Effect Mechanism of Structure-Changed Water on Heat Stability of Lysozyme

Theeffectofhydrationontheheatstabilityofbiologi calmacromolecules ,forexample ,lysozyme ,hasbeenstudiedbyanumberofresearchers.Thestudiesshowthattheheatstabilityoflysozymeisdirectlyrelatedtothehydrationamountandboundwateramountinlysozyme[1— 7] .Atthesametime ,differentialscanningcalorimetry(DSC)methodwasverifiedtobeaneffectivemethodforstudyingthestructureandheatsta bilityofbiologicalmacromolecules[8] .Inthiswork ,theeffectofmicrostructure changedwateronheatstabilityoflysozymeisstudiedbymeanso…     

提高文科高校学报质量的新思路

当前,文科高校学报质量低的突出表现是栏目雷同化和大杂烩化,没有能够体现本校学科优势和地域特色的个性化栏目,解决存在问题的途径有两条:一是实施专题化和特色化;二是建立高质量的稿源。     

匠心视域下的名匠特质探析

目的/意义:探讨名匠身上的匠心特质。方法/过程:以人格特质理论为基础,运用人物分析法对企业家、科学家、艺术家三个领域共30位名匠进行分析、概括、比较,总结得出匠心的特质。结果/结论:名匠匠心的共同特质有坚毅、敬业、精益求精、创新;科学家独有的特质是严谨、钻研、献身精神;企业家独有的特质是敢于冒险、洞察力;艺术家独有的特质是耐心、细心、专注;匠心是名匠身上具有的积极品质,要成为名匠,必须具备这些特质。     

工程教育专业认证背景下对高校热处理实验教学的若干思考

文章首先分析了我国热处理行业现状,与世界先进水平国家的差距及其原因,随后探讨了工程教育专业认证背景下,热处理实验教学在培养创新型复合人才方面的改革方向,最后指出了培养理论与实践相结合、企事业单位满意、自身价值成长的热处理专业人才的必要性和迫切性。     

传热强化方法

该文简要介绍了国内外常见的在单相流体与相变流体对流传热方面的强化方法及机理。     

热方程的三抛物面定理和解的唯一性

该文给出了关于超曲面族（x1^2…＋xn^2）／（t0-t）=p，满足△u-ut≥0的函数的三抛物面定理和热方程解的唯一性结果．     

稳态法测不良导体导热系数实验装置的改进

传统的稳态法测量不良导体的导热系数是用红外线灯泡当作热源，用热辐射的方式对被测样品进行加热，新改进的加热方式是用电熨斗当热源，采用接触的方式进行加热。实践证明：新改进的加热方式具有实验操作简单，测量的结果误差小，节省电能，降低成本等特点。     

Basic fibroblast growth factor alleviates brain injury following global ischemia reperfusion in rabbits

The aim of this study was to explore the protective effect of basic fibroblast growth factor (bFGF) on brain injury following global ischemia reperfusion and its mechanisms. Brain injury following global ischemia was induced by four vessels occlusion and systemic hypotension. Twenty-four rabbits were randomized into three groups: group A, only dissection of vessels; group B, intravenous infusion of normal saline after reperfusion for 6 h; group C, 30 μg/kg bFGF injected intravenously at the onset of reperfusion, then infused with 10 μg/(kg·h) for 6 h. Serum neuron specific enolase (NSE), S-100B, tumor necrosis factor-α(TNF-α), interleukin-1 (IL-1), interleukin-8 (IL-8) were measured before ischemia, 30 min after ischemia, 0.5, 1, 3, 6 h after reperfusion. Brain water content was determined and cerebral histopathological damages were compared. NSE and S-100B were increased 1 h after reperfusion and reached their peaks 6 h after reperfusion, but were much higher in group B than those in group C 3, 6 h after reperfusion. In groups B and C, TNF-a was increased after ischemia and IL-1 and IL-8 were increased significantly 0.5 h after reperfusion, then reached their peaks 6 h, 3 h, 6 h after reperfusion respectively. TNF-a and IL-8 at the time points of 1 h and 3 h and IL-1 at 3 h and 6 h in group C were correspondingly lower than those in group B. These indices in group A were nearly unchanged. There were less severe cerebral histopathological damages in group C compared with group B, but no difference in brain water content. It could be concluded that bFGF alleviates brain injury following global ischemia and reperfusion by down-regulating expression of inflammatory factors and inhibiting their activities.     

模具热处理中失效变形的原因及其对策

模具热处理技术是确保模具质量、延长使用寿命的关键所在，本文试就模具热处理过程中常遇到的失效变形等问题进行分析并作出相应对策。     

Intrathymic inoculation of donor liver specific antigen alleviates rejection of liver allotransplantation

Use and effects of liver specific antigen in orthotopic liver transplantations were researched in this study. Group I: syngeneic control (Wistar-to-Wistar); Group II: acute rejection (SD-to-Wistar); Group III: Thymic inoculation of SD rat LSA day 7 before transplantation. The observation of common situation and survival time, rejection grades, NF-κB activity of splenocytes and IL-2mRNA expression of grafted liver were used to analyze acute rejection severity and immune state of animals in different groups. The common situation of group I was very well after transplantation and no signs of rejection were found. Recipients of group II lost body weight progressively All dead within day 9 to day 13 posttransplantation; median survival time was 10.7 ±0.51 days. It was an optimal acute rejection control. As for group III, 5 out of 6 recipients survived for a long time and common situation was remarkably better than that of group II. Its rejection grades were significantly lower than that of group II(P<0.05). NF-κB activity was only detected in group I at day 5 and day 7 after transplantation, whereas high activity of NF-κB was detected at all time points in groupII and the low NF-κB activity detected in group III was significantly lower than that of group II (P<0.05). No IL-2mRNA expression was detected at any time point in group I, whereas high level expression was detected at all time points in group II and the low level expression only detected at day 3 in group III was significantly lower than that of group II (P<0.05). Conclusion: LSA is an important transplantation antigen which is involved directly in the immunorejection of liver transplantation. We report here for the first time that intrathymic inoculation of LSA can alleviate the rejection of liver allotransplantation; and that grafts can survive for a long time thereby, thus leading to a novel way to achieve liver transplantation immunotolerance. Project (NO. 011106206) supported by the Science and Technology Bureau of Zhejiang Province Foundation