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Working memory training improves children's cognitive performance on untrained tasks; however, little is known about the underlying neural mechanisms. This was investigated in 32 typically developing children aged 10–14 years (19 girls and 13 boys) using a randomized controlled design and multi-modal magnetic resonance imaging (Devon, UK; 2015–2016). Training improved working memory performance and increased intrinsic functional connectivity between the bilateral intraparietal sulci. Furthermore, improvements in working memory were associated with greater recruitment of the left middle frontal gyrus on a complex span task. Repeated engagement of fronto-parietal regions during training may increase their activity and functional connectivity over time, affording greater working memory performance. The plausibility of generalizable cognitive benefits from a neurobiological perspective and implications for neurodevelopmental theory are discussed.  相似文献   
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  • Scientific publication has been a key part of the scientific method since the inception of Philosophical Transactions in 1665.
  • The scientific publications industry has grown exponentially along with science, incorporating technological innovations along the way, and adapting journal processes and practices to changing needs of science as it matured.
  • Of all the technological innovations over more than 300 years, the move to online journals may be the most significant, making open access to content practical for the first time.
  • The open‐access movement is disrupting the economics of journal publishing, which is hoped will make the industry more competitive: the ability of the publications industry to adapt to open access will be a measure of its resilience.
  • The demand for articles published in reputable journals continues to grow as readers trust the credibility of peer reviewed journal articles, and good authors value the prestige of publishing in the best journals.
  • It is difficult to predict what new functionalities may be included in articles of the future or what additional services publishers and editors will provide, but there is every reason to believe that scientific journal articles are here to stay.
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Seventy-nine 3-year olds and their mothers participated in a laboratory-based task to assess maternal hostility. Mothers also reported their behavioral regulation of their child. Seven years later, functional magnetic resonance imaging data were acquired while viewing emotional faces and completing a reward processing task. Maternal hostility predicted more negative amygdala connectivity during exposure to sad relative to neutral faces with frontal and parietal regions as well as more negative left ventral striatal connectivity during monetary gain relative to loss feedback with the right posterior orbital frontal cortex and right inferior frontal gyrus. In contrast, maternal regulation predicted enhanced cingulo-frontal connectivity during monetary gain relative to loss feedback. Results suggest parenting is associated with alterations in emotion and reward processing circuitry 7–8 years later.  相似文献   
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根据中医内科辩证和因时制宜原则 ,对校田径代表队在夏季比赛期间服用活血皇浆前后进行血液动力流变学和血液有形成分参数的比较观察结果表明 ,运动员服液后在脉率 (PR)、每搏量 (SV)、心输出量 (CO)、左心有效泵力 (VPE)和左心能量有效利用率 (EWK )改善的同时 ,出现心肌耗氧量 (HOV)、心肌耗氧指数 (HOI)、心肌血液需要量 (CMBN)、心肌血液灌注量(CMBV)和总周阻 (TPR)、标准周阻 (SPR)、收缩压 (SP)舒张压 (DP)等参数下降 ,呈现机能和能量节省化 ,而血液状态则表现为血容量 (BV)增多 ,全血粘度 (η)和还原血粘度 (ηr)下降 ,切变应力增高 ,血流速度加快 ,有利于维持微循环正常功能。血液有形成分的改变提示 ,血红蛋白 (Hb)红细胞比积 (HCT)和血小板 (PL T)有增高趋势 ;平均红细胞血红蛋白浓度 (MCHC)下降 ,则有可能与 BV相对增多 ,红细胞 (RBC)体积增大有关  相似文献   
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This study examined two levels of media agenda effects on aggregatepublic opinion from different news sources. The effects wereinvestigated immediately and cumulatively. Content analysisdata from the 2000 U.S. presidential election coverage by fournational news organizations were related to the Gallup pre-electionpoll standings of each candidate. Regression analyses foundthat both the salience of a candidate and the salience of theattributes of a candidate cumulatively, but not immediately,influenced his standing in the polls. An analysis of news sourcessupported the finding that the two levels of agenda-settingeffects seemed mostly cumulative rather than immediate. Newsfrom different sources, however, tended to have effects of differentdegrees and sometimes different directions on candidate pollstandings. Cumulative effects of candidate salience on aggregateopinion change were found for non-partisan and neutral newssources—reporters, poll reporting and public documents—whereasthe effects of candidate attribute salience mostly came frompartisan sources—the candidate himself and members ofthe competing political party. Possible political implicationsof these findings are discussed.  相似文献   
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