论教育评价理论与实践的基本走向

当前,有关教育评价理论与实践的概念逻辑性不强,并且有些概念的提法有失偏颇,针对此种现象,本文从教育理论的特点出发,在此基础上,着重探讨教育评价各组成部分在这些理论的影响下的基本走向。     

Cooperative co-evolution based distributed path planning of multiple mobile robots

This paper proposes novel multiple-mobile-robot collision avoidance path planning based on cooperative co-evolution, which can be executed fully distributed and in parallel. A real valued co-evolutionary algorithm is developed to coordinate the movement of multiple robots in 2D world, avoiding C-space or grid net searching. The collision avoidance is achieved by cooperatively co-evolving segments of paths and the time interval to pass them. Methods for constraint handling, which are developed for evolutionary algorithm, make the path planning easier. The effectiveness of the algorithm is demonstrated on a number of 2D path planning problems.     

The pedagogical potential of drawing and writing in a primary science multimodal unit

In consideration of the potential of drawing and writing as assessment and learning tools, we explored how early primary students used these modes to communicate their science understandings. The context for this study was a curricular unit that incorporated multiple modes of representation in both the presentation of information and production of student understanding with a focus on the structure and function of carnivorous plants (CPs). Two science teacher educators and two first-grade teachers in the United States co-planned and co-taught a multimodal science unit on CP structure and function that included multiple representations of Venus flytraps (VFTs): physical specimens, photographs, videos, text, and discussions. Pre- and post-assessment student drawings and writings were statistically compared to note significant changes, and pre- and post-assessment writings were qualitatively analysed to note themes in student ideas. Results indicate that students increased their knowledge of VFT structure and function and synthesised information from multiple modes. While students included more structures of the VFT in their drawings, they were better able to describe the functions of structures in their writings. These results suggest the benefits for student learning and assessment of having early primary students represent their science understandings in multiple modes.     

辐角函数的研究

利用集合来定义辐角函数，研究幅角函数的存在性、连续性、可微性等性质。     

多元智力理论中隐含的"智慧"观--中国古代智力观和多元智力理论的比较

加德纳的多元智力理论是一种教育哲学思想,这种哲学思想不仅试图解释“智力”的结构,而且还包含了“智慧”观念.西方传统智力理论“简洁”结构的主核是语言和数理能力,加德纳拓展了智力的内涵,使其更接近“智慧”的概念,这与中国传统智力观有许多呼应之处.     

潜藏在水下的冰山——《终成眷属》中的召唤结构

《终成眷属》的表层存在“爱情与偏见”的冲突。但从结构、情感两个层面分析后，我们可以从表层的冲突中发现伊瑟尔的“召唤结构”，这给我们提供了另一种审美空间，有助于更好地理解作品的主题。     

To Read or Not to Read: A Qualitative Study of Students’ Justifications for Document Selection in Task-Oriented Reading

When navigating through the vast amount of information that we encounter in our everyday lives, we constantly make decisions concerning what information to read more closely and what information to disregard. Consideration of the relevance and trustworthiness of information sources facilitates those decisions. In the present study, we interviewed 25 upper-secondary students after they had selected documents to use in completing a task, and we asked them to justify their selections. A qualitative analysis of the interview data showed that students’ justifications could be related to (1) content relevance, (2) source features, and (3) prior topic knowledge. The results demonstrate that students are able to evaluate content relevance and source features as part of their document selection strategies but that perceived prior knowledge seems to influence both selections and justifications.     

嵌合抗原受体T细胞在治疗难治/复发多发性骨髓瘤中的新进展（英文）

多发性骨髓瘤被认为是一种无法治愈的血液系统恶性疾病,其特征为恶性浆细胞的克隆性增殖。尽管在过去的几十年中,自体干细胞移植(ASCT)的应用及新型药物(蛋白酶体抑制剂和免疫调节药)的问世,将患者的中位生存时间由原来的4年提高到了8年,但复发与难治仍然是多发性骨髓瘤疾病进程中难以逾越的鸿沟。为了获得长期持续的缓解,免疫治疗开始在多发性骨髓瘤中崭露头角,其中嵌合抗原受体(CAR)T细胞治疗就是最有潜力的一颗新星。通过在基因层面改造患者自己的T细胞,使T细胞表达一种特定的受体(人造的融合蛋白),该受体可以识别并结合肿瘤相关抗原,并活化T细胞启动后续的杀伤过程。Tisagenlecleucel和Axicabtagene是两个针对CD19抗原的CAR T产品,用于治疗B细胞来源的急性淋巴细胞白血病(B-ALL)和弥漫大B细胞淋巴瘤(DLBCL),并于2017年被美国食品药品监督管理局(FDA)批准。这两个产品的发展极大推动了B细胞来源的恶性血液系统疾病的治疗,并刷新了对于传统治疗的认知。基于之前CAR T治疗的成功经验,寻找如CD19一样的特定靶点能为CAR T治疗多发性骨髓瘤打下基础。本综述介绍了数个在骨髓瘤细胞上的肿瘤靶抗原,如B细胞成熟抗原(BCMA)和CD38。这些针对抗原的CAR T治疗有些还在实验室阶段,而有些已经进入了3期的临床试验,很有可能成为下一个被批准的CAR T产品。另外,本综述也介绍了在CAR T治疗中出现的毒副反应以及相应的管理和处理方法。     

Context effects and the processing of spoken homophones

This study examined the role of context effects in the processing of homophones in Chinese and Chinese-English bilingual speech. In Experiment 1, Chinese speakers were presented with successively gated portions of a homophone in a sentence context, and they identified the homophone on the basis of its increasing acoustic information. In Experiment 2, Chinese-English bilinguals were presented with a cross-language homophone in a sentence context, and they named a visual probe that had or did not have phonological overlaps with the homophone. Results indicate that prior sentence context has an early effect on the disambiguation of various homophone meanings, shortly after the acoustic onset of the word, in both monolingual and bilingual situations. The results are accounted for by interactive activation models of lexical processing, in which the recognition of a homophone is a result of the interactions among phonological, lexical, and contextual information at an early stage.     

多元主体需求下的专利预警研究回顾与展望

以现有专利预警相关文献为研究对象,通过系统回顾与深度分析,对多元主体需求下的专利预警研究现状进行总结与梳理,分析其主要特征,并提出促进专利预警研究创新发展的改进思路与方向.研究发现:目前针对专利预警的概念内涵主要围绕专利威胁态势、专利竞争风险和专利侵权纠纷等视角展开探讨,关于专利预警机制建立的必要性、基本原则、关键作用...