重塑民办高等教育评估观

评估是有效规范和促进民办高校发展的一种手段。当前要做好民办高等教育的评估工作,除了科学的评估指标体系、数据的有效获取、权威评估专家等条件外,还需要我们在观念上的与时俱进。     

基质金属蛋白酶与冠心病

冠心病的病理学基础是动脉粥样硬化.目前认为动脉粥样硬化的形成和斑块的破裂与细胞外基质的破坏和重构有密切关系,而基质金属蛋白酶(MMPs)是降解细胞外基质的重要酶类.对近年来关于MMPs的结构、功能、基因表达以及在冠心病中的作用的研究取得的成果进行了综述.     

LONG-TERM INHIBITION OF Na~ /H~ EXCHANGE ATTENUATES CARDIAC REMODELING AFTER MYOCARDIAL INFARCTION IN RATS

ＩＮＴＲＯＤＵＣＴＩＯＮＴｈｅＮａ /Ｈ ｅｘｃｈａｎｇｅｒ (ＮＨＥ)ｉｓａｐＨ ｒｅｇｕｌａｔｏｒｙｐｒｏｔｅｉｎｐｒｅｓｅｎｔｉｎｔｈｅｐｌａｓｍａｍｅｍ ｂｒａｎｃｅｏｆｃａｒｄｉｏｍｙｏｃｙｔｅｓａｎｄｏｔｈｅｒｃｅｌｌｔｙｐｅｓ.ＡｌｔｈｏｕｇｈｓｅｖｅｒａｌｉｓｏｆｏｒｍｓｏｆＮＨＥｈａｖｅｂｅｅｎｄｅ ｃｒｉｂｅｄ,ｔｈｅｐｒｅｄｏｍｉｎａｎｔｉｓｏｆｏｒｍｉｎｔｈｅｈｅａｒｔｉｓｔｈｅｕｂｉｑｕｉｔｏｕｓＮＨＥ 1 ,ｗｈｉｃｈｕｎｄｅｒｃｅｎｔａｉｎｐｈｙｓｉｏｌｏｇｉｃａｌｃｏｎｄｉｔｉ…     

走向重塑:教育信息化的本土化景观演变

随着全球教育不断深入发展,"技术促变教育"的呼声逐渐演变成各国抢占教育信息化的制高点、提升国家综合实力的实施战略。承袭联合国教科文组织的规划,各国教育信息化发展基本沿着"起步—应用—融合—创新"的脉络发展,同时由于各国的基本国情不同而呈现出差异化的特色,这些特色成为各国教育信息化本土化发展的独有特质与形态。纵观国际社会,教育信息化已经走向了重塑教育生态的阶段。我国要实现"教育变革"的目标,必然要快速响应"重塑"阶段的诉求,处理好公平与均衡的诉求博弈、素养的全面发展目标落实以及改革执行力的自生长的快速形成等社会文化层面的问题。对此,我国已经进行了卓有成效的探索,积极推动了我国教育信息化的本土化进程。     

唤起对敬畏意识的重新礼赞

敬畏之含义是不可分割的。敬畏是一种美德,而无所畏惧常常是破坏的根源,是社会发展和进步的灾难。当代中国人应该重塑敬畏意识,尽快形成对法律、规章制度、道德规范等的敬畏之心。其形成、发展、定型和完善,需要借助于对中国传统的敬畏意识的继承,而这个继承维护的是社会的良性运行。     

学校生活中教师权威的退隐及其重塑

随着信息技术和网络文化的发展、构建新型师生关系的诉求以及教学模式的"程序化"使用等,教师传统的知识权威、角色权威和感召权威呈现出退隐形态。但在学校生活实践场域,学生的年龄特征和成熟度呼唤教师的智慧权威;师生关系民主化要求重新解读教师的角色权威;课堂教学的深度变革需要教师继续发挥感召权威。这些赋予了教师权威存在的合理性价值。鉴于此,拟尝试通过"外发型"法理性权威与"内生型"专业性权威这两种路径来实现教师合理性权威的重塑。     

浅谈食品营养与卫生课程重塑

更新教学理念、转变教学模式已逐渐成为广大教师的共识。探索一种新型的、能够体现学生学习主动性的教学方法已成为一线教师努力的方向。通过食品营养与卫生课程重塑,总结在重塑过程中应重点关注的几个方面。     

Metabolic remodeling in chronic heart failure

Although the management of chronic heart failure (CHF) has made enormous progress over the past decades, CHF is still a tremendous medical and societal burden. Metabolic remodeling might play a crucial role in the pathophysiology of CHF. The characteristics and mechanisms of metabolic remodeling remained unclear, and the main hypothesis might include the changes in the availability of metabolic substrate and the decline of metabolic capability. In the early phases of the disease, metabolism shifts toward carbohydrate utilization from fatty acids (FAs) oxidation. Along with the progress of the disease, the increasing level of the hyperadrenergic state and insulin resistance cause the changes that shift back to a greater FA uptake and oxidation. In addition, a growing body of experimental and clinical evidence suggests that the improvement in the metabolic capability is likely to be more significant than the selection of the substrate.     

A Library Staff Becomes a Team

Abstract

The staff of the Management & Economics Library of the Krannert Graduate School of Management at Purdue University used group problem solving techniques developed by The Institute of Cultural Affairs (ICA) to redesign the floor plan of the circulation, periodicals, and reference areas of the library to best utilize the space. The ToP^tm (Technology of Participation) planning process utilizes visualizing, brainstorming, and clustering of ideas. Its planning process consists of five workshops: mapping out the practical vision; analyzing the underlying contradictions; setting the strategic directions; designing the systematic action plan; and drawing up the implementation timeline. Each of these workshops is described in part one of this article. Part two describes the implementation of the changes and includes a list of changes, their associated costs, and goals they accomplished. The appendix includes before and after floor plans     

Growth factors induce the improved cardiac remodeling in autologous mesenchymal stem cell-implanted failing rat hearts

Therapeutically delivered mesenchymal stem cells (MSCs) improve ventricular remodeling. However,the mechanism underlying MSC cardiac remodeling has not been clearly determined. Congestive heart failure (CHF) was induced in rats by cauterization of the left ventricular free wall. MSCs were cultured from autologous bone marrow and injected into the border zone and the remote myocardium 5 d after injury. Ten weeks later,when compared with sham operation,CHF significantly increased nucleus mitotic index,capilla...