Effects of dietary antioxidants on training and performance in female runners

Abstract

Exercise-induced oxidative stress is implicated in muscle damage and fatigue which has led athletes to embark on antioxidant supplementation regimes to negate these effects. This study investigated the intake of vitamin C (VC) (1 g), blackcurrant (BC) juice (15 mg VC, 300 mg anthocyanins) and placebo in isocaloric drink form on training progression, incremental running test and 5-km time-trial performance. Twenty-three trained female runners (age, 31±8 y; mean±SD) completed three blocks of high-intensity training for 3 wks and 3 days, separated by a washout (~3.7 wks). Changes in training and performance with each treatment were analysed with a mixed linear model, adjusting for performance at the beginning of each training block. Markers of oxidative status included protein carbonyl, malondialdehyde (in plasma and in vitro erythrocytes), ascorbic acid, uric acid and erythrocyte enzyme activity of superoxide dismutase, catalase and glutathione peroxidase were analysed. There was a likely harmful effect on mean running speed during training when taking VC (1.3%; 90% confidence limits ±1.3%). Effects of the two treatments relative to placebo on mean performance in the incremental test and time trial were unclear, but runners faster by 1 SD of peak speed demonstrated a possible improvement on peak running speed with BC juice (1.9%; ±2.5%). Following VC, certain oxidative markers were elevated: catalase at rest (23%; ±21%), protein carbonyls at rest (27%; ±38%) and superoxide dismutase post-exercise (8.3%; ±9.3%). In conclusion, athletes should be cautioned about taking VC chronically, however, BC may improve performance in the elite.     

Caffeine supplementation does not affect match activities and fatigue resistance during match play in young football players

Abstract

The study examined the effect of caffeine supplementation on match activities and development of fatigue during a football match. In a randomised, double-blind cross-over design, two experimental football games separated by 7 days were organised between the junior teams of two professional football clubs (17.6 ± 1.1 years (±s), 71.7 ± 6.9 kg, 13.9% ± 5.0% body fat). The players ingested either a capsule of 6 mg · kg^?1 b.w. caffeine or placebo (dextrose) 65 min prior to the matches. Match activities were assessed using the ZXY match analysis system, and a Yo-Yo intermittent recovery test–level 2 (Yo-Yo IR2) was conducted immediately post-game. Heart rate was monitored throughout the game, and blood samples were obtained at baseline, half-time and after the game. There were no differences between caffeine and placebo regarding total distance covered (10,062 ± 916 vs 9854 ± 901 m), high-intensity running (557 ± 178 vs 642 ± 240 m), sprinting distance (109 ± 58 vs 112 ± 69 m) or acceleration counts (123 ± 31 vs 126 ± 24). In both trials, players displayed lower (P < 0.05) values in total distance and acceleration counts in the last 15 min compared to all other 15-min periods of the matches. Post-game Yo-Yo IR2 performance was not different between game trials (caffeine: 829 ± 322 m; placebo 819 ± 289 m). In conclusion, oral caffeine administration does not appear to have an ergogenic effect in young football players during match play.     

Effects of caffeine on time trial performance in sedentary men

Abstract

It is not known if ergogenic effects of caffeine ingestion in athletic groups occur in the sedentary. To investigate this, we used a counterbalanced, double-blind, crossover design to examine the effects of caffeine ingestion (6 mg · kg^?1 body-mass) on exercise performance, substrate utilisation and perceived exertion during 30 minutes of self-paced stationary cycling in sedentary men. Participants performed two trials, one week apart, after ingestion of either caffeine or placebo one hour before exercise. Participants were instructed to cycle as quickly as they could during each trial. External work (J · kg^?1) after caffeine ingestion was greater than after placebo (P = 0.001, effect size [ES] = 0.3). Further, heart rate, oxygen uptake and energy expenditure during exercise were greater after caffeine ingestion (P = 0.031, ES = 0.4; P = 0.009, ES = 0.3 and P = 0.018, ES = 0.3; respectively), whereas ratings of perceived exertion and respiratory exchange ratio values did not differ between trials (P = 0.877, ES = 0.1; P = 0.760, ES = 0.1; respectively). The ability to do more exercise after caffeine ingestion, without an accompanying increase in effort sensation, could motivate sedentary men to participate in exercise more often and so reduce adverse effects of inactivity on health.     

A new variable inspiratory muscle loading technology

Inspiratory muscle training (IMT) is becoming more popular in sporting populations as contentious issues associated with the magnitude of its effect as an ergogenic training aid are gradually dispelled. The authors believe that the efficacy of IMT can be further improved through development of the loading technologies. The basis for this belief is that current IMT stimuli do not simulate the demands placed upon the inspiratory muscles during exercise. We identify the design and initial trialling of a new, variable IMT technology, whereby the load throughout an inspiration can be adjusted to fit the dynamic pressure generating capacity of an individual. This should enable the exploration of high specificity in terms of inspiratory muscle loading as a possible means of further enhancing athletic performance. The new technology consists of a high-speed occlusion valve and control system that applies independent, sequential point loads to an inspiration. Manipulation of these point loads provides a fully variable loading profile. Twelve healthy adult male subjects participated in a feasibility study involving constant load, moderate intensity exercise in the presence of the load. The resulting data have been used to develop future recommendations for application and advancement of the technology.     

Effect of sulphurous mineral water in haematological and biochemical markers of muscle damage after an endurance exercise in well-trained athletes

Abstract

To investigate the effects of sulphurous mineral water (SMW) after a hydroponic treatment on muscle damage, antioxidant activity and peripheral blood changes induced by submaximal exercise. Thirty well-trained male triathletes were supplemented with SMW or placebo: 3 weeks of placebo, 30 days of wash out and 3 weeks of SMW. After both periods, participants ran for 2 h at 70% maximal aerobic speed. Antioxidant enzymes, lipid peroxidation, antioxidant capacity and blood cell markers were compared between placebo and SMW at pre-exercise (T₀), immediately post-exercise (T₁), 24 h post-exercise (T₂) and 48 h post-exercise (T₃). Total thiols decreased until T₃ vs. T₀ for both placebo and SMW; transient red blood cells, haemoglobin and haematocrit increased were shown at T₁ vs. T₀ and for leucocytes until T₂ vs. T₀, only for placebo group. Total thiols increased significantly in SMW vs. placebo at T₀; Thiobarbituric acid reactive species was significantly higher at T₀, T₁, T₂ and T₃; catalase increased significantly at T₁; creatine phosphokinase decreased significantly at T₁, T₂ and T₃, although no significant differences were found at T₀. Furthermore, red blood cells, haemoglobin and haematocrit were significantly higher and leucocytes were significantly lower at T₀ and T₁ in SMW group vs. placebo group. This study suggests that three weeks of SMW supplementation may protect from exercise-induced muscle damage.     

The effect of acute caffeine ingestion on upper and lower body anaerobic exercise performance

Abstract

The current study examined the effect of acute caffeine ingestion on mean and peak power production, fatigue index and rating of perceived exertion (RPE) during upper body and lower body Wingate anaerobic test (WANT) performance. Using a double-blind design, 22 males undertook one upper body and one lower body WANT, 60?min following ingestion of caffeine (5?mg*kg^?1) and one upper body and one lower body WANT following ingestion of placebo (5?mg*kg^?1 Dextrose). Peak power was significantly higher (P?=?.001) following caffeine ingestion in both upper and lower body WANT. Peak power and mean power was also significantly higher during lower body, compared to upper body WANTs irrespective of substance ingested. However, caffeine ingestion did not enhance mean power neither in upper nor lower-body WANT. There were no significant differences in mean fatigue index as a consequence of substance ingested or mode of exercise (all P?>?0.05). For RPE there was also a significant substance ingested X mode interaction (P?=?.001) where there were no differences in RPE between caffeine and placebo conditions in lower body WANTs but significantly lower RPE during upper body WANT in the presence of caffeine compared to placebo (P?=?.014). This is the first study to compare the effects of caffeine ingestion on upper and lower body 30-second WANT performance and suggests that caffeine ingestion in the dose of 5?mg*kg^?1 ingested 60?min prior to exercise significantly enhances peak power when data from upper and lower body WANTs are combined.     

The Governor has a sweet tooth – Mouth sensing of nutrients to enhance sports performance

Abstract

The oral–pharyngeal cavity and the gastrointestinal tract are richly endowed with receptors that respond to taste, temperature and to a wide range of specific nutrient and non-nutritive food components. Ingestion of carbohydrate-containing drinks has been shown to enhance endurance exercise performance, and these responses have been attributed to post-absorptive effects. It is increasingly recognised, though, that the response to ingested carbohydrate begins in the mouth via specific carbohydrate receptors and continues in the gut via the release of a range of hormones that influence substrate metabolism. Cold drinks can also enhance performance, especially in conditions of thermal stress, and part of the mechanism underlying this effect may be the response to cold fluids in the mouth. There is also some, albeit not entirely consistent, evidence for effects of caffeine, quinine, menthol and acetic acid on performance or other relevant effects. This review summarises current knowledge of responses to mouth sensing of temperature, carbohydrate and other food components, with the goal of assisting athletes to implement practical strategies that make best use of its effects. It also examines the evidence that oral intake of other nutrients or characteristics associated with food/fluid intake during exercise can enhance performance via communication between the mouth/gut and the brain.     

Oral conjugated linoleic acid supplementation enhanced glycogen resynthesis in exercised human skeletal muscle

Present study examined the effects of conjugated linoleic acid (CLA) supplementation on glycogen resynthesis in exercised human skeletal muscle. Twelve male participants completed a cross-over trial with CLA (3.8 g/day for 8 week) or placebo supplements by separation of 8 weeks. CLA is a mixture of trans-10 cis-12 and cis-9 trans-11 isomers (50:50). On experiment day, all participants performed 60-min cycling exercise at 75% VO₂ max, then consumed a carbohydrate meal immediately after exercise and recovered for 3 h. Biopsied muscle samples from vastus lateralis were obtained immediately (0 h) and 3 h following exercise. Simultaneously, blood and gaseous samples were collected for every 30 min during 3-h recovery. Results showed significantly increased muscle glycogen content with CLA after a single bout of exercise (P < 0.05). Muscle glucose transporter type 4 expression was significantly elevated immediately after exercise, and this elevation was continued until 3 h after exercise in CLA trial. However, P-Akt/Akt ratio was not significantly altered, while glucose tolerance was impaired with CLA. Gaseous exchange data showed no beneficial effect of CLA on fat oxidation, instead lower non-esterified fatty acid and glycerol levels were found at 0 h. Our findings conclude that CLA supplementation can enhance the glycogen resynthesis rate in exercised human skeletal muscle.     

Effect of creatine plus caffeine supplements on time to exhaustion during an incremental maximum exercise

Abstract

This study investigated the effects of acute caffeine ingestion following short-term creatine supplementation on an incremental cycling to exhaustion task. Twelve active males performed the task under three conditions: baseline condition (BASE, no ergogenic aid), creatine plus caffeine condition (CRE + CAF), and creatine with placebo condition (CRE + PLA). Following the establishment of BASE condition, participants were administered CRE + CAF (0.3 g·kg^?1·day^?1 of creatine for 5 days followed by 6 mg·kg^?1 of caffeine 1 h prior to testing) and CRE + PLA (0.3 g·kg^?1·day^?1 of creatine for 5 days followed by 6 mg·kg^?1 of placebo 1 h prior to testing) in a double-blind, randomized crossover and counterbalancing protocol. No significant differences were observed in relative maximal oxygen consumption ([Vdot]O_2max) (51.7±5.5, 52.8±4.9 and 51.3±5.6 ml·kg^?1·min^?1 for BASE, CRE + CAF and CRE + PLA, respectively; P>0.05) and absolute [Vdot]O_2max (3.6±0.4, 3.7±0.4 and 3.5±0.5 l·min^?1 for BASE, CRE + CAF and CRE + PLA, respectively; P>0.05). Blood samples indicated significantly higher blood lactate and glucose concentrations in the CRE + CAF among those in the BASE or CRE + PLA condition during the test (P<0.05). The time to exhaustion on a cycling ergometer was significantly longer for CRE + CAF (1087.2±123.9 s) compared with BASE (1009.2±86.0 s) or CRE + PLA (1040.3±96.1 s). This study indicated that a single dose of caffeine following short-term creatine supplementation did not hinder the creatine–caffeine interaction. In fact, it lengthened the time to exhaustion during an incremental maximum exercise test. However, this regime might lead to the accumulation of lactate in the blood.     

The effect of acute caffeine ingestion on upper body anaerobic exercise and cognitive performance

Abstract

The current study examined the effect of acute caffeine ingestion on mean and peak power production during upper body Wingate test (WANT) performance, rating of perceived exertion, readiness to invest effort and cognitive performance. Using a double-blind design, 12 males undertook upper body WANTs, following ingestion of caffeine (5?mg*kg^?1) or placebo. Pre-substance ingestion, 60?mins post substance ingestion and post exercise participants completed measures of readiness to invest physical and mental effort and cognitive performance. Peak power was significantly higher (P?=?.026), fatigue index greater (P?=?.02) and rating of perceived exertion lower (P?=?.025) in the presence of caffeine. Readiness to invest physical effort was also higher (P?=?.016) in the caffeine condition irrespective of time point (pre, 60?mins post ingestion and post exercise). Response accuracy for incongruent trials on the Flanker task was superior in the presence of caffeine (P?=?.006). There was a significant substance?×?time interaction for response speed in both congruent and incongruent conditions (both P?=?.001) whereby response speeds were faster at 60?mins post ingestion and post exercise in the caffeine condition, compared to placebo. This is the first study to examine the effects of caffeine ingestion on this modality of exercise and suggests that caffeine ingestion significantly enhances peak power, readiness to invest physical effort, and cognitive performance during WANT performance.