶剂蒸发,造成缓冲液由两端朝中部补充而流动,从而改变了部分低荷质比血清蛋白的电泳行为。此异常现象证实缓冲液流动可改变蛋白质电泳行为,可用于验证电泳影响因素的设计性实验教学。 相似文献
57.
李文辉 《荆门职业技术学院学报》2000,15(6):83-88
随着高分辨核磁共振(NMR)仪和多维NMR技术的快速发展,近年来高场NMR仪已成为测定生物大分子在溶液中的三维结构的最强有力的手段。目前已有1700多个生物大分子的溶液结构用高分辨NMR技术进行了测定。该文简要综述了这一高新技术的特点、测定流程,并分析了若干实例。 相似文献
58.
The purpose of this study was to evaluate the relationship between the physicochemical properties of saliva such as flow rate,
pH, buffering capacity, calcium level, total protein and total antioxidant levels in caries free and caries active children.
The present study included one hundred and twenty healthy children who were divided into two groups; group I and group II
comprising of age groups 7–10 and 11–14 years, respectively. Both the groups were then sub-divided equally according to gender.
They were further divided into caries free and caries active with 15 children in each group. Unstimulated saliva was collected
by suction method and flow rates were determined. The samples were then analyzed for pH, buffering capacity, total protein,
calcium and total antioxidant capacity. The data was statistically analyzed using student t test (unpaired). The results revealed that when all these parameters were compared among the caries free and caries active
children, flow rate, pH, buffering capacity were slightly reduced in caries active children, but total protein and total antioxidant
capacity of saliva increased significantly in caries active children and the total calcium decreased significantly in caries
active children. Within the limitation of this study, we conclude that, the physicochemical properties of saliva play a major
role in the development of caries. 相似文献
59.
植物抗病因子是近年来生物学上的研究热点,本文较为详细地介绍了病原相关蛋白的发现、类型、性质、结构、生物学功能、分布以及在植物抗病中的作用,为深入进行这类蛋白的研究提供了参考。 相似文献
60.
Bcl-2蛋白家族根据其在细胞凋亡中的作用,分为抑凋亡蛋白和促凋亡蛋白.在骨骼肌细胞和心肌细胞内,Bcl-2家族成员之间形成二聚体,调节细胞是否进入凋亡程序.不同强度的运动对骨骼肌、心肌和淋巴细胞凋亡的影响不尽相同. 相似文献