绿茶提取物抗氧化的研究及在冰淇淋中的应用

通过对DPPH自由基的清除能力和还原力的测定,研究绿茶提取物的抗氧化活性;通过测定膨胀率、融化率及硬度等指标,研究添加绿茶提取物冰淇淋的品质特性.结果表明,绿茶提取物具有较强的清除自由基和抑制自由基引起的氧化损伤的能力;添加绿茶提取物冰淇淋的膨胀率和抗融化性要优于普通冰淇淋.     

不同负荷运动训练对大鼠红细胞膜特性的影响

对大鼠进行一个月的运动训练发现，大、小两种不同负荷的训练可造成红细胞膜氧化、抗氧化能力的变化，进而对其整体机能产生不同的影响。通过本实验研究得出以下结论：①一次急性运动可造成红细胞的破坏增多，但小负荷的运动训练可以通过增强机体的抗氧化能力，改善红细胞膜性能等途径，使其有氧代谢能力及抵抗力竭运动造成损伤的能力均提高．大负荷的训练结果不但使红细胞的破坏增加，且单个红细胞的机能也明显下降，在训练结束后可能发生运动贫血。②大负荷训练后侧流动性下降，与其MDA含量及SOD活性的变化高度相关。     

有氧运动及芦荟对糖尿病大鼠肝脏抗氧化酶活性的影响

目的：研究有氧运动结合补充芦荟对糖尿病大鼠肝脏抗氧化酶活性的影响。方法：注射链脲佐菌素诱导成年雄性sD大鼠造成糖尿病模型，以观察有氧运动、补充芦荟、有氧运动结合补充芦荟对糖尿病大鼠肝脏SOD、GSH—Px、CAT、MDA的影响。结果：经8周实验后，各干预组肝脏SOD、GSH—Px、CAT活性显著高于糖尿病安静组（P〈0．05），MDA含量显著低于糖尿病安静组（P〈0．05），其中以有氧运动结合补充芦荟组变化最明显。结论：有氧运动及补充芦荟能明显提高糖尿病大鼠肝脏抗氧化酶活性，降低脂质过氧化程度，保护肝脏的超微结构不受自由基的攻击，确保肝脏正常发挥调节糖代谢的功能。     

运动对抗氧化系统的影响

介绍了自由基的产生及对人体的危害,并全面论述了运动与自由基的关系。指出应根据年龄,选择适当的体育运动,以减少自由基损害;通常长期有氧代谢运动可激活人体抗氧化酶的活性并提高酶的合成量,清除新陈代谢和剧烈运动时产生的大量自由基,降低细胞LPO水平,预防衰老,增进健康。     

运动与自由基研究的新进展

随着自由基理论在运动医学领域受到日益关注，运动与自由基研究已成为运动医学界一个重要课题，此领域的研究主要集中于：运动性内源自由基代谢、自由基与运动性疲劳、自由基与运动性肌肉损伤、抗氧化剂在运动训练中的应用以及抗氧化的运动性适应。该文就此领域的进展做一简要综述。     

有氧锻炼对中老年妇女抗氧化能力的影响

以木兰拳习练者为研究对象 ,观察木兰拳运动对中老年妇女体内抗氧化酶水平和自由基代谢情况的影响 ,认为经常参加木兰拳锻炼能有效地降低血清MDA及LDL -C的水平 ,提高机体内血清GSH水平 ,增强中老年妇女的抗氧化能力 ,加强机体对自由基清除 ,维持血脂正常水平 ,预防动脉粥样硬化的发生。     

中药补剂与运动能力

从中药补剂的抗氧化抗疲劳、调节机体免疫能力以及对运动能力的影响三个方面入手，系统地阐述了中药补剂对运动能力的影响以及作用机理，剖析了中药补剂的研究现状，并预测了中药补剂的发展前景，为开发中药补剂提供理论依据及应用方法。     

有氧运动训练延缓小鼠大脑老化的生化研究

通过对小鼠大脑线粒体形态功能及抗氧化水平的观察研究，旨在探讨大脑老化的过程、机理及有氧运动对其的影响。研究发现，老龄小鼠大脑线粒体数量减少、体积增大，呼吸链酶活性下降，氧化与抗氧化系统失衡，脂褐素含量增多；有氧运动训练能增强大脑抗氧化防御机能，延缓大脑线粒体伴随衰老出现的能量转换效率的下降。     

松针提取液对小鼠心肌、肝脏、股四头肌自由基代谢的影响

选取40只昆明种小鼠随机分成安静组和训练组,两组又分设对照组和松针提取液组.服药组小鼠短期连续服用松针提取液,20天后小鼠力竭游泳造成疲劳,测定心肌、肝脏、股四头肌超氧化物歧化酶（SOD）、总抗氧化能力（T-AOC）和丙二醛（MDA）等指标.结果：心肌、肝脏、股四头肌超氧化物歧化酶（SOD）和总抗氧化能力（T-AOC）的活性均有显著性升高,心肌、肝脏、股四头肌丙二醛（MDA）含量显著性降低.结论：松针提取液具有保护心肌、肝脏、股四头肌免受自由基损伤的功能.     

Oxidative stress and damage induced by abnormal free radical reactions and IgA nephropathy

Objective: To estimate the oxidative stress and oxidative damage induced by abnormal free radical reactions in IgA nephropathy (IgAN) patients' bodies. Methods: Seventy-two IgA N patients (IgANP) and 72 healthy adult volunteers (HAV) were enrolled in a random control study design, in which the levels of nitric oxide (NO) in plasma, lipoperoxide (LPO) in plasma and in erythrocytes, and vitamin C (VC), vitamin E (VE) and β-carotene (β-CAR) in plasma as well as the activities of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX) in erythrocytes were determined with spectrophotometric mothods. Results: Compared with the HAV group, the averages of NO in plasma, and LPO in plasma and in erythrocytes in the IgANP group were significantly increased (P＜0.0001), while those ofVC, VE and β-CAR in plasma as well as those of SOD, CAT and GPX in erythrocytes in the IgANP group were significantly decreased (P＜0.0001). Linear correlation analysis showed that with the increase of the values of NO, and LPO in plasma and in erythrocytes, and with the decrease of those ofVC, VE, β-CAR,SOD, CAT and GPX in the IgAN patients, the degree of histological damage of tubulointerstitial regions was increased gradually (P＜0.0001); and that with the prolongation of the duration of disease the values of NO, and LPO in plasma and erythrocytes were increased gradually, while those of VC, VE, β-CAR, SOD, CAT and GPX were decreased gradually (P＜0.005). The discriminatory correct rates of the above biochemical parameters reflecting oxidative damage of the IgAN patients were 73.8%-92.5%, and the correct rates for the HAV were 70.0%-91.3% when independent discriminant analysis was used; and the correct rate for the IgAN patients was increased to 98.8%, the correct rate for the HAV was increased to 100% when stepwise discriminant analysis was used. The above biochemical parameters' reliability coefficient (alpha) were used to estimate the oxidative damage of the IgAN patients as 0.8145, the standardized item alpha=0.9730, F=53273.5681, P＜0.0001. Conclusions: A series of free radical chain reactions caused serious pathological aggravation in the IgANP' bodies, thus resulting in oxidative damage in their bodies. In treating IgANP, therefore, it is necessary that suitable dose antioxidants should be supplemented to them so as to alleviate the oxidative damage in their bodies.