信息化对体育产业发展的作用分析

本文重点分析了体育产业发展与经济增长的关系,信息产业与体育产业发展的相关关系以及体育产业信息化对体育产业发展的作用。指出了体育产业信息化是促进体育产业发展的必然之路。     

Migration and vascular lumen formation of endothelial cells in cancer cell spheroids of various sizes

We developed a microfluidic device to culture cellular spheroids of controlled sizes and suitable for live cell imaging by selective plane illumination microscopy (SPIM). We cocultured human umbilical vein endothelial cells (HUVECs) within the spheroids formed by hepatocellular carcinoma cells, and studied the distributions of the HUVECs over time. We observed that the migration of HUVECs depended on the size of spheroids. In the spheroids of ∼200 μm diameters, HUVECs migrated outwards to the edges within 48 h; while in the spheroids of ∼250 μm diameters, there was no outward migration of the HUVECs up to 72 h. In addition, we studied the effects of pro-angiogenic factors, namely, vascular endothelial growth factor (VEGF) and fibroblast growth factor (β-FGF), on the migration of HUVECs in the carcinoma cell spheroid. The outward migration of HUVECs in 200 μm spheroids was hindered by the treatment with VEGF and β-FGF. Moreover, some of the HUVECs formed hollow lumen within 72 h under VEGF and β-FGF treatment. The combination of SPIM and microfluidic devices gives high resolution in both spatial and temporal domains. The observation of HUVECs in spheroids provides us insight on tumor vascularization, an ideal disease model for drug screening and fundamental studies.     

The impact of peer competition and collaboration on gamified learning performance in educational settings: a Meta-analytical study

Education and Information Technologies - This study is a meta-analytical study that examines the effectiveness of gamification in learning performance in educational settings (n = 29;...     

国内知识服务评价应用进展

【目的/意义】知识服务评价有利于服务机构发现自身问题,提高核心竞争力,迎合市场需求,创造社会效 益。【方法/过程】运用文献计量法和内容分析法,选取中国知网、万方学位论文及期刊论文库、维普期刊论文库的论 文,介绍了知识服务评价内涵、核心内容和研究框架,根据评价能力、绩效、满意度三类目的、所用评价方法及应用 领域分类阐述了评价结论及优化建议,揭示了国内知识服务评价应用进展。【结果/结论】结果表明,我国知识服务 评价领域集中于高校、图书馆、科技信息机构,评价方法主要为层次分析法、模糊综合评价法,存在对知识服务重要 性认识不足、评价体系不完善等问题,可从服务主客体、基础设施、知识资源、服务流程、服务方式、服务成果六方面 优化,指出当前评价存在问题,并提出改进建议。