突出特色 构建“校企结合、学工衔接”人才培养模式

"校企结合、学工衔接"是学校根据自身办学历史和行业办学的实际情况探索出的适合自身发展需要的学校人才培养模式。分析了"校企结合、学工衔接"人才培养模式的特征和构建此种模式应注意的问题。     

Combination of Se-methylselenocysteine,D-α-tocopheryl succinate, β-carotene,and L-lysine can prevent cancer metastases using as an adjuvant therapy

ObjectivePrimary tumor treatment through surgical resection and adjuvant therapy has been extensively studied, but there is a lack of effective strategies and drugs for the treatment of tumor metastases. Here, we describe a functional product based on a combination of compounds, which can be used as an adjuvant therapy and has well-known mechanisms for inhibiting cancer metastases, improving anti-cancer treatment, and enhancing immunity and antioxidant capacity. Our designed combination, named MVBL, consists of four inexpensive compounds: L-selenium-methylselenocysteine (MSC), D-‍α‍-tocopheryl succinic acid (VES), β‍-carotene (β‍-Ca), and L-lysine (Lys).MethodsThe effects of MVBL on cell viability, cell cycle, cell apoptosis, cell migration, cell invasion, reactive oxygen species (ROS), and paclitaxel (PTX)-combined treatment were studied in vitro. The inhibition of tumor metastasis, antioxidation, and immune enhancement capacity of MVBL were determined in vivo.ResultsMVBL exhibited higher toxicity to tumor cells than to normal cells. It did not significantly affect the cell cycle of cancer cells, but increased their apoptosis. Wound healing, adhesion, and transwell assays showed that MVBL significantly inhibited tumor cell migration, adhesion, and invasion. MVBL sensitized MDA-MB-231 breast cancer cells to PTX, indicating that it can be used as an adjuvant to enhance the therapeutic effect of chemotherapy drugs. In mice, experimental data showed that MVBL inhibited tumor metastasis, prolonged their survival time, and enhanced their antioxidant capacity and immune function.ConclusionsThis study revealed the roles of MVBL in improving immunity and antioxidation, preventing tumor growth, and inhibiting metastasis in vitro and in vivo. MVBL may be used as an adjuvant drug in cancer therapy for improving the survival and quality of life of cancer patients.     

组合训练法在高校足球教学中的应用研究

随着时代的不断发展和教育体系的改革,教学中强调培养学生"德、智、体、美、劳"的全面发展,在教学中重视学生素质的培养。足球作为主要的体育类型之一,其在高校教学中起到了重要的作用,是培养学生综合素质的基础保障。由此可见,在高校所有教学活动中足球教学意义重大,不仅能够提升学生的身体素质,还能够改善学生的学习状态。就组合训练法而言,其是高校足球教学中常用的教学方法,该方法的应用能够有效地提高足球教学质量,还能够提升学生的专业水平。     

竞技体育如何与大学生高水平田径运动队相结合

运用访问调查等研究方法，对我国大学生高水平田径运动队的目前竞技水平进行了剖析，探求使竞技体育与大学生高水平运动队相结合的途径、方法。通过建立科学的、行之有效的大学生体育运动竞赛管理体制，调整人才机构，实行教练员岗位竞争机制，提高运动员选材质量和体育经费社会化、信息科学化制度等多种途径，形成我国特有的大学生高水平运动训练竞技人才的培养体制是解决问题的关键所在。     

数与形

通过几个例子阐述了数与形的密切联系,“形”给出了“数”的几何直观,“数”揭示了“形”的本质特征,用数形结合的方法去解决一些数学问题,可使问题很快得到解决,有的数学问题,只有通过形才能得到解决。     

重为教育理论辩护

重新对教育理论进行辩护,对教育理论进行正确认识.对教育理论与教育实践分裂的原因和时间进行了分析,指出了教育理论肯定可以和教育实践统一.     

谈诗与画的结合

诗与画虽属艺术的两种不同的表现形式 ,但二者的关系极为密切。本文试就诗与画的结合做一些探讨     

基于特定零件的组合钻床改造设计

从企业实际需求出发,在全面分析被加工零件的基础上,指出采用现有设备的不足,不仅工人劳动强度大,而且生产率低,不利于保证零件加工精度.研制出了16孔单工位组合钻床,解决了上述问题.     

Combining gene sequence similarity and textual information for gene function annotation in the literature

Annotation of the functions of genes and proteins is an essential step in genome analysis. Information extraction techniques have been proposed to obtain the function information of genes and proteins in the biomedical literature. However, the performance of most information extraction techniques of function annotation in the biomedical literature is not satisfactory due to the large variability in the expression of concepts in the biomedical literature. This paper proposes a framework to improve the gene function annotation in the literature by considering both the textual information in the literature and the functions of genes with sequences similar to a target gene. The new framework collects multiple types of evidence as: (i) textual information about gene functions by matching keywords of the gene functions; (ii) gene function information from the known functions of genes with sequences similar to a target gene; and (iii) the prior probabilities of gene functions to be associated with an arbitrary gene by mining the known gene functions from curated databases. A supervised learning method is utilized to obtain the weights for combining the three types of evidence to assign appropriate Gene Ontology terms for target genes. Empirical studies on two testbeds demonstrate that the combination of sequence similarity scores, function prior probabilities and textual information improves the accuracy of gene function annotation in the literature. The F-measure scores obtained with the proposed framework are substantially higher than the scores of the solutions in prior research.

Territorial Rights and Wrongs

In this short article, Henry Rosenbloom, the founder of Australian independent publisher Scribe, complains about the tactic of UK-based publishers buying ‘Commonwealth’ rights and preventing Australian publishers from acquiring separate Australian rights. ‘UK publishers are not entitled to Australia as a territory. It is our country, our market, and our industry,’ he writes. This article was originally published in The Age newspaper in early 2008, then on Rosenbloom’s blog, and it was the catalyst for a spirited debate at this year’s London Book Fair.