The ‘Affective Place-Making’ Practices of Girls at a High School in Cape Town,South Africa

This article focuses on the affective place-making practices of girls at a private high school on the outskirts of Cape Town. The article responds to the question: How do high school girls' affects and social bodies contribute to their place-making practices and to the type of place they make of their school? Our focus is on understanding the affective, emotional, and interactional dimensions that constitute 5 girls' strategic interactions in the out-of-classroom spaces of their school. Drawing on theories of affect, the article is based on a 6-month ethnographic research study at Mount Valley High (pseudonym). We present 3 specific incidents from our data to illustrate each of the key dimensions that we believe relate to the girls' affective place-making practices. We develop the idea that spaces such as schools become places as a result of the interaction between the expressive institutional culture of the school, on the one hand, and the vigorous interaction of the students' engagement with each other in the various spaces of school, on the other. We present the 3 critical incidents to advance a conceptual argument about the link between affect and place-making in the light of the school's expressive culture. We argue that the girls in our study interpret the culture of their school and act in response to its discourses. They go on to make place in highly specific ways by recreating the school as a place through a combination of individual, group and strategic place-making practices, turning the school into a particular place.     

Pre-analytical mysteries: A case of severe hypervitaminosis D and mild hypercalcaemia

We describe a case of severe hypervitaminosis D and mild hypercalcaemia in a 68-year-old woman who presented with fatigue and weight loss. Her 25-hydroxy vitamin D (25OHD) was > 400 nmol/L (50-150) and corrected serum calcium was 2.83 mmol/L (2.1-2.6). Her intact parathyroid hormone (PTH) was 4.9 pmol/L (2.0-9.5). Further investigation revealed an IgM kappa paraprotein, and a bone marrow aspirate confirmed a diagnosis of lymphoplasmacytic lymphoma/Waldenstrom’s macroglobulinemia (LPL/WM). As the vitamin D level was discordant with the patient’s other results and presentation, the presence of an assay interferent was suspected. A 1-in-2 dilution of the sample returned a 25OHD result of 84 nmol/L in keeping with the presence of an interferent. Testing for rheumatoid factor was negative. The sample was treated with an antibody blocking reagent (Scantibodies) and results were not consistent with heterophile antibody interference. The sample was then analysed using liquid chromatography tandem mass spectrometry (LC-MS/MS), which returned a 25OHD result of 82 nmol/L. Testing on an alternative immunoassay platform produced a 25OHD result of 75 nmol/L. Reapeted testing on the original platform following reduction of the monoclonal paraprotein with chemotherapy, returned a result of 64 nmol/L. The patient’s mild hypercalcaemia persisted following resolution of the monoclonal paraprotein, in keeping with a diagnosis of primary hyperparathyroidism. This case highlights the potential for paraproteins to cause assay interference, and the importance of considering interference when results are incongruous with the clinical presentation.