A randomised trial comparing the efficacy and safety of topical ketoprofen in Transfersome® gel (IDEA-033) with oral ketoprofen and drug-free ultra-deformable Sequessome™ vesicles (TDT 064) for the treatment of muscle soreness following exercise

We compared the effectiveness of topical ketoprofen in Transfersome^® gel (IDEA-033) with oral ketoprofen and drug-free Sequessome? vesicles (FLEXISEQ^® Sport; TDT 064) in reducing calf muscle soreness. One hundred and sixty eight healthy individuals with a pain score ≥3 (10-point scale) 12–16 h post-exercise (walking down stairs with an altitude of 300–400 m) were randomised to receive IDEA-033 plus oral placebo (two dose groups), oral ketoprofen plus TDT 064, or TDT 064 plus oral placebo. The primary endpoint was muscle soreness reduction from pre-dosing to Day 7. Higher pain scores were recorded with oral ketoprofen plus TDT 064 (mean ± s 462.4 ± 160.4) versus IDEA-033 plus oral placebo (434.7 ± 190.8; P = 0.2931) or TDT 064 plus oral placebo (376.2 ± 159.1; P = 0.0240) in the 7 days post-exercise. Recovery from muscle soreness was longer with oral ketoprofen plus TDT 064 (mean 91.0 ± 19.5 h) versus IDEA-033 plus placebo (mean 81.4 ± 22.9 h; P = 0.5964) or TDT 064 plus placebo (mean 78.9 ± 22.8 h; P = 0.0262). In conclusion, ultradeformable phospholipid vesicles ± ketoprofen did not retard recovery from muscle soreness. TDT 064 improves osteoarthritis-related pain and could be of interest as a treatment for joint pain during and post-exercise.     

Electromyographic analysis of hip adductor muscles in soccer instep and side-foot kicking

ABSTRACT

A possible link between soccer-specific injuries, such as groin pain and the action of hip adductor muscles has been suggested. This study aimed to investigate neuromuscular activation of the adductor magnus (AM) and longus (AL) muscles during instep and side-foot soccer kicks. Eight university soccer players performed the two types of kick at 50%, 75% and 100% of the maximal ball speed. Surface electromyography (EMG) was recorded from the AM, AL, vastus lateralis (VL) and biceps femoris (BF) muscles of both kicking and supporting legs and the kicking motions were three-dimensionally captured. In the kicking leg, an increase in surface EMG with an increase in ball speed during instep kicking was noted in the AM muscle (p < 0.016), but not in AL, VL or BF muscles (p > 0.016). In the supporting leg, surface EMG of both AM and AL muscles was significantly increased with an increase in the ball speed before ball impact during both instep and side-foot kicks (p < 0.016). These results suggest that hip adductor muscles markedly contribute to either the kicking or supporting leg to emphasise the action of soccer kicks.     

青少年脊柱形态与功能对非特异性腰背疼痛的影响

摘要：目的：非特异性腰背疼痛已经成为影响青少年身体健康的公共卫生问题,脊柱形态与功能的改变可能是青少年非特异性腰背疼痛的影响因素。通过对青少年脊柱形态与功能的全面测试,可以为青少年非特异性疼痛的预防以及治疗提供可靠的依据。方法：对北京、天津地区四所中学进行问卷调查,筛选符合条件的受试者。在征得学生和家长同意的前提下,使用spinal mouse电子脊柱测量仪对非特异性腰背疼痛组273名（男,121名;女,152名）学生和对照组127名（男,63名;女,64名）学生进行脊柱形态与功能测试。测试指标包括直立位、坐位以及负重状态（Matthiass test）下的胸椎后凸角（TKA）、腰椎前凸角（LLA）、骶骨倾角(SA)、倾斜角(INA),以及前屈、后伸、左右侧屈时脊柱各节段活动度。计算TKA、LLA异常率（正常范围,TKA：20°～40°,LLA：24.6°～71.4°）,并使用似然比卡方检验比较不同年级组、不同性别、不同疼痛类型间的异常率。使用偏相关分析探讨非特异性腰背疼痛与年龄的相关性,使用二分类logistics回归模型对脊柱形态与功能等指标与非特异性腰背疼痛进行相关性分析。结果：1）初中生TKA异常率分别为47.0%,53.0%(男生、女生) ;高中生TKA异常率为52.6%,48.0% (男生、女生)。2）初中生LLA异常率为67.5%,45.2%（男生、女生）;高中生LLA异常率为52.6%和21.7%（男生、女生）。3）胸椎后凸角（P<0.05,OR=1.236）和腰椎从屈曲位到后伸位的活动度(P<0.01,OR=0.975)与青少年非特异性腰背疼痛具有相关性。结论： 本研究受试者中,胸椎后凸角与腰椎前凸角异常的比例较高。胸椎后凸角较大以及腰椎总体活动度不足是青少年发生非特异性腰背疼痛的危险因素。     

毫米波动物表面热效应研究

由于毫米波技术的发展,获得的较高功率的毫米波可直接作用于人体皮肤表面,产生强热刺痛,形成温度-疼痛生物效应。毫米波长时间辐照对动物的脑和眼睛均有影响和损伤。并论述了这种热效应的生化生理反应和相应的热物理模型。     

悲惨的一代,痛苦的缪斯--美国自白派诗歌现象述评

美国自白派诗人认为,有意义的经验是痛苦的经验,诗人必须痛苦才能深刻,痛苦是诗人个性和反思成熟的重要标志.痛苦给了自白派诗人生存最真切的体验和创作的灵感,同时也带给了他们毁灭性的灾难:以死来摆脱无法忍受的痛苦.     

Prevalence of shoulder pain in Swedish flatwater kayakers and its relation to range of motion and scapula stability of the shoulder joint

Few studies have investigated the incidence of injuries in kayakers. The aim was to study the prevalence of shoulder pain in competitive flatwater kayakers and to evaluate any differences in range of motion or scapula stability of the shoulder joint among kayakers with or without the history of shoulder pain. Thirty-one kayakers were participated in the study, and a questionnaire including background data was used. Shoulder range of motion was measured with a goniometer, and the participants were observed for scapula dyskinesis in flexion and abduction. Of the participating kayakers, 54.8% (n = 17) had experienced shoulder pain. Kayakers who had experienced shoulder pain showed a significantly lower degree of internal rotational range of motion versus kayakers with no reported shoulder pain, with a mean degree of internal rotation in the right shoulder 49.3 vs 60.0 (P = 0.017) and the left shoulder 51.9 vs 66.0 (P = 0.000). Kayakers who had experienced shoulder pain were also observed with a scapular dyskinesis (n = 15 of 17 kayakers) to a significantly higher degree (P = 0.001) than kayakers with no reported shoulder pain. Findings suggest that screening for scapular dyskinesis and testing for rotational range of motion in the shoulder joint is essential in order to treat and maybe prevent shoulder pain in kayakers.     

Exercise-related transient abdominal pain secondary to median arcuate ligament syndrome: a case report

Exercise-related transient abdominal pain is a common entity in young athletes. An uncommon aetiology of this type of pain is median arcuate ligament syndrome. This article details an 18-year-old field hockey player who presented with a 1-year history of exercise-related transient abdominal pain. Despite a trial of preventative strategies, the patient’s pain persisted, prompting surgical intervention. Following a laparoscopic median arcuate ligament release, the patient’s symptoms resolved. Therefore, when exercise-related transient abdominal pain persists despite precautionary measures, median arcuate ligament syndrome should be considered.     

瑜伽运动对慢性下腰痛中老年女性患者表面肌电信号的变化研究

目的：探讨瑜伽运动对慢性下腰痛中老年女性患者腰部肌肉功能的影响。方法：将40例慢性下腰痛中老年女性患者分为瑜伽组和对照组;对照组接受基础治疗,瑜伽组接受基础治疗的基础上进行12周的瑜伽练习,观察两组治疗前后左右竖脊肌、多裂肌的表面肌电信号的变化。结果：两组治疗后,均能提高直立位、俯卧位、前屈位、飞燕式的MF值（P＜0.05）,且瑜伽组显著大于对照组（P＜0.05）;两组均能降低直立位、俯卧位、前屈位、飞燕式的RMS值（P＜0.05）,且瑜伽组明显小于对照组（P＜0.05）。结论：进行瑜伽练习的基础治疗和单纯基础治疗均能提高腰部肌肉功能状态,降低腰部肌肉的疲劳程度,但进行瑜伽练习的基础治疗比单纯基础治疗效果更优。     

中药提取液离子电导入治疗顽固性腰腿痛42例临床观察

探讨腰腿痛治疗方法，运用中药提取液离子电导入治疗顽固性腰腿痛42例，疗效肯定，治愈率64．3％。总有效率95．3％．     

Exertional Heat Stroke of Max Gilpin; A Preventable Death

ABSTRACT

Exertional heat stroke (EHS) is a medical emergency whose likelihood in sport settings is often contingent on environmental factors, team policies, coaching strategies, and broader cultural expectations. Moreover, when it occurs, it requires immediate recognition, proper management, and care to optimize chances of survival or recovery without long-term sequelae. Max Gilpin, a secondary school American football player from Louisville, Kentucky, suffered an EHS during a football practice in August 2008, an event that resulted in his death. The purpose of this article is to use interdisciplinary methods to identify key factors that contributed to this tragedy so that similar situations do not happen again. It concludes that within a culture of inclusive gender norms and care, efforts should be made to have appropriate onsite medical expertise available to develop and implement best practices for the prevention, management, and treatment of EHS, along with coaching education specific to medical emergencies in sport and physical activity (such as EHS). This will create an environment that promotes health and safety for all student athletes participating in sport at the secondary school level.