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This study investigated patterns of Bannatyne's recategorized WISC-R scores of 146 predominantly Tlingit Indian children who were referred for psychoeducational testing. The students were divided into two groups, ages 6 through 10 and 11 through 16, in order to investigate patterns that occurred at each level and to investigate the proportions that exhibited a typically “Indian” pattern: Spatial > Sequential > Conceptual and Acquired Knowledge. As a group, the older children displayed an Indian pattern, but the younger children displayed a different one: Spatial > Conceptual and Sequential > Acquired Knowledge. Both groups, however, displayed a significantly greater proportion of children with an Indian pattern than would be expected by chance. A considerable number of individuals from both groups attained significant differences among scores in the Indian direction.  相似文献   
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Hyperhomocysteinemia (HHCY) has been demonstrated to affect cochlear microvasculature as well as cochlear epithelial cells directly, with a resultant alteration of the expression of matrix metalloproteinases (MMPs) and their inhibitors, tissue inhibitors of metalloproteinases (TIMPs). Hence, ascertaining the optimum concentration of MMPs and TIMPs in the cochlea could help to inhibit hearing loss due to HHCY by the administration of appropriate MMP inhibitors, Since infections/inflammations as well as ototoxic antibiotics have a similar mechanism of otic pathology, the cochlear damage they cause could also be similarly prevented.  相似文献   
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A number of studies have shown, counter-intuitively, that skilled adult readers find it difficult to correctly relate phonemes to graphemes in written words. In most adults this is of little consequence. However, teachers are required to show children how to relate phonemes to graphemes when teaching reading. This study investigated whether a brief period of instruction would improve the ability of adults in this task. Results showed a general level of improvement relative to controls. Exposure alone to the task had no effect. Improvement for the instructed group was not very large and there was difficulty relating phonemes to graphemes which had more than one letter. It may be that trainee teachers need instruction to improve knowledge of grapheme phoneme correspondence so that they can pass such knowledge onto young readers.  相似文献   
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Research into sighted children’s reading shows that letter recognition skill predicts phonological awareness skill. Congenitally–blind children do not receive exposure to environmental print and do not generally learn to recognise written letters of the alphabet prior to schooling in Braille. A cross–sectional analysis revealed that blind children with no knowledge of written letters or written words showed no ability at measures of phonological awareness. Blind children with knowledge of written letters and no written words showed much increased phonological awareness scores and blind children with knowledge of written letters and written words scored higher still on phonological awareness measures. It was concluded that letter learning is a major contributor to the development of phonological awareness in blind children. It suggests key similarities in the underlying processes of reading development across two different populations using different modalities to learn to read.  相似文献   
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