Science Letters： Brain natriuretic peptide： A potential indicator of cardiomyogenesis after autologous mesenchymal stem cell transplantation？

We observed in a pilot study that there was a transient elevation of brain natriuretic peptide （BNP） level shortly after the transplantation in the patient with ischemic heart failure, which is unexplainable by the simultaneous increase of the cardiac output and six-minute walk distance. Similar findings were observed in the phase I trial. We postulated on the basis of the finding of Fukuda in vitro that this transient elevation of BNP level against the improvement of cardiac function and exercise capacity might indicate cardiomyogenesis in patients after mesenchymal stem cell transplantation. Further study is warranted to verify the hypothesis.     

Baseline Intraocular Pressure Is Associated With Subjective Sensitivity to Physical Exertion in Young Males

Purpose: The purposes of this study were to (a) investigate the effect of physical effort (cycling for 60 min at 60 ± 5% of individually computed reserve heart-rate capacity), combined with 2 different levels of cognitive demand (2-back, oddball), on intraocular pressure (IOP) and subjective judgments of perceived exertion (ratings of perceived exertion [RPE]), affect (Affective Valence subscale of the Self-Assessment Manikin [SAM]), and mental workload (National Aeronautics and Space Administration Task Load Index [NASA-TLX]); and (b) ascertain whether baseline IOP, measured before exercise, is associated with individual differences in subjective assessments of effort and affective response during exercise. Method: Seventeen participants (M_age = 23.28 ± 2.37 years) performed 2 physical/cognitive dual tasks, matched in physical demand but with different mental requirements (2-back, oddball). We assessed IOP before exercise, after 2 min of active recovery, and after 15 min of passive recovery, and we also collected RPE and SAM measures during the sessions (28 measurement points). We used NASA-TLX and cognitive performance as checks of the mental manipulation. Results: (a) Intraocular pressure increased after concomitant physical/mental effort, with the effect reaching statistical significance after the 2-back task (p = .002, d = 0.35) but not after the oddball condition (p = .092, d = 0.29). (b) Baseline IOP was associated with subjective sensitivity to effort and showed statistical significance for the oddball condition (p = .03, ?_p² = .622) but not for the 2-back task (F < 1). Conclusions: Results suggest a relationship between IOP and physical/cognitive effort, which could have implications for the management of glaucoma. Additionally, a rapid measure of IOP could be used as a marker of individual effort sensitivity in applied settings.     

Effects of weightlifting exercise,traditional resistance and plyometric training on countermovement jump performance: a meta-analysis

Jump performance is considered an important factor in many sports. Thus, strategies such as weightlifting (WL) exercises, traditional resistance training (TRT) and plyometric training (PT) are effective at improving jump performance. However, it is not entirely clear which of these strategies can enable greater improvements on jump height. Thus, the purpose of the meta-analysis was to compare the improvements on countermovement jump (CMJ) performance between training methods which focus on WL exercises, TRT, and PT. Seven studies were included, of which one study performed both comparison. Therefore, four studies comparing WL exercises vs. TRT (total n = 78) and four studies comparing WL exercises vs. PT (total n = 76). The results showed greater improvements on CMJ performance for WL exercises compared to TRT (ES_diff: 0.72 ± 0.23; _95%CI: 0.26, 1.19; P = 0.002; Δ % = 7.5 and 2.1, respectively). The comparison between WL exercises vs. PT revealed no significant difference between protocols (ES_diff: 0.15 ± 0.23; _95%CI: ?0.30, 0.60; P = 0.518; Δ % = 8.8 and 8.1, respectively). In conclusion, WL exercises are superior to promote positive changes on CMJ performance compared to TRT; however, WL exercises and PT are equally effective at improving CMJ performance.     

有氧运动的历史——历经50年，仍在前进中

《有氧运动》出版至今已有50年,追溯过去,我从未想过医生对于运动在医学实践中价值的态度会发生翻天覆地的变化。在我的一生中,我从未想到能见证平板测试成为完整检查的必要组成部分,没想到缺乏身体活动的重要性影响可与高血压和高胆固醇齐平,也没想到吸烟会被认为是影响冠状动脉的危险因素。本文介绍了在我和本领域许多同事的工作以及库珀研究中心（The Cooper Institute）的重要工作的影响下,这种缓慢但渐进的转变是如何发生的。1970年6月,我租用了一个研究所,也就是后来的库珀诊所（Cooper Clinic）,半年之后,我在那里见到了我的第一个病人,现在库珀中心纵向研究作为世界上最大的比较测量健康水平的数据库,我们不再需要依赖问卷调查和从发表的700多篇学术文献中找寻健身与健康的关联,我们已经证明并且可以有把握地说,“运动是良医”,更具体地说,我希望本文能够展示我们和其他人在这项科学研究中所做的工作,此外,即使是最严厉的批评者现在也在说,“这些结果令人印象深刻,不容忽视。”     

The effect of 10 days of intermittent fasting on Wingate anaerobic power and prolonged high-intensity time-to-exhaustion cycling performance

Many physically active individuals have undertaken intermittent fasting to reduce their daily caloric intake. However, abstaining from meals for a specific length of time may lead to the acute disturbance of highly carbohydrate-dependent exercise performance. The purpose of this study was to observe the effect of 10 days of intermittent fasting on high-intensity type exercises, Wingate anaerobic (WT) and prolonged high-intensity time-to-exhaustion (HIT) cycling test. Twenty participants were randomised into an intermittent fasting (FAS) and a control group (CON). One day after baseline data collection on Day-0 where participants consumed their recommended daily caloric intake (FAS?=?2500?±?143?kcal?day^?1; CON?=?2492?±?20?kcal?day^?1) served over a course of five meals, the FAS group consumed only four meals where 40% was restricted by the omission of lunch (FAS?=?1500?±?55?kcal?day^?1). This diet was then continued for 10 days. Data on exercise performance and other dependent variables were collected on Day-2, -4, -6, -8 and -10. A reduction in WT power in the FAS group was observed on Day-2 (821.74?±?66.07?W) compared to Day-0 (847.63?±?95.94?W) with a moderate effect size (p?p?p?相似文献   

Repeated-sprint performance and plasma responses following beetroot juice supplementation do not differ between recreational,competitive and elite sprint athletes

Purpose: There is an ongoing debate whether highly trained athletes are less responsive to the ergogenic properties of nitrate. We assessed the effects of nitrate supplementation on plasma nitrate and nitrite concentrations and repeated-sprint performance in recreational, competitive and elite sprint athletes. Methods: In a randomized double-blinded cross-over design, recreational cyclists (n?=?20), national talent speed-skaters (n?=?22) and Olympic-level track cyclists (n?=?10) underwent two 6-day supplementation periods; 140?mL/d nitrate-rich (BR; ～800?mg/d) and nitrate-depleted (PLA; ～0.5?mg/d) beetroot juice. Blood samples were collected and three 30-s Wingate tests were performed. Results: Plasma nitrate and nitrite concentrations were higher following BR vs PLA (P?P?>?.10). Peak power over the three Wingates was not different between BR and PLA (1338?±?30 vs 1333?±?30 W; P?=?.62), and there was no interaction between treatment (BR-PLA) and Wingate number (1-2-3; P?=?.48). Likewise, mean power did not differ between BR and PLA (P?=?.86). In contrast, time to peak power improved by ～2.8% following BR vs PLA (P?=?.007). This improvement in BR vs PLA was not different between Wingate 1, 2 and 3. Moreover, the effects of BR vs PLA did not differ between sport levels for any Wingate parameter (all P?>?.30). Conclusion: The plasma and repeated-sprint performance responses to beetroot juice supplementation do not differ between recreational, competitive and elite sprint athletes. Beetroot juice supplementation reduces time to reach peak power, which may improve the capacity to accelerate during high-intensity and sprint tasks in recreational as well as elite athletes.     

A systematic review of siblings and physical activity experiences

Siblings are important developmental agents, yet understanding of their influence in physical activity settings is limited. Prior to developing sibling-focused research questions, a comprehensive summary of the diverse literature regarding siblings in the physical domain is needed. A systematic review of siblings in physical activity contexts was conducted to gauge current knowledge on this topic and provide a guide for future empirical endeavors. A comprehensive literature search of CINAHL, The Cochrane Library, PsychINFO, PubMed, SPORTDiscus, and Web of Science yielded 68 studies spanning 46 years (1970–2016). The results showed siblings to be actively and passively associated with physical activity levels and to be sources of both positive and negative experiences in sport. The sex composition of sibling dyads appears to moderate outcomes. Overall, the findings provide an outline of sibling-based subject areas, identify topics needing further attention, and showcase methods with potential to advance the study of sibling relationships in the physical domain.     

Tai Ji Quan as antihypertensive lifestyle therapy: A systematic review and meta-analysis

BackgroundProfessional health organizations are not currently recommending Tai Ji Quan alongside aerobic exercise to treat hypertension. We aimed to examine the efficacy of Tai Ji Quan as antihypertensive lifestyle therapy.MethodsTai Ji Quan interventions published in English and Chinese were included when they involved healthy adults, reported pre- and post-intervention blood pressure (BP), and had a non-exercise/non-diet control group. We systematically searched 11 electronic databases for studies published through July 31, 2018, yielding 31 qualifying controlled trials. We (1) evaluated the risk of bias and methodological study quality, (2) performed meta-regression analyses following random-effects assumptions, and (3) generated additive models representing the largest possible clinically relevant BP reductions.ResultsParticipants (n = 3223) were middle-aged (56.6 ± 15.1 years of age, mean ± SD) adults with prehypertension (systolic BP (SBP) = 136.9 ± 15.2 mmHg, diastolic BP (DBP) = 83.4 ± 8.7 mmHg). Tai Ji Quan was practiced 4.0 ± 1.4 sessions/week for 54.0 ± 10.6 min/session for 22.3 ± 20.2 weeks. Overall, Tai Ji Quan elicited significant reductions in SBP (–11.3 mmHg, 95%CI: –14.6 to –8.0; d₊ = –0.75) and DBP (–4.8 mmHg, 95%CI: –6.4 to –3.1; d₊ = –0.53) vs. control (p < 0.001). Controlling for publication bias among samples with hypertension, Tai Ji Quan trials published in English elicited SBP reductions of 10.4 mmHg and DBP reductions of 4.0 mmHg, which was half the magnitude of trials published in Chinese (SBP reductions of 18.6 mmHg and DBP reductions of 8.8 mmHg).ConclusionOur results indicate that Tai Ji Quan is a viable antihypertensive lifestyle therapy that produces clinically meaningful BP reductions (i.e., 10.4 mmHg and 4.0 mmHg of SBP and DBP reductions, respectively) among individuals with hypertension. Such magnitude of BP reductions can lower the incidence of cardiovascular disease by up to 40%.     

长江三角洲地区城市社区群众体育若干问题思考

长三角是我国经济、文化和教育事业最为发达的地区,随着改革开放的不断深入,各项事业蒸蒸日上,群众社区体育也呈现出一片欣欣向荣的景象,但在发展的过程中,同样也遇到了一些困惑。为此,提出长三角社区发展的新内涵;同时提出长三角城市社区体育持续发展需要解决的问题。