Notable and Emerging Variants of SARS-CoV-2 Virus: A Quick Glance

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the etiological agent of coronavirus disease-2019 (COVID-19), is a highly contagious pathogenic coronavirus to emerge and spread in human populations. Although substantial exertions have been laid to avert spread of COVID-19 by therapeutic and preventive countermeasures, but emergence of SARS-CoV-2 variants as a result of mutations make the infection more ominous. New viral confers a higher nasopharyngeal viral load, increased viral transmissibility, higher infectiousness, immune escape, increased resistance to monoclonal/polyclonal antibodies from convalescence sera/vaccine, and an enhanced virulence. Thus, it is pertinent to monitor evolving mutations and genetic diversity of SARS-CoV-2 as it is decisive for understanding the viral variants. In this review we provide an overview of colloquial nomenclature and the genetic characteristics of different SARS-CoV-2 variants in the context of mutational changes of the circulating strains, transmissibility potential, virulence and infectivity.     

介词多义现象的认知理据

本文通过对介词进行分析，探讨多义现象的认知理据意象图式的认知机制，分析了中心图式与变体图式对空间域多义的影响以及意象图式的隐喻扩展对抽象域多义的影响。     

论科技英语的文体特征

科技英语是科技工作者用英语交流某一科技领域内的研究成果,传递现代信息的一种交通工具,是英语的一种功能变体。本文主要探讨科技英语的主要文体特征。     

惠州方言古语词及其用字问题略论

惠州方言词汇中保存了大量的古语词,研究这些古语词对于训诂研究有着不可忽视的价值。惠州方言古语词研究在用字上主要存在两个方面的问题：一是随意使用异体俗字;二是滥用同音字。     

溧水“街上话”声母变异分析

文章运用社会语言学的研究方法,对溧水”街上话”声母变异情况进行调查与分析。分析得出：声母变异具有社会分布特征、阶段性特征和方向性特征;变异一方面受到原系统的制约,另一方面又改变了原有声韵组合规律,出现了声母的归并、腭化和调整,打破了原有声母系统。     

哈尼亲属称谓语泛化初探

正如现代汉语中有亲属称谓泛化现象一样,哈尼语称谓系统中也存在亲属称谓泛化现象,但尚未有人作过专门研究,本文将描述哈尼亲属称谓泛化的方式,分析泛化的特点,着重从社会经济结构,民族心理,礼貌原则,以及亲属称谓借用探讨其泛化的原因。     

Deletions in the genomes of fifteen inbred mouse lines and their possible implications for fat accumulation

Copy number variants (CNVs) are pieces of genomic DNA of 1000 base pairs or longer which occur in a given genome at a different frequency than in a reference genome. Their importance as a source for phenotypic variability has been recognized only in the last couple of years. Chromosomal deletions can be seen as a special case of CNVs where stretches of DNA are missing in certain lines when compared to the reference genome of the mouse line C57BL/6, for example. Based upon more than 8 million single nucleotide polymorphisms (SNPs) in the fifteen inbred mouse lines which were determined in a whole genome chip based resequencing project by Perlegen Sciences, we detected 20166 such long chromosomal deletions. They cover altogether between 4.4 million and 8.8 million base pairs, depending on the mouse line. Thus, their extent is comparable to that of SNPs. The chromosomal deletions were found by searching for clusters of missing values in the genotyping data by applying bioinformatics and biostatistical methods. In contrast to isolated missing values, clusters are likely the consequence of missing DNA probe rather than of a failed hybridization or deficient oligos. We analyzed these deletion sites in various ways. Twenty-two percent of these deletion sites overlap with exons; they could therefore affect a gene's functioning. The corresponding genes seem to exist in alternative forms, a phenomenon that reminds of the alternative forms of mRNA generated during gene splicing. We furthermore detected statistically significant association between hundreds of deletion sites and fat weight at the age of eight weeks.     

宋本《玉篇》形声结构异体字义符换用考

宋本《玉篇》中形声结构异体字换用义符是有理据的,缘于造字时代人们的思维方式与生产、生活条件的有机结合。换用方式有三种:一是不同造字角度下的换用;二是同一造字角度下的相似换用,包括义符义近换用、义符所指事物的部分属性相同而换用两类;三是同一造字角度下的相关换用,包括义符所指事物客观上有联系而换用、人们主观上认为某些义符所指事物有联系而换用、以个别代一般三类。     

基于COCA语料库英语谚语变体模式分析

本文借助于美国当代英语语料库（COCA）的真实语料,通过对《美国谚语101则》中的谚语分析归类,研究探讨不同类型结构的英语谚语的变体现象。研究发现,不同类型的英语谚语的变体有不同的倾向;总的来说,英语谚语的变体模式有时态变化,替换,简化,扩犀,反义等几种主要的形式。     

A multilevel meta-analysis of studies reporting correlations between the h index and 37 different h index variants

This paper presents the first meta-analysis of studies that computed correlations between the h index and variants of the h index (such as the g index; in total 37 different variants) that have been proposed and discussed in the literature. A high correlation between the h index and its variants would indicate that the h index variants hardly provide added information to the h index. This meta-analysis included 135 correlation coefficients from 32 studies. The studies were based on a total sample size of N = 9005; on average, each study had a sample size of n = 257. The results of a three-level cross-classified mixed-effects meta-analysis show a high correlation between the h index and its variants: Depending on the model, the mean correlation coefficient varies between .8 and .9. This means that there is redundancy between most of the h index variants and the h index. There is a statistically significant study-to-study variation of the correlation coefficients in the information they yield. The lowest correlation coefficients with the h index are found for the h index variants MII and m index. Hence, these h index variants make a non-redundant contribution to the h index.