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1.
Sridhar Mishra Devanshi B. Dubey Krachi Agarwal Deval B. Dubey Shweta Verma Nida Shabbir Rashmi Kushwaha D Himanshu Reddy Uma Shankar Singh Wahid Ali 《Indian journal of clinical biochemistry : IJCB》2023,38(2):172
Lymphocyte dysregulation in coronavirus disease-19 (COVID-19) is a major contributing factor linked to disease severity and mortality. Apoptosis results in the accumulation of cell-free DNA (cfDNA) in circulation. COVID-19 has a heterogeneous clinical course. The role of cfDNA levels was studied to assess the severity and outcome of COVID-19 patients and correlated with other laboratory parameters. The current case series included 100 patients with mild COVID-19 (MCOV-19) and 106 patients with severe COVID-19 (SCOV-19). Plasma cfDNA levels were quantified using SYBR green quantitative real-time PCR through amplification of the β-actin gene. CfDNA level was significantly higher in SCOV-19 at 706.7 ng/ml (522.6–1258) as compared to MCOV-19 at 219.8 ng/ml (167.7–299.6). The cfDNA levels were significantly higher in non-survivor than in survivors (p = 0.0001). CfDNA showed a significant correlation with NLR, ferritin, LDH, procalcitonin, and IL-6. The diagnostic sensitivity and specificity of cfDNA in the discrimination of SCOV-19 from MCOV-19 were 90.57% & 80%, respectively. CfDNA showed a sensitivity of 94.74% in the differentiation of non-survivors from survivors. CfDNA levels showed a significant positive correlation with other laboratory and inflammatory markers of COVID-19. CfDNA levels, NLR, and other parameters may be used to stratify and monitor COVID-19 patients and predict mortality. CfDNA may be used to predict COVID-19 severity with higher diagnostic sensitivity. 相似文献
2.
Internationalization of scientific publishing over time: Analysing publishers and fields differences
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The changes in journal internationality in mainstream science were examined using 1,398 journals and 2,557,229 papers during 1991–2014. The authors’ country of affiliation in journals’ papers and references of multinational and national publishers were analysed. The results showed that journals’ papers and references have become more globalized over time. On average, older journals are more international than the newer ones. Although multinational publishers publish more international journals than the national ones do, journals from national publishers have internationalized faster than those from multinationals. The difference between these two groups of publishers is much greater in authoring compared to referencing. For both groups of publishers, the most changes in journal internationality occurred between the fourth and sixth year of indexing in Web of Science. Journals and papers in Humanities journals have the highest rate of increase of internationality although Natural Sciences and Engineering and Technology have the most international papers. Agricultural Sciences has the least international papers; however, these papers cite a wider range of countries’ papers compared to other fields. Journals in Medical and Health Sciences, Natural Sciences, and Agricultural Sciences have the most international references. 相似文献
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Ozcan Karaaslan Ibrahim Diken Gerald Mahoney 《International Journal of Disability, Development & Education》2011,58(4):359-372
The case study was conducted to examine the feasibility of an early intervention curriculum called Responsive Teaching with two five-year-old children from Turkey who had significant developmental delays. This study determined whether Turkish mothers might be successful in learning to become more responsive to their children, and whether this would result in significant improvements in their children’s development. Both dyads received 28 individual parent–child intervention sessions which were conducted over a four-month period of time. Pre-, mid-, and post-assessments indicated improvements in the mothers’ responsiveness to their children and the children’s levels of engagement with their parents. There were also improvements in the children’s language and personal social development. Mothers reported that Responsive Teaching helped them learn to interact more effectively with their children and that this resulted in longer and more enjoyable interactions with them. Results from this investigation are discussed in terms of their implications for providing developmental services to preschool-aged children with disabilities in Turkey. 相似文献
6.
Kocer Omer Dincer Ali 《美中教育评论》2011,(3):257-263
When examined carefully, it is seen that there is not an available and detailed cttrriculum designed for the aim of foreign language teaching with integrated cultural items of the target language in the programs of the schools under authority of the Ministry of Education and Turkish higher education institutions. In recent years, the specialists have an agreement on the issue that foreign language instruction should be carried out by the means of target language's history, literature, geography and also its social characteristics. The idiom "it's raining cats and dogs" can be misinterpreted by a Turkish student without the knowledge of this idiom's story in English history as "Cats and dogs are pouring down from the sky". An important French architectural building "Saint Mary Cathedral, Notre Dame de Paris" can be misunderstood as "Our Parisian Woman" by a student who is unfamiliar with French culture. Both examples show that encountered foreign words and phrases can be misunderstood and mostly these words are perceived and interpreted according to learners' own cultural figures. The aims of this study are to show the significance of culture-based foreign language courses and to make a contribution to the literature by regarding the views of researchers beheving that culture and language are inseparable concepts. In this context, Erzincan University French Language Teaching Department students' opinions on the relation between culture and language learning were received with the application of qualitative structured written response method. Then, document analysis of written comments was evaluated. Consequently, the analysis on the participants' written comments showed that a culture integrated foreign language course can make positive contributions to students' learning, language learning process and learning environment. 相似文献
7.
Amal Alhadabi Said Aldhafri Hussain Alkharusi Ibrahim Al-Harthy Marwa Alrajhi Hafidha AlBarashdi 《Asia Pacific Journal of Education》2019,39(1):133-153
The current study investigated the associations between three maternal and paternal parenting styles, moral intelligence, academic self-efficacy and learning motivation in three serial mediation models. Omani adolescents enrolled in 7th to 11th grades (N = 296) responded to an online survey containing demographic items and scales measuring the variables noted above. Results of Path Analysis indicated that the three models had a good overall fit. In detail, the three paternal styles (authoritative, authoritarian and permissive) had direct associations with moral intelligence and indirect associations with learning motivation. However, only two maternal parenting styles (i.e., authoritative and authoritarian) correlated directly with learning motivation and these two styles did not associate with moral intelligence. All effects were in the hypothesized direction except the effect of authoritative maternal and paternal styles. Moral intelligence had a positive direct correlation with students’ academic self-efficacy and learning motivation. Moral intelligence also mediated the negative associations between three types of fathers’ parenting styles and students’ motivation. Academic self-efficacy had a positive association with students’ motivation. These findings provided useful insights about the various association between external factors (e.g., parenting styles), internal factors (i.e., moral intelligence and self-efficacy) and students’ motivation among adolescents in middle and high schools. 相似文献
8.
Arzu Saka Lale Cerrah Ali Rıza Akdeniz Alipaşa Ayas 《Journal of Science Education and Technology》2006,15(2):192-202
The study was carried out with 175 Turkish students by using drawings at different ages understanding of gene, DNA and chromosome concepts. Students from 8th, 9th, 11th grades and, science and biology student teachers were simply asked to draw the structure of gene, DNA and chromosome in a cell and also to give explanations about these three concepts. Differences in understanding between the age groups were found to be significant for the concepts of gene and DNA. None of the groups exhibit sound understanding and regardless of the age levels, students in all groups had alternative ideas about the three concepts investigated. 相似文献
9.
A systems-based classroom intervention on environmental education was designed for seventh grade students; the results were evaluated to see its impact on the development of systems thinking skills and standard science achievement and whether the systems approach is a more effective way to teach environmental issues that are dynamic and complex. A quasi-experimental methodology was used to compare performances of the participants in various dimensions, including systems thinking skills, competence in dynamic environmental problem solving and success in science achievement tests. The same pre-, post- and delayed tests were used with both the comparison and experimental groups in the same public middle school in Istanbul. Classroom activities designed for the comparison group (N = 20) followed the directives of the Science and Technology Curriculum, while the experimental group (N = 22) covered the same subject matter through activities benefiting from systems tools and representations such as behaviour over time graphs, causal loop diagrams, stock-flow structures and hands-on dynamic modelling. After a one-month systems-based instruction, the experimental group demonstrated significantly better systems thinking and dynamic environmental problem solving skills. Achievement in dynamic problem solving was found to be relatively stable over time. However, standard science achievement did not improve at all. This paper focuses on the quantitative analysis of the results, the weaknesses of the curriculum and educational implications. 相似文献
10.
Modeling of D-STATCOM in distribution systems load flow 总被引:1,自引:0,他引:1
HOSSEINI Mehdi SHAYANFAR Heidar Ali FOTUHI-FIRUZABAD Mahmud 《浙江大学学报(A卷英文版)》2007,8(10):1532-1542
This paper presents modeling of Distribution STATCOM (D-STATCOM) in load flow calculations for the steady- state voltage compensation. An accurate model for D-STATCOM is derived to use in load flow calculations. The rating of this device as well as the direction of required reactive power injection for voltage compensation in the desired value (1 p.u.) is de- rived and discussed analytically and mathematically by the phasor diagram method. Furthermore, an efficient method for node and line identification used in load flow calculations is presented. The validity of the proposed model is examined by using two standard distribution systems consisting of 33 and 69 nodes, respectively. The best location of D-STATCOM for under voltage problem mitigation approach in the distribution networks is determined. The results validate the proposed model for D- STATCOM in large distribution systems. 相似文献