Poly A RNA status and expression of milli (m) and micro (μ) calpains in skeletal muscle of duchenne muscular dystrophy patients

Poly A RNA status and itsin vitro translation in a rabbit reticulolysate cell free system, were assessed in the skeletal muscle of young boys with Duchenne muscular dystrophy. Compared to normals there is a significant 48% increase in poly A RNA content of dystrophic muscle and its translatability was increased by 56% based on³⁵S methionine incorporation into total protein systhesised. Immunoprecipitation of the translated products with monospecific antibodies showed that there is a 2.6 fold and a 2 fold increase in m and μ calpains respectively. This underlines the importance of both synthetic and degenerative activities in the early pathology in DMD muscle.     

Mentoring Matters: An Exploratory Survey of Educational Leadership Doctoral Students’ Perspectives

There is limited research on quantitative differences between men and women’s experiences in doctoral programs. We aim to fill that gap by sharing findings from a web-based exploratory survey of perceived gender differences on quality mentoring in educational leadership doctoral programs. According to survey results, there is limited statistical significance in terms of gender differences in programmatic supports and scholarly progress. However, women experience feelings of self-doubt due to negative experiences with advising and mentoring, including difficulties making connections to a quality mentor. Furthermore, both female and male participants shared common definitions of what constitutes quality mentorship and believed mentorship was important, but lacking in varying degrees. Finally, all participants agreed that their educational leadership preparation programs should provide additional support in terms of writing and research development. Participants also shared important recommendations for strengthening mentoring experiences as well as future research methods and foci.     

Considering ‘teacher resilience’ from critical discourse and labour process theory perspectives

This article considers the construct of ‘teacher resilience’ from critical discourse and labour process perspectives in order to cast new light on what has been traditionally viewed from a psychological perspective. In this respect, the construct of resilience is placed in the broad political landscape of teachers’ work and the labour process of teaching, within a neoliberal globalised economic paradigm. Importantly, this article argues that any conceptualisations of teacher resilience should be critically appraised and not simply ‘taken for granted’. While the concept of developing ‘teacher resilience’ as a means, for example, of addressing alarmingly high rates of early career teacher attrition may sound like a good idea, it is important to consider the way such constructs can be used to shape and potentially control teacher identity and the nature of teachers’ work.     

“Truth or consequences”: a feminist critical policy analysis of the STEM crisis

STEM education has received significant attention in the USA and is largely fueled by rhetoric suggesting the USA is losing its global competitive edge and that there is a lack of qualified workers available to fill growing STEM jobs. However, a counter discourse is emerging that questions the legitimacy of these claims. In response, we employed feminist critical policy analysis as both a theory and a method to further critique the STEM crisis discourse. We argue that the nature of the current discourse is misleading at worst and incomplete at best and show who is fueling the crisis discourse and who stands to win or lose as a result. We reveal how the crisis discourse draws attention away from the multi-layered complexity of the issue and surface what is missing in the discourse to re-center public attention on protracted problems that still need dismantling.     

Developing a discourse of the postmodern community development professional

This article seeks to promote the generation of a discourse of the postmodern community work professional. A shared discourse will lead, we propose to shared capital. We argue that there is a tension between the modern and postmodern for those of us engaged in the profession of community learning and development (CL&D). We need to value reflexivity which allows the community worker to make sense of multiple discourses and to make the transition from modernism to postmodernism. We need in the CL&D profession to recognise that Marxist principles that we espoused in the 1980s may be enhanced by a new theoretical base that still values change.