创业理论:多元的研究视角

作为一个新兴的研究领域,创业理论研究视角呈现出了多元的特点。对目前创业理论研究的不同分析视角进行梳理,可以概括描述各种主要分析视角的创业理论观点。随着研究的深入,创业理论将有更多的分析视角,其研究也将在较长时期内维持多元化的发展特点。     

On-line estimation of concentration parameters in fermentation processes

INTRODUCTION Saccharomycete, closely linked with human life, is the only microbe that has been utilized to the extent of over a million tons in the world, and is one of the modelled biological bacteria mostly used in modern genetic engineering. Since there are no effective online instruments for measuring the production or resultant concentration, which is a very important quality index in fermentation process, soft sensors (Martin, 1997; Tham et al., 1991; Assis and Filho, 2000; Salgad…     

论图书馆管理

本文论述了图书馆管理的一条方针、二项任务、三个目标、四种作风，是笔者管理实践的总结。     

A case of IgA multiple myeloma: Nutritional perspective in diagnostic testing

A 64-year-old security guard and longstanding known hypertensive presented with hypertensive heart disease (HHD), weight loss, an enlarged prostate, and a spontaneously fractured rib. Malignancy of the prostate with possible metastases to the ribs was strongly suspected. Biochemical profiling revealed a paraprotein. Other biochemical and hematological correlates that were on hand before serum protein electrophoresis were rather atypical. Paraprotein studies by immunofixation revealed IgA myelomatosis. Unlike previous reports from Caucasians there was normocalcaemia, normal protein level, microcytic hypochromia, low MCHC, cholesterol level at the lower limit of the reference range and normal urea level (in the face of markedly raised creatinine level). Nutritional modulation of the classical laboratory features of this disease may account for the fairly atypical laboratory picture. The need to appreciate the influence of nutritional status on the laboratory (especially biochemical) features of a disease and thus interpretation of diagnostic tests appears of exceptional current importance, given the widening gap in socioeconomic status and the level of poverty between the resource poor and developed countries from which the classical, clinical and laboratory features of most diseases were first described. This case report reminds of the need not only to recognize theoretically the impact of nutritional status on the laboratory characteristics of a disease but of the practical application of the nutritional perspective in the interpretation of diagnostic investigations, especially in nutritionally disadvantaged communities.     

A hybrid generative/discriminative approach to text classification with additional information

This paper presents a classifier for text data samples consisting of main text and additional components, such as Web pages and technical papers. We focus on multiclass and single-labeled text classification problems and design the classifier based on a hybrid composed of probabilistic generative and discriminative approaches. Our formulation considers individual component generative models and constructs the classifier by combining these trained models based on the maximum entropy principle. We use naive Bayes models as the component generative models for the main text and additional components such as titles, links, and authors, so that we can apply our formulation to document and Web page classification problems. Our experimental results for four test collections confirmed that our hybrid approach effectively combined main text and additional components and thus improved classification performance.     

Students’ effort allocation to their perceived strengths and weaknesses: The moderating effect of instructional strategy

To become competent professionals, students should work on both their strengths and weaknesses. Considering students' limited amount of time and energy to work on multiple subjects, it is important to know what determines their allocation of effort to their perceived relative strengths or weaknesses. In a series of five studies, we examined the moderating effect of instructional strategy (i.e., self-directed versus test-directed) on the within-person relation between perceived relative strength (i.e., strengths versus weaknesses) and allocated effort across multiple subjects. We used different methodologies (scenario, field, and experimental studies), research designs (within-person and mixed factorial), populations (secondary school, college, and university students), and measures of effort (intentions, self-reported, and behavioral). The results consistently indicate that students in a self-directed instructional strategy condition tend to allocate more effort to their relative strengths, whereas students in a test-directed instructional strategy condition tend to allocate more effort to their relative weaknesses.     

基于网络的多元形成性评价研究

形成性评价是开放教育教学过程质量控制的一个重要途径。从开放教育课程学习目标,即知识性学习目标、学习能力目标和情感性目标出发,构建了多元形成性评价指标体系、管理运行机制及系统架构。并根据多元形成性评价系统架构,设计了题库和作业库结构,提出了基于六维约束的自动组卷算法。针对真实数据集进行的大量实验表明,该算法具有较高的效率,从而为多元形成性评价系统的成功应用奠定了基础。随着互联网的飞速发展,社会性评价、发展性评价以及个性化、智能化评价将是形成性评价的发展方向。     

Leveraging microgrants to support capacity-building workshops in low- and middle-income countries for meeting the Sustainable Development Goals

Twenty fifteen marked the year of assessment for the Millennium Development Goals (MDGs). The MDGs that achieved the greatest success were those where evidence-based practice (EBP) interventions were implemented. The ability to practice evidence-based medicine is grounded in the creation of and access to medical literature that synthesizes research findings. The role that global health literature played in the success of the MDGs demonstrates that medical libraries and librarians have a role to play in achieving the Sustainable Development Goals (SDGs).Librarians can hold capacity-building workshops that provide instruction on how to access evidence-based literature and also train health professionals to conduct synthesis research. Research findings conducted by in-country health professionals are more likely to address issues being faced by local communities and will afford the possibility of obtaining the necessary evidence-based answers that can then be used to implement policies to resolve public health issues identified in the SDGs.This paper discusses how an international team of librarians leveraged funding from a Medical Library Association/Librarians without Borders/Elsevier Foundation/Research4Life grant to hold a capacity-building workshop in Zimbabwe and follow-up online trainings. The workshop focused on accessing evidence-based resources and conducting synthesis research. Outcomes included the creation and policy implementation of evidence-based knowledge products in alignment with local needs and galvanizing a multisectoral group of key individuals who have gone on to collaborate toward the vision of creating a Zimbabwe innovation hub. Looking ahead, such grants can be leveraged to conduct capacity-building to support knowledge translation and other local training needs.     

Application of network meta-analysis in the field of physical activity and health promotion

Continued advancement in the field of physical activity and health promotion relies heavily on the synthesis of rigorous scientific evidence. As such, systematic reviews and meta-analyses of randomized controlled trials have led to a better understanding of which intervention strategies are superior (i.e., produce the greatest effects) in physical activity-based health behavior change interventions. Indeed, standard meta-analytic approaches have allowed researchers in the field to synthesize relevant experimental evidence using pairwise procedures that produce reliable estimates of the homogeneity, magnitude, and potential biases in the observed effects. However, pairwise meta-analytic procedures are only capable to discerning differences in effects between a select intervention strategy and a select comparison or control condition. In order to maximize the impact of physical activity interventions on health-related outcomes, it is necessary to establish evidence concerning the comparative efficacy of all relevant physical activity intervention strategies. The development of network meta-analysis (NMA)—most commonly used in medical-based clinical trials—has allowed for the quantification of indirect comparisons, even in the absence of direct, head-to-head trials. Thus, it stands to reason that NMA can be applied in physical activity and health promotion research to identify the best intervention strategies. Given that this analysis technique is novel and largely unexplored in the field of physical activity and health promotion, care must be taken in its application to ensure reliable estimates and discernment of the effect sizes among interventions. Therefore, the purpose of this review is to comment on the potential application and importance of NMA in the field of physical activity and health promotion, describe how to properly and effectively apply this technique, and suggest important considerations for its appropriate application in this field. In this paper, overviews of the foundations of NMA and commonly used approaches for conducting NMA are provided, followed by assumptions related to NMA, opportunities and challenges in NMA, and a step-by-step example of developing and conducting an NMA.     

Modeling Interactional Influence in Advice Exchanges: Advice Giver Goals and Recipient Evaluations

This study examined how advice givers' self-reported interaction goals influence recipients' evaluations of advice. A typology of giver goals was developed based on message production theories, and the influence of goal pursuit on evaluations of advice was analyzed in interactions between friends (N=189 dyads). In the structural equation model, several giver goals directly affected recipients' evaluations of specific advice features (e.g., greater effort to give efficacious and feasible advice resulted in ratings of advice as more efficacious and feasible). In turn, recipient evaluations of specific message features influenced their ratings of advice message quality. Advice giver goals of efficacy/feasibility, politeness, and novelty led to positive recipient ratings, whereas effort to change the recipient's mind led to negative evaluations.