发展战略性新兴产业的研究与思考——以安徽省马鞍山磁性材料产业发展为例

近年来,发展战略性新兴产业方兴未艾,如何结合各地实际培育和发展战略性新兴产业,地方政府进行了一系列的探索和实践.本文深入剖析了安徽省马鞍山市磁性材料产业发展现状及发展瓶颈,提出了马鞍山市磁性材料产业发展要准确定位、拓宽融资渠道、促进自主创新、优化产业发展环境等对策,并认为各地发展战略性新兴产业要注重培育和改造提升两手抓、以创新驱动发展、加强产业载体建设、不断优化产业发展环境.     

大学生网络成瘾问题心理干预个案研究

采用个案研究法,选取网络成瘾的Z同学为干预对象。通过质性与量化的心理评估,制定出合理的干预计划和策略。通过四个阶段的认知行为疗法心理干预,取得理想的效果。这可为大学生网络成瘾心理干预提供可借鉴的思路和经验。     

Therapeutic radionuclides in nuclear medicine: current and future prospects

The potential use of radionuclides in therapy has been recognized for many decades. A number of radionuclides, such as iodine-131 (¹³¹I), phosphorous-32 (³²P), strontium-90 (⁹⁰Sr), and yttrium-90 (⁹⁰Y), have been used successfully for the treatment of many benign and malignant disorders. Recently, the rapid growth of this branch of nuclear medicine has been stimulated by the introduction of a number of new radionuclides and radiopharmaceuticals for the treatment of metastatic bone pain and neuroendocrine and other malignant or non-malignant tumours. Today, the field of radionuclide therapy is enjoying an exciting phase and is poised for greater growth and development in the coming years. For example, in Asia, the high prevalence of thyroid and liver diseases has prompted many novel developments and clinical trials using targeted radionuclide therapy. This paper reviews the characteristics and clinical applications of the commonly available therapeutic radionuclides, as well as the problems and issues involved in translating novel radionuclides into clinical therapies.     

医学生心理健康问题与图书馆阅读疗法

文章对医学生心理健康与心理健康教育的现状进行了分析,认为目前我国大学生的心理健康教育缺乏专业的心理健康教育团队,心理健康教育课程也不完善,并且缺乏综合性的管理机制;论证了图书馆阅读疗法对于当今的医学生心理健康教育的可行性,提出了开展阅读疗法的具体措施。     

由力学变分原理到定态电磁场变分原理

本文以力学变分原理为基础,引出时空算子对偶概念,据以导出定态电磁场变分原理;进而,论述了时空淡化和磁单极子问题。     

Physical Activity Indicators,Metabolic Biomarkers,and Comorbidity in Type 2 Diabetes

ABSTRACT

Purpose: This study aimed (1) to compare physical activity (PA) indicators, metabolic biomarkers, and comorbidity, (2) to investigate the relationship between PA indicators and metabolic biomarkers, comorbidity and (3) to identify barriers to PA in patients with type 2 diabetes (T2DM) who are using oral hypoglycaemic agent (OHA) or combined OHA and insulin (OHAiN). Methods: Sixty-one patients were classified as patients using only OHA or combined OHAiN. Metabolic biomarkers (waist-to-hip ratio, body mass index (BMI), lipid profile, glycosylated haemoglobin (HbA1c), fasting blood glucose, comorbidity and PA indicators (self-reported PA, number of steps (NOS), 6-minute walking distance (6MWD)) were assessed. PA perceptions and reasons for inactivity were questioned. Results: The comorbidity (p = .013), low-density lipoprotein-cholesterol (p = .026), total cholesterol (p = .008) and HbA1c (p = .020) were higher and PA level was lower (p = .007) in the OHAiN group. NOS was positively correlated with high-density lipoprotein-cholesterol (p = .037) and negatively correlated with BMI (p = .007). 6MWD was negatively correlated with BMI (p = .014) and comorbidity (p = .004) in the OHA group. BMI was a significant predictor of NOS (adjusted R² = 0.242) and comorbidity for 6MWD (adjusted R² = 0.250) in the OHA group. The majority of the patients (OHA = 34.3%, OHAiN = 42.3%) reported “lack of time” as the most common barrier to PA. Conclusions: This study showed that patients on OHAiN have lower PA levels, poorer metabolic profiles, and higher comorbidity rates than OHA users. PA indicators were related with some metabolic biomarkers and comorbidity in only OHA users. The most common reason for inactivity was “the lack of time” in both groups.     

分段逆向调强优化方法在乳腺癌调强放疗计划设计中的应用研究

目的:制作乳腺癌调强放疗计划时,采用分段逆向调强优化方法以达到更好的靶区剂量和保护肺、心脏等危及器官。方法:应用Eclipse8.6计划系统针对10例乳腺癌患者(肿瘤原发部位左右侧各5例)分别制定T1,T2模式调强放疗计划,处方剂量均为DT50Gy/25次。T1模式采用左乳300°、330°、0°、30°、60°、90°和120°方向射野,右乳60°、30°、0°、330°、300°、270°和240°方向射野,设置优化参数进行逆向优化和剂量运算。T2模式采用与T1模式相同的角度方向设野,第一段总剂量24Gy,分次剂量2Gy,分12次治疗,设置优化参数进行逆向优化和剂量运算;第二段总剂量26Gy,分次剂量2Gy,分13次照射,设置优化参数,采用"Base dose plan"功能选择基于第一段治疗计划以总量50Gy来逆向优化和剂量运算。将两段计划相加作为T2模式的治疗计划,通过剂量体积直方图比较两种模式下计划的靶体积和危及器官剂量分布。结果:T1、T2模式调强放疗计划的靶体积均满足临床剂量要求,对于左侧乳腺癌,适形指数分别为0.727±0.034、0.751±0.034(t=-6.20,P=0.003);对于右侧乳腺癌,适形指数分别为0.691±0.058、0.729±0.048(t=-5.39,P=0.006)。对左侧乳腺癌,T2模式的左肺V10(%)、左肺V20(%)、左肺V30(%)、全肺V10(%)、全肺V20(%)、全肺V30(%)和心脏V10(%)均大于T1模式,分别增大5.0%、2.7%、3.7%、4.6%、2.6%、3.8%和4.4%。对于右侧乳腺癌,无充分证据说明危及器官各指标有差别。结论:与T1模式相比,采用分段逆向调强优化方法能更好的优化靶区的剂量分布,但对左侧乳腺癌而言,会略微增加左肺、全肺和心脏剂量受量。     

基于专利地图的治疗型超声竞争情报挖掘

通过专利地图分析专利信息,可以挖掘技术热点,预测技术发展方向,确定竞争对手及其地位。以治疗型 超声专利为例,通过对所有在我国申请的该类发明专利的统计,利用时间序列、统计频次、聚类等方法,绘制各类专利 地图,最终以鱼骨图这种可视化的方式进行汇总,直接展示情报分析结果,挖掘治疗型超声的相关竞争情报。将鱼骨图 与专利地图结合起来对专利情报进行分析,可以将竞争环境、竞争对手、研究热点等有效因素进行有条理的可视化展现。     

Human biochemical genetics： an insight into inborn errors of metabolism

Inborn errors of metabolism （IEM） include a broad spectrum of defects of various gene products that affect intermediary metabolism in the body. Studying the molecular and biochemical mechanisms of those inherited disorder, systematically summarizing the disease phenotype and natural history, providing diagnostic rationale and methodology and treatment strategy comprise the context of human biochemical genetics. This session focused on： （1） manifestations of representative metabolic disorders; （2） the emergent technology and application of newborn screening of metabolic disorders using tandem mass spectrometry; （3） principles of managing IEM; （4） the concept of carrier testing aiming prevention. Early detection of patients with IEM allows early intervention and more options for treatment.