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151.
恶性肿瘤(癌症)是尚未被攻克的重大疾病之一,主要原因之一是临床上抗肿瘤药物效用不大.具有抗肿瘤活性的阳离子肽(CAP)主要结合肿瘤细胞膜并破坏膜结构,这是通过肽的正电荷与肿瘤细胞膜的负电荷之静电吸引来实现的.与传统化疗药物相比,绕过肿瘤细胞的耐药机制是CAP最突出的优势.本文对抗肿瘤肽的主要结构特征、抗肿瘤效果和抗肿瘤机制(以鲎素为例)进行了综述.作者认为,寻找靶向肿瘤干细胞的CAP对于治愈肿瘤具有特别重要的意义.另外,通过化学改构和新剂型研制,CAP将具有高靶向性和低毒性,给抗肿瘤药物开发提供新的动力. 相似文献
152.
以江泽民为核心的党的第三代领导集体 ,根据中国政治经济建设不断发展的实际 ,勇于探索 ,在社会主义初级阶段理论、所有制理论以及经济发展战略等方面 ,创造性地运用和发展了邓小平理论 ,使邓小平理论不断深化、丰富和发展 相似文献
153.
行动德育强调构建以大学生为中心的家庭、学校、用人单位(企业)三位一体的德育工作运行模式。这一模式重在大学生的德育实践,把学校、家庭与用人单位紧密联系在一起,相互配合、相互支持,共同推动大学生道德力的提高,进而培养出符合社会需求的高技能人才。 相似文献
154.
Burcu Tezcan-Unal 《Educational Action Research》2018,26(4):641-654
Observing peers for professional development is a familiar and valuable practice but not always favoured in many educational institutions. This small-scale action research (AR) was conducted in an institution where teachers are accustomed to regular peer observation, requiring each teacher to conduct peer observation and to reflect in their teachers’ portfolios. Conventionally, to fulfil the requirement each teacher finds a colleague to observe them either with or mostly without a certain focus. This study, however, employed action research methodology to inquire into a collegial peer observation model to improve this organisational practice. It aimed to promote mutual growth of the participating faculty members in an agreed area. Including the author, five faculty members, who are midcareer and experienced English language teachers, acted as members of the consultation group. In the AR project, appreciative inquiry was used when reflecting on the observed classes and during focus group interviews. As a result of this AR, at least two levels of knowledge were generated: first-person (author) and second-person (the team). The knowledge claim that this practitioner research constructed is ‘When small groups of teachers conduct peer observations focusing on a common concern, learning and collegial growth may increase.’ It is expected to lead to a third-person stage in the department and the academic community in general. 相似文献
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156.
This paper explores and challenges the rationale for current, mainstream approaches to teachers’ continuing professional development (CPD) within schooling systems. Such approaches are significantly influenced by neoliberal and managerial pressures, evident in advocacy for generic, individualistic models of teacher learning, often focused on specific state-sanctioned domains. The paper draws upon a précis of recent action research literature, and empirical research from Sweden, to argue for an alternative paradigm, based on the practices and principles of participatory and collaborative action research. Action research is not presented as a simplistic ‘method’ which can be ‘applied’ regardless of context, but is explicitly focused on situated, specific, local sites. While more managerial and neoliberal practices can close down debates necessary for effecting real improvements in practice, evidence suggests action research, in its emancipatory iterations, enables a rich conception of educational practice which cannot be ‘managed’ into existence by a simplistic application of ‘what works.’ 相似文献
157.
158.
周小丹 《佳木斯教育学院学报》2012,(6):398-398
舞蹈是用人体的动作和姿态来反映社会生活表达思想感情的一种艺术形式。它和音乐、文学、美术和戏剧有着密切的联系,因此,它又是一种综合性的艺术。各种不同的艺术创作领域都有着自身艺术门类所独特的表现手段和表现方法,如文学通过文字表现,美术通过色彩表现,音乐通过音响表现,而舞蹈则是通过人体动作来表现的。本文将针对舞蹈创编中如何进行形象模仿。 相似文献
159.
行政抵抗权之法理分析 总被引:1,自引:0,他引:1
于桂凤 《十堰职业技术学院学报》2008,21(3):25-27
目前众多国内外的学者纷纷进行对相对人的抵抗权的研究,我们国家相关法律也对此做了一些类似规定。但是,我国行政法对于相对方的抵抗权的规定一直处于"犹抱琵琶半遮面"的状况,只在为数不多的法律文件中做了规定,因此作者认为行政相对方抵抗权已经能够在我国法律体制中发现,但是需要对其进行系统分析研究。 相似文献
160.
In our article, we explore the possibility of formulating theses about teaching as one way to use research as a basis for educational action. The theses are formulated from current educational research on teaching and learning in higher education. We also explore the potential for action and the consequences derived from the theses. With our theses, we criticise less complex ways of using research for educational purposes. Through theses we can suggest directions for action without prescribing certain methods or procedures and provide answers without reducing the teachers' possibilities for choice or diminishing their responsibility for their actions. Our exploration is an invitation to a collaborative exploration of theses on teaching and learning in order to broaden and deepen our shared basis for educational action. 相似文献