The neural correlates of working memory training in typically developing children

Working memory training improves children's cognitive performance on untrained tasks; however, little is known about the underlying neural mechanisms. This was investigated in 32 typically developing children aged 10–14 years (19 girls and 13 boys) using a randomized controlled design and multi-modal magnetic resonance imaging (Devon, UK; 2015–2016). Training improved working memory performance and increased intrinsic functional connectivity between the bilateral intraparietal sulci. Furthermore, improvements in working memory were associated with greater recruitment of the left middle frontal gyrus on a complex span task. Repeated engagement of fronto-parietal regions during training may increase their activity and functional connectivity over time, affording greater working memory performance. The plausibility of generalizable cognitive benefits from a neurobiological perspective and implications for neurodevelopmental theory are discussed.     

在线健康社区用户个人健康信息管理行为特征研究

[目的/意义] 旨在对在线健康社区用户的个人健康信息管理行为特征进行分析，并在此基础上，对"平台-PHIM-健康目标"这一模式中的元素之间的关系进行探讨。[方法/过程] 选择患有红斑狼疮的在线健康社区用户作为调查对象。采用聚类方法对个人健康信息管理行为的总体测度水平不同的群体进行识别；利用单因素方差分析（One-way ANOVA）对不同群组进行比较研究。[结果/结论] 将依托在线健康社区进行的个人健康信息管理行为界定为健康信息发现、健康信息互动和健康信息分享。从数据分析结果来看，首先，在线健康社区的红斑狼疮患者在个人健康信息管理行为水平上存在显著的高低差异。第二，用户所感知到的社会支持与其个人健康信息管理水平存在正相关关系。第三，个人健康信息管理与用户健康目标之间存在正相关关系。本研究为在线健康社区完善其服务方式，促进慢性病人个人健康信息管理水平提高提供合理建议。     

智能时代多语种信息处理技术的创新与发展 ——访中国工程院院士吾守尔·斯拉木教授

吾守尔·斯拉木院士阐述了多语种信息处理技术的发展现状,围绕新兴技术与多语种智能信息处理的结合对教育的影响、民族语言信息化在"一带一路"建设中的特色和优势,以及多语种智能信息处理的产学研一体化发展等方面提出了诸多有价值的建议.吾守尔院士团队开拓了计算机民文信息处理新领域,突破和解决了民文信息处理领域的许多关键理论及核心技术;分析了大数据和人工智能技术在多语种智能信息处理中的应用,研发了智能双语教学系统,有效解决了民族教育发展不均衡、优质教育资源不能充分利用的问题;结合"一带一路"倡议,建设教育信息化"丝绸之路",针对不同沿线国家共建需要开展"多语种+"跨文化教育;分析了人工智能与多语种智能信息化处理相融合的交叉学科对学科建设和人才培养的影响.     

Genetic Polymorphism of Angiotensin II Type 1 Receptors and Their Effect on the Clinical Outcome of Captopril Treatment in Arab Iraqi Patients with Acute Coronary Syndrome (Mid Euphrates)

Genetic variation in the angiotensin II type 1 receptor (AT1R) has an important effect on the outcome of acute coronary syndrome (ACS) initiated treatment with captopril. This study aims to investigate the impact of genetic polymorphism of AT1R (rs5186 and rs275651) on the ACS outcome in Iraqi patients treated with captopril. A total of 250 Iraqi individuals with ACS were included in this case—control study and they were divided into two study groups; Study group 1 included 125 participants who were prescribed captopril, 25 mg twice daily and study group 2 included 125 participants who received no captopril as part of their ACS treatment (control study). The AT1R gene (rs5186) CC genotype was found to be associated with ST-elevation myocardial infarction (STEMI) (Odd’s ratio (O.R) = 1.2, P = 0.7), while AC was associated with Non-ST-elevation myocardial infarction (NSTEMI) and unstable angina (UA) (O.R = 1.2, P = 0.8). AC genotype is more prone to have Percutaneous coronary intervention (PCI) after ACS attack (O.R = 1.2, P = 0.6). CC genotype had a risk to get less improvement (O.R = 1.6, P = 0.5), so might require higher doses of captopril during acute coronary insult. The AT1R gene (rs275651) AA genotype was associated with UA (O.R = 1.3, P = 0.9). AA and AT genotypes were more prone to have PCI after ACS attack (O.R = 3.9 P = 0.2, O.R = 3.5, P = 0.3 respectively) and thus requiring higher doses of captopril. We conclude that the AT1R rs5186, rs275651 genetic polymorphisms might partially affect the clinical outcome of ACS patients treated with captopril and might have captopril resistance which requires higher doses.     

Digital Module 16: Longitudinal Data Analysis

In this digital ITEMS module, Dr. Jeffrey Harring and Ms. Tessa Johnson introduce the linear mixed effects (LME) model as a flexible general framework for simultaneously modeling continuous repeated measures data with a scientifically defensible function that adequately summarizes both individual change as well as the average response. The module begins with a nontechnical overview of longitudinal data analyses drawing distinctions with cross-sectional analyses in terms of research questions to be addressed. Nuances of longitudinal designs, timing of measurements, and the real possibility of missing data are then discussed. The three interconnected components of the LME model—(1) a model for individual and mean response profiles, (2) a model to characterize the covariation among the time-specific residuals, and (3) a set of models that summarize the extent that individual coefficients vary—are discussed in the context of the set of activities comprising an analysis. Finally, they demonstrate how to estimate the linear mixed effects model within an open-source environment (R). The digital module contains sample R code, diagnostic quiz questions, hands-on activities in R, curated resources, and a glossary.     

中国共产党领导下的大连福岛纺织株式会社工人大罢工

1926年4月27日,因无法忍受日本资本家的残酷压榨和剥削,大连福岛纺织株式会社1000余名工人举行了声势浩大的罢工。罢工过程中,日本资本家采取了种种惨无人道的压迫手段逼迫工人复工。在中国共产党的领导下,工人们团结一致,坚定信念,最终取得罢工斗争的胜利,充分展示了中国工人阶级的强大力量,而中国共产党的领导对此次罢工的胜利起到了决定性的作用。     

Food (in)security communication: a Journal of Applied Communication Research forum addressing current challenges and future possibilities

ABSTRACT

This forum brings together food, (in)security, and communication. The authors participating in this forum center communication as both process and tool for understanding, mitigating, and making meaning of food (in)security. The nine authors together discuss the role of communication in food (in)security, the central challenges for scholars and practitioners working on food (in)security, and the creative possibilities and impacts influencing the future of food (in)security. The forum produces a call for applied scholars to re-imagine communication frameworks in order to make meaningful differences in their communities.     

电子书用户使用意愿影响模型构建与实证

[目的/意义] 探究用户使用电子书意愿的影响因素，以有助于电子书产业走出缓慢的发展困境。[方法/过程] 以UTAUT2、使用满足理论为基础，从需求满足和外部情景因素两个层面构建影响因素模型，并将需求满足细化为内容需求、社交互动需求和休闲娱乐需求3个测量变量。采用问卷调查方法收集有效样本1 013份，使用AMOS21软件对模型进行验证。[结果/结论] 研究发现，需求满足、阅读习惯、价格价值、社会影响对使用意愿有正向影响作用，而激励措施对使用意愿有负向影响作用，努力期望对使用意愿的影响不显著，并依据研究结果提出促进电子书产业发展的建议。