中老年脂肪肝与高脂血症、糖尿病、高尿酸血症、高血压的相关性研究

对2003年9月湖州师范学院教职工体检的471位中老年教职工的脂肪肝与高脂血症、高血糖、高尿酸血症、高血压疾病的相关性进行分析研究．经统计学检验，发现脂肪肝组患高脂血症、高血糖、高尿酸血症、高血压疾病的患病率与非脂肪肝组的患病率比较有显著差异．分析认为：脂肪肝是由各种原因引起的肝脂肪蓄积过多的一种病理状态，脂肪肝与其并存的相关疾病虽然发病机制不同，但均属于生活习惯病，常合并存在，互相影响，且互为因果，彼此相关，严重地危害着中老年人的健康和生命，应当加强宣传和积极防治．     

自拟“参田方”治疗高血压病血脂升高的临床疗效观察与研究

目的旨在观察参田方在治疗高血压病血脂升高的疗效。方法将2005年7月到2007年7月岳阳市中医院的内科住院病人中符合高血压病和高血脂症的病人随机分为2组,观察2组病人使用参田方和尼群地平片．不同药物的治疗后血压和血脂的变化结果。结果参田方治疗组的降压效果显著优于对照组,降低高血压病患者血清总胆固醇、甘油三脂显著优于对照组。结论参田方组合治疗高血压病血脂升高疗效可靠,经得起重复。     

VEGFmRNA and eNOSmRNA expression in immature rabbits with bleomycin-induced pulmonary hypertension

Objective: To investigate the evolution of pulmonary hypertension, the pathological changes of pulmonaryarteries, and the expression of VEGFmRNA and eNOSmRNA of pulmonary arterial endothelial cells in immature rabbitstreated with intratracheal bleomycin (BLM). Methods: Immature rabbits were divided into control and BLM group. Twoand four weeks after intratracheal normal saline or BLM injection, the systolic, diastolic and mean pulmonary arterypressure (PASP, PADP, MPAP) were measured by micro-catheter; the pathological changes and the expression ofVEGFmRNA and eNOSmRNA of endothelial cells in pulmonary arteries were evaluated by HE and in situ hybridization.Results: Two and four weeks after intratracheal injection of BLM, the PASP, PADP and MPAP increased 53%, 49%, 52%in 2 weeks, and 43%, 89%, 56% in 4 weeks; the wall thickness increased and the cavity in middle and small pulmonaryarteries became narrow; the Thickness Index (TI) and Area Index (AI) increased 25%, 14% in 2 weeks, and 22%, 24% in 4weeks; the level of VEGFmRNA and eNOSmRNA expression decreased 46%, 43% in 2 weeks, and 43%, 51% in 4 weeks.There was no significant difference between 2 weeks and 4 weeks BLM groups. Conclusion: The pulmonary artery pressurewas elevated, the thickness of wall increased and the cavity became narrow in middle and small pulmonary arteries, and thelevel of VEGFmRNA and eNOSmRNA expression in pulmonary arterial endothelial cells decreased in immature rabbitsafter 2 weeks and 4 weeks of intratracheal 4 U/kg BLM injection.     

VEGFmRNA and eNOSmRNA expression in immature rabbits with bleomycin-induced pulmonary hypertension

INTRODUCTION Pulmonary hypertension is not rare in humanwith some heart and lung diseases. Chronic pul-monary hypertension leads to structural alterationsof the lung vessels. The pathophysiology of thisremodeling process is still poorly understood.Furthermore, the structural damage of the lungvessels limits the clinical success of vasodilatortreatment. Assuming genetic susceptibility, shearstress and inflammation are the principal pathoge-netic factors involved in lung vessel remode…     

家庭护理在老年高血压患者中的应用

目的：研究“以家庭为中心”的护理模式对缓解老年高血压患者的病情,促进老年高血压患者恢复以及缓解家庭焦虑的作用。方法：对老年高血压患者进行基础护理、生活护理、心理护理、健康教育以及健康指导。结论：家庭护理对老年高血压治疗效果明显。     

内皮素与心血管疾病的研究进展

内皮素由多种组织中的血管内皮细胞分泌,有强大持久的血管收缩效应,与高血压、高血脂、高血糖及心肌肥厚有密切的关系。综述了近10年来有关内皮素的研究进展,探讨血浆内皮素在心血管疾病发生发展中的作用以及运动对其影响,为心血管疾病的运动康复提供参考。