本科生导师制的实践与思索 ——以医学影像技术专业为例

为响应国家加快建设高水平本科教育,全面提高人才培养能力的号召,院系探索实施了三届的本科生导师制教学.本科生导师制是对传统本科教育模式的补充,让师生之间的沟通更为紧密,为培养高素质人才提供了一种新的途径,在大部分本科生中反响较好.但在实施本科生导师制的过程中也遇到了一些问题,文章对本科生导师制教学实践做了总结和思考,分析...     

心理成长论本——超越心理发展的心理学主张

心理成长的概念是对心理发展的概念的超越。发展心理学提供了关于人的心理发展的学说,但发展心理学的研究一直存在着重要的缺失。用心理成长概念去替代心理发展概念应该成为考察人的心理行为的一个重要的理论转换,新心性心理学则实现了这一重大的研究范式的转换。这种范式转换包括:将着重于生物和生理转向着重于心理和心性,将着重于成熟和发展转向着重于成长和提升,将强调心理的直线发展转向全面扩展,将强调心理的平面扩展转向纵向提升。心理成长不是孤立的,它与心理资源、心理文化、心理生活、心理环境和心理生成有着重要的关联。人的存在、人的生活、人的心理、人的成长等,可以按照个体、群体、民族、社会、文化这五种方式来考察。     

高校学生中开展俱乐部式教学的优势研究

通过文献资料法和归纳演绎法等，对高校试行的俱乐部式教学进行研究。从终身体育的视角阐述了在高校高年级学生中建立体育俱乐部的必要性和可行性及优势，提出建立体育俱乐部的理论依据和办法.使体育俱乐部活动逐渐成为课堂教学的延伸与发展，为丰富学校体育现代化的内容和寻求改革创新教学模式的院校提供借鉴。     

Binding interactions of pefloxacin mesylate with bovine lactoferrin and human serum albumin

The binding of pefloxacin mesylate （PFLX） to bovine lactoferrin （BLf） and human serum albumin （HSA） in dilute aqueous solution was studied using fluorescence spectra and absorbance spectra. The binding constant K and the binding sites n were obtained by fluorescence quenching method. The binding distance r and energy-transfer efficiency E between pefloxacin mesylate and bovine lactoferrin as well as human serum albumin were also obtained according to the mechanism of Forster-type dipole-dipole nonradiative energy-transfer. The effects of pefloxacin mesylate on the conformations of bovine lactoferrin and human serum albumin were also analyzed using synchronous fluorescence spectroscopy.     

开辟医学影像学期刊品牌专栏"图文讲座"

探讨创办医学影像学期刊"图文讲座"新栏目的经验.认为以图文讲座为品牌栏目,不仅适应了"读图时代"受众心理和阅读取向,而且显示了该类专业杂志的突出特色,有利于期刊国际化的交流,提升了核心竞争力.     

地遥江汉 心志鹧鸪——龚鼎孳山水诗简论

清初＂江左三大家＂命运趋同,诗风各异,龚鼎孳作为三大家的殿军,虽人格亏缺,但诗风清丽婉转,有其独到之处。他的主要以粤赣风物为描写对象的山水诗,写景细腻,用词精准,诗风清奇峭厉、幽深奥妙,给人以强烈的视觉冲击力,在三大家的山水诗中,因其题材醒目、诗风矫健而独占鳌头。探讨龚鼎孳的山水诗,有助于我们从更深层面把握诗人在特殊时代背景下生成的人格特质。     

金属化合物对LDPE／IFR体系热降解行为的影响

以多聚磷酸铵（APP）与自制齐聚物式成炭剂（OCA）复配成新型膨胀型阻燃剂（IFR）,采用热重分析仪（TGA）研究硼酸锌（ZB）和二氧化锰（MnO2）对LDPE／IFR体系热降解行为的影响。结果表明,氮气气氛下,金属化合物都能促使复合材料形成更多的残炭,但对热降解活化能的影响不明显;空气气氛下,MnO2可减缓材料的初始降解,使复合材料寿命延长,而ZB则使复合材料初始降解延长,寿命缩短。     

钝顶螺旋藻藻胆体在解离过程中液氮(77K)荧光发射光谱与光能传递的研究

对钝顶螺旋藻藻胆体在解离过程中77K荧光发射光谱与光能传递途径进行了研究.在77K荧光发射光谱中,完整藻胆体只有一个峰,位于682nm,这是藻胆体核心-类囊体膜连接多肽的荧光峰;随着藻胆体逐渐解离,首先在649nm出现一个小峰,之后,在661nm又出现一个荧光发射肩,前者是C-藻蓝蛋白的荧光,后者是别藻蓝蛋白的荧光;随着藻胆体解离程度的加重,C-藻蓝蛋白的荧光逐渐加强并成为主峰,别藻蓝蛋白的荧光也逐渐加强,但随后又逐渐减弱,直至消失;682nm主峰逐渐减弱并消失,但在679nm却出现另一个荧光峰,这是别藻蓝蛋白-B的荧光;当别藻蓝蛋白的荧光消失后,679nm荧光峰减弱为荧光发射肩,但仍然有很强的荧光.这表明:C-藻蓝蛋白不但与别藻蓝蛋白相连接,而且还与别藻蓝蛋白-B相连,在钝顶螺旋藻藻胆体中,光能是沿着两条途径传递给光系统Ⅱ的.     

Three-dimensional tracking of GLUT4 vesicles in TIRF microscopy

TIRF microscopy has provided a means to view mobile granules within 100 nm in size in two dimensions. However quantitative analysis of the position and motion of those granules requires an appropriate tracking method. In this paper, we present a new tracking algorithm combined with the unique features of TIRF. Firstly a fluorescence correction procedure was processed to solve the problem of fluorescence bleaching over time. Mobile granules were then segmented from a time-lapse image stack by an adaptive background subtraction method. Kalman filter was introduced to estimate and track the granules that allowed reducing searching range and hence greater reliability in tracking process. After the tracked granules were located in x-y plane, the z-position was indirectly inferred from the changes in their intensities. In the experiments the algorithm was applied in tracking GLUT4 vesicles in living adipose cells. The results indicate that the algorithm has achieved robust estimation and tracking of the vesicles in three dimensions.     

Cinematic Rendering in Anatomy: A Crossover Study Comparing a Novel 3D Reconstruction Technique to Conventional Computed Tomography

Integration of medical imaging into preclinical anatomy courses is already underway in many medical schools. However, interpretation of two-dimensional grayscale images is difficult and conventional volume rendering techniques provide only images of limited quality. In this regard, a more photorealistic visualization provided by Cinematic Rendering (CR) may be more suitable for anatomical education. A randomized, two-period crossover study was conducted from July to December 2018, at the University Hospital of Erlangen, Germany to compare CR and conventional computed tomography (CT) imaging for speed and comprehension of anatomy. Sixteen students were randomized into two assessment sequences. During each assessment period, participants had to answer 15 anatomy-related questions that were divided into three categories: parenchymal, musculoskeletal, and vascular anatomy. After a washout period of 14 days, assessments were crossed over to the respective second reconstruction technique. The mean interperiod differences for the time to answer differed significantly between the CR–CT sequence (−204.21 ± 156.0 seconds) and the CT–CR sequence (243.33 ± 113.83 seconds; P < 0.001). Overall time reduction by CR was 65.56%. Cinematic Rendering visualization of musculoskeletal and vascular anatomy was higher rated compared to CT visualization (P < 0.001 and P = 0.003), whereas CT visualization of parenchymal anatomy received a higher scoring than CR visualization (P < 0.001). No carryover effects were observed. A questionnaire revealed that students consider CR to be beneficial for medical education. These results suggest that CR has a potential to enhance knowledge acquisition and transfer from medical imaging data in medical education.