汉代循吏的行政风范

汉代循吏在历史上是颇具人格魅力的一批官员。他们在注重发展地方经济、关心百姓疾苦、积极传播儒家文化的同时,还以身作则,清正廉洁,遵守法律,深得朝廷的认可和百姓的尊敬与爱戴。     

基于ASP.NET的时间服务平台的设计与实现

基于ASP.NET技术构建时间服务平台,充分发挥服务平台的网络效益,供大学生进行时间租赁、存储或时间交换。简要叙述平台的业务流程、数据模型、基于ADO.NET的数据库实现以及信用认证方法。     

DS18B20在车载时钟系统中的应用

随着我国汽车产业生产消费的快速发展,将电子产品加载到汽车上已逐渐成为汽车后市场的首选新装备,本文侧重研究具有系统稳定性与实时信息数据处理精确性的车载时钟控制系统,将DS18B20应用于传统的车载时钟系统,通过单片机实现控制,在Proteus仿真平台验证了系统运行的准确性与可靠性。系统硬件简单可靠,成本低,软件编程容易,可方便地移植。     

浅谈交叉线与直通线的做法及使用

本文主要介绍了我们在日常的网络布线中常用到的两种网线：交叉线与直通线．通过介绍交叉线与直通线的区别（其中主要讲解了两种网线的不同排序）、交叉线与直通线的做法及其各自的适用场合,使用户对这两种网线有了一个全面地了解,从而为用户在实际布线中如何选用这两种网线提供了参考．     

影子培训对校长专业发展的影响

校长培训作为开发校长人力资源、提升校长教育领导与管理能力的一项实践活动,正在受到社会各界的广泛重视。“教育部一中国移动中小学校长培训项目”影子培训在促进西部地区骨干中小学校长教育管理水平的提高的过程中产生了积极的作用。     

基于B/S模式的机械类金工课程网络教学平台的建设

金工课程是机械大类的专业基础课,理论性、实践性和工艺性都很强,学习方法不易掌握.针对这一情况研究开发的机械类金工课程网络教学平台,旨在较好地帮助提高教与学的质量和效率,有效改善教学效果.     

浅析B2C服装电子商务企业如何吸引风险投资

初创期B2C服装电子商务企业高风险、高投入、高预期收益的特性使我国B2C服装电子商务企业在发展过程中时刻伴随着风险投资的身影,但如何吸引风险投资是B2C服装电子商务企业面临的一个难题。文章在分析风险投资选择项目的标准的基础上,从创业管理团队、商业模式两个方面论述了初创期B2C服装电子商务企业如何吸引风险投资。     

Concordance of apolipoprotein B concentration with the Friedewald,Martin-Hopkins,and Sampson formulas for calculating LDL cholesterol

IntroductionTwo new formulas, the Martin-Hopkins and the Sampson formula, were recently developed to overcome shortcomings of the Friedewald formula for calculating LDL-cholesterol. We aimed to compare the concordance of the two formulas with apolipoprotein B (apoB), a surrogate marker of the number of LDL particles.Materials and methodsIn a study of serum lipid data of 1179 patients who consulted the AZ St-Jan Hospital Bruges for cardiovascular risk assessment, the correlation and concordance of the Friedewald, Martin-Hopkins and Sampson formulas with apoB concentration, measured by immunonephelometry, were determined and compared.ResultsThe Martin-Hopkins formula showed significantly higher correlation coefficient than the Friedewald formula with apoB in the entire dataset and in patients with low LDL-cholesterol < 1.8 mmol/L. Both Martin-Hopkins and Sampson formulas yielded > 70% concordance of LDL-cholesterol with regard to treatment group classification based on population-equivalent thresholds of apoB in hypertriglyceridemic patients (2-4.5 mmol/L), with the highest concordance (75.6%) obtained using Martin-Hopkins formula vs. 60.5% with Friedewald formula.ConclusionThe Martin-Hopkins (and, to a lesser extent, Sampson) formula is more closely associated with the number of LDL particles than Friedewald formula. This, in combination with literature evidence of lesser accuracy of the Friedewald formula, is an argument to switch from Friedewald to a modified, improved formula.     

Compensatory changes in physical activity and sedentary time in children and adolescents with cystic fibrosis

Physical activity (PA) is a key element in Cystic Fibrosis (CF) treatment strategies, yet little is known as to whether activity compensation occurs. This study examined whether PA and/or sedentary time on one day were temporally associated with time spent in these intensities the following day in youth with CF. Time spent sedentary and in different PA intensities were objectively-measured for seven consecutive days in 50 youth (22 boys; 12.0 ± 2.7 years); 25 with mild-to-moderate CF and 25 age- and sex-matched controls. Multilevel analyses (day and child) were conducted using generalised linear latent and mixed models. On any given day, every additional 10 minutes spent in sedentary time or moderate-to-vigorous physical activity (MVPA) were associated with 1.9 (95%CI: ?3.6 to ?1.2) and 12.4 (95%CI: ?22.1 to ?2.9) minutes less sedentary time the following day, respectively. These temporal associations were also observed when split by group (3.1 vs. 1.9 minutes for healthy and CF, respectively). These findings indicate that youth do not compensate their PA, irrespective of disease status, between days, but may compensate their sedentary time between days. Experimental studies are warranted to fully elucidate whether compensatory responses to PA and sedentary time occur, which is fundamental for informing PA promotion strategies.     

A case of vitamin B12 deficiency neurological syndrome in a young adult due to late-onset cobalamin C (CblC) deficiency: a diagnostic challenge

Vitamin B12 deficiency can present with neurologic and psychiatric symptoms without macrocytic anaemia. We describe a case of late-onset cobalamin C deficiency which typically presents with normal serum vitamin B12 concentrations, posing an additional diagnostic challenge. A 23-year-old woman with decreased muscle strength and hallucinations was diagnosed with ‘catatonic depression’ and admitted to a residential mental health facility. She was referred to our hospital for further investigation 3 months later. Heteroanamnesis revealed that the symptoms had been evolving progressively over several months. Magnetic resonance imaging (MRI) of the brain showed diffuse symmetrical white matter lesions in both hemispheres. Routine laboratory tests including vitamin B12 and folic acid were normal except for a slight normocytic, normochromic anaemia. Over the next 6 weeks her symptoms deteriorated, and she became unresponsive to stimuli. A new MRI scan showed progression of the white matter lesions. The neurologist requested plasma homocysteine (Hcys) which was more than 8 times the upper limit of normal. Further testing revealed increased methylmalonic acid and the patient was diagnosed with adult-onset cobalamin C deficiency. This case illustrates that Hcys and/or methylmalonic acid should be determined in patients presenting with neuropsychiatric symptoms suggestive of vitamin B12 deficiency with a normal serum vitamin B12 to rule out a late-onset cobalamin C deficiency.