The neural correlates of working memory training in typically developing children

Working memory training improves children's cognitive performance on untrained tasks; however, little is known about the underlying neural mechanisms. This was investigated in 32 typically developing children aged 10–14 years (19 girls and 13 boys) using a randomized controlled design and multi-modal magnetic resonance imaging (Devon, UK; 2015–2016). Training improved working memory performance and increased intrinsic functional connectivity between the bilateral intraparietal sulci. Furthermore, improvements in working memory were associated with greater recruitment of the left middle frontal gyrus on a complex span task. Repeated engagement of fronto-parietal regions during training may increase their activity and functional connectivity over time, affording greater working memory performance. The plausibility of generalizable cognitive benefits from a neurobiological perspective and implications for neurodevelopmental theory are discussed.     

Between Policy and Practice: Archival Descriptions,Digital Returns and a Place for Coalescing Narratives

ABSTRACT

The Strathfieldsaye Estate collection at the University of Melbourne Archives is discussed in relation to recognising, protecting and reclaiming Koori (First Peoples of southeast Australia) heritage. The settler collection includes early 1900s photographs of Koori people within two distinct albums – a family album that includes a series of studio portraits of Koori adults and children, and an album depicting Koori families on Ramahyuck Aboriginal Mission Station. In the past, these albums have been defined by, and limited to, traditional archiving practices excluding Koori interpretation, authorship and social context. Restoring Koori ownership and authorship of intangible heritage plays a large part in consolidating ancestor photographs with Koori perspectives of identity and culture.     

Carnosine in health and disease

Abstract

Carnosine was originally discovered in skeletal muscle, where it exists in larger amounts than in other tissues. The majority of research into the physiological roles of carnosine have been conducted on skeletal muscle. Given this and the potential for muscle carnosine content to be increased with supplementation, there is now a large body of research examining the ergogenic effects (or otherwise) of carnosine. More recent research, however, points towards a potential for carnosine to exert a wider range of physiological effects in other tissues, including the brain, heart, pancreas, kidney and cancer cells. Taken together, this is suggestive of a potential for carnosine to have therapeutic benefits in health and disease, although this is by no means without complication. Herein, we will provide a review of the current literature relating to the potential therapeutic effects of carnosine in health and disease.     

Managing Health Care in Oregon: The Search for a Civic Bioethics

Managed health care deliberations in Oregon point to a "civic bioethics" model to resolve allocation issues through publicly articulated community values and priorities that influence legislative action. Communication practices in the Oregon experiment provide data to develop an evaluative framework to assess public moral deliberation in value-laden contexts such as health care distribution. The Oregon experience also points to dialogical virtues to heighten citizens' ethical sensibilities and political will, discursive tools to inform ethical communication practices in a civic bioethics model.     

Students Demonstrating Persistent Low Response to Reading Intervention: Three Case Studies

Three students with severe reading disabilities participated in a 3‐year intervention provided by trained tutors from first grade through third grade (175–231 hours). All three students demonstrated very low response to initial levels of intervention and were provided adjusted intensive intervention in an attempt to remedy their low response to instruction. Findings revealed that two of the three students realized limited growth and did not accelerate progress toward reducing the gap between their performance and the expected grade level performance. One student accelerated growth considerably during third grade and made accelerated progress toward grade level expectations. Information on intervention implementation and student progress as well as implications for practice and further research are discussed.