The neural correlates of working memory training in typically developing children

Working memory training improves children's cognitive performance on untrained tasks; however, little is known about the underlying neural mechanisms. This was investigated in 32 typically developing children aged 10–14 years (19 girls and 13 boys) using a randomized controlled design and multi-modal magnetic resonance imaging (Devon, UK; 2015–2016). Training improved working memory performance and increased intrinsic functional connectivity between the bilateral intraparietal sulci. Furthermore, improvements in working memory were associated with greater recruitment of the left middle frontal gyrus on a complex span task. Repeated engagement of fronto-parietal regions during training may increase their activity and functional connectivity over time, affording greater working memory performance. The plausibility of generalizable cognitive benefits from a neurobiological perspective and implications for neurodevelopmental theory are discussed.     

Carnosine in health and disease

Abstract

Carnosine was originally discovered in skeletal muscle, where it exists in larger amounts than in other tissues. The majority of research into the physiological roles of carnosine have been conducted on skeletal muscle. Given this and the potential for muscle carnosine content to be increased with supplementation, there is now a large body of research examining the ergogenic effects (or otherwise) of carnosine. More recent research, however, points towards a potential for carnosine to exert a wider range of physiological effects in other tissues, including the brain, heart, pancreas, kidney and cancer cells. Taken together, this is suggestive of a potential for carnosine to have therapeutic benefits in health and disease, although this is by no means without complication. Herein, we will provide a review of the current literature relating to the potential therapeutic effects of carnosine in health and disease.     

Gender and textbooks: Women writers of elementary readers, 1880–1950

Between 1880 and 1950, the role of women as authors of elementary readers flowered and faded. From 1880 to 1915, female authorship dominated. Over the next fifteen years female authorship withstood the challenge of the scientific movement in education. Women’s role as solo authors declined, however, during the Depression, World War II and the postwar years. These changes are explained by the deteriorating environment for female professionalism, changes in the concept of reading expertise, the expanded role of publishers in textbook development, and the differences between men and women in opportunities for graduate study. E. Jennifer is Monaghan a professor in the Department of Educational Services, Brooklyn College of the City University of New York. She is the founder of the History of Reading Special Interest Group of the International Reading Association and author ofA Common Heritage: Noah Webster’s Blue-Back Speller.