间歇性低氧训练对大鼠心肌、骨骼肌有氧代谢酶与运动能力的影响研究

本实验借助于动物模型,探讨间歇性低氧训练后心肌和骨骼肌有氧代谢酶的变化与运动能力的关系。实验结果显示:经低氧训练后,大鼠心肌和骨骼肌的线粒体氧化酶SDH和CCO活性明显高于平原对照组和平原训练组,低氧训练后的大鼠运动时间延长。提示心肌和骨骼肌有氧代谢酶活性增高是提高有氧运动能力的重要物质基础。     

循序渐进运动疗法治疗慢性疲劳症的相关研究

为研究循序渐进运动疗法对慢性疲劳症的治疗情况,将70名患者随机分为运动组和对照组,运动组进行循序渐进锻炼,对照组休息,记录治疗前后睡眠时间、生活质量问卷评分和心理、躯体症状问卷评分。结果发现循序渐进锻炼疗法能够有效和改善慢性疲劳症患者的症状,延长其睡眠时间、眼耳、肌肉骨骼系统和神经系统的症状明显好转,生活质量得到提高。     

Children with Down syndrome use phonological knowledge in reading

Contrary to the findings of Cossu, Rossini &Marshall [(1993a), Cognition 46: 129–138], the present experiment showed a clear link between phonological awareness and reading performance in children with Down syndrome. Although metaphonologicalperformance was lower in children with Downsyndrome than in normal controls of the samereading level, phonological awareness andreading were significantly correlated in bothgroups. However, children with Down syndromeremained deficient in skills such as rhymingwhich are not practised as a result ofliteracy. These results are discussed withinthe framework of Gombert's metalinguisticdevelopment theory where, on the basis of aninitial phonological sensitivity, alphabeticreading is a pacemaker for the development ofexplicit phonological awareness.     

昆虫抗药性分子机制

综述了国内外有关代谢相关酶系(包括细胞色素P450酶系,CYP6A1,CYP6A2,CYP6D,非特异性酯酶,醛氧化酶,谷胱甘肽S-转移酶等)变异产生的抗药性,以及农药靶标蛋白(包括乙酰胆碱酯酶,钠离子通道,γ-氨基丁酸(GA-BA)受体氯离子通道等)变异产生的抗药性方面的最新研究成果,并从分子水平阐明代谢抗性和靶标抗性产生的机制。     

早期牙隐裂的综合治疗及疗效观察

对42人47颗早期牙隐裂患牙,用作者提出的综合方法治疗后定期追踪2年以上,观察结果:总的牙齿保存率为95.74％,其中有26例患牙功能良好,临床检查和牙髓活力正常,结果提示:38.30％的早期牙隐裂患牙,其隐裂继续加深和开髓病变的发生均不易控制,宜及早做牙髓治疗和全冠修复。     

Association of physical activity with risk of metabolic syndrome: findings from a cross-sectional study conducted in rural area,Nantong, China

The prevalence of metabolic syndrome increases rapidly worldwide, and its association with physical activity (PA) varies with race and lifestyles. Little is known about the association in rural China. The Nantong Metabolic Syndrome Study recruited 13,505 female and 6997 male participants in 2007 and 2008. Socio-demographic characteristics, and physiological and behavioural data were collected. Logistic regression model was applied to estimate associations of metabolic syndrome and its components with different PAs. The overall metabolic syndrome prevalence was 21.6% in current study. Increasing total PA or moderate-to-vigorous-intensity occupational PA was associated with decreasing 5%–60% risk of having metabolic syndrome and abnormal metabolic syndrome components in both genders. An association between leisure-time PA and blood pressure was found in men, but no associations between leisure-time PA and metabolic syndrome components were found in women. Commuting PA, such as walking and taking bus, by bicycle and walking only, was associated with decrease of 20%–45% risk of several abnormal metabolic syndrome components in women. This study provides information for future investigation into the nature of these associations so that recommendations can be developed to reduce the prevalence of metabolic syndrome and its components among rural population in China.     

我国全民阅读调查分析与趋势预测

[目的/意义] 针对中国新闻出版研究院开展的全民阅读调查存在数据滞后的缺点,通过数据预测分析结果,为文化、教育、新闻、出版等部门进行文化供给侧改革与规划设计提供依据和重要参考。[方法/过程] 运用灰色预测模型,对2008-2014年全民阅读调查相关数据进行预测分析;经验证预测精度后,采用"新陈代谢灰色系统"改进模型再预测出2016-2023年相关数据。[结果/结论] 将2015年预测值与2015年实际调查值相比较,证明预测精度为优,表明通过系列模型预测的相关数据具有可靠性、实用性和创新性,可达到为相关部门提供依据和参考的要求。     

Transcription through chromatin — Link to diseases and therapeutics

The expression of chromosomal genes is regulated by posttranslational modification of both histone and nonhistone chromatin proteins and ATP-dependent remodeling of chromatin. Dysfunction of the modification and remodeling machineries can lead to several diseases, which include cancer, cardiac hypertrophy, and asthma. Many genetic diseases can also lead to malfunction of the machinery. The enzymes responsible for chromatin organization are the new targets for therapeutics. Inhibitors and activators of histone acetyltransferases and inhibitors of histone deacetylases may serve as new generation drugs.     

Examining the Connections between the Work We Do and Our Mental Health

ABSTRACT

Solving the issues brought forward in previous Hanna lectures and current discussion requires serious amounts of energy. This energy comes from individuals, working together, while also simultaneously working through internal struggles and challenges. Although small group and individual discussion can focus on mental health and burnout, these discussions have not been presented in public. There is little that kinesiology professionals do to discuss how self-care is approached, how to maintain or improve emotional well-being, and what happens when professionals burnout. A combination of personal experiences, research literature, and recommendations are discussed as a way to highlight the internal struggles that kinesiology professionals face while pursuing their work.     

三明治教学法在肾病综合症临床见习教学中的运用

目的:通过将三明治教学法应用于肾病综合征临床见习中,探讨三明治教学法在肾病综合征临床见习带教中的可行性。方法:选择桂林医学院2014级临床医学本科班为研究对象,从班级的学生抽取60人,分为2组,试验组为三明治教学模式,对照组为传统模式,分别讲授肾病综合征的相关知识,分析比较2组学生对教学效果的满意度。结果:试验组学生的教学效果的满意度明显优于对照组,差异有统计学意义。结论:三明治教学法能提高对教学效果的满意度,教学效果优于传统组。