A General Evaluation Framework for Topical Crawlers

Topical crawlers are becoming important tools to support applications such as specialized Web portals, online searching, and competitive intelligence. As the Web mining field matures, the disparate crawling strategies proposed in the literature will have to be evaluated and compared on common tasks through well-defined performance measures. This paper presents a general framework to evaluate topical crawlers. We identify a class of tasks that model crawling applications of different nature and difficulty. We then introduce a set of performance measures for fair comparative evaluations of crawlers along several dimensions including generalized notions of precision, recall, and efficiency that are appropriate and practical for the Web. The framework relies on independent relevance judgements compiled by human editors and available from public directories. Two sources of evidence are proposed to assess crawled pages, capturing different relevance criteria. Finally we introduce a set of topic characterizations to analyze the variability in crawling effectiveness across topics. The proposed evaluation framework synthesizes a number of methodologies in the topical crawlers literature and many lessons learned from several studies conducted by our group. The general framework is described in detail and then illustrated in practice by a case study that evaluates four public crawling algorithms. We found that the proposed framework is effective at evaluating, comparing, differentiating and interpreting the performance of the four crawlers. For example, we found the IS crawler to be most sensitive to the popularity of topics.Partially supported by National Science Foundation CAREER grant No. IIS-0133124/0348940.     

Effect of herbal drug on serum lipid profile in albino rabbits

Abana, a herbal preparation of Himalaya Drug Co. significantly increases HDL—cholesterol and lowers LDL—cholesterol. Moreover, it antagonises the HDL lowering effect of metoprolol.     

System-level simulation of liquid filling in microfluidic chips

Liquid filling in microfluidic channels is a complex process that depends on a variety of geometric, operating, and material parameters such as microchannel geometry, flow velocity∕pressure, liquid surface tension, and contact angle of channel surface. Accurate analysis of the filling process can provide key insights into the filling time, air bubble trapping, and dead zone formation, and help evaluate trade-offs among the various design parameters and lead to optimal chip design. However, efficient modeling of liquid filling in complex microfluidic networks continues to be a significant challenge. High-fidelity computational methods, such as the volume of fluid method, are prohibitively expensive from a computational standpoint. Analytical models, on the other hand, are primarily applicable to idealized geometries and, hence, are unable to accurately capture chip level behavior of complex microfluidic systems. This paper presents a parametrized dynamic model for the system-level analysis of liquid filling in three-dimensional (3D) microfluidic networks. In our approach, a complex microfluidic network is deconstructed into a set of commonly used components, such as reservoirs, microchannels, and junctions. The components are then assembled according to their spatial layout and operating rationale to achieve a rapid system-level model. A dynamic model based on the transient momentum equation is developed to track the liquid front in the microchannels. The principle of mass conservation at the junction is used to link the fluidic parameters in the microchannels emanating from the junction. Assembly of these component models yields a set of differential and algebraic equations, which upon integration provides temporal information of the liquid filling process, particularly liquid front propagation (i.e., the arrival time). The models are used to simulate the transient liquid filling process in a variety of microfluidic constructs and in a multiplexer, representing a complex microfluidic network. The accuracy (relative error less than 7%) and orders-of-magnitude speedup (30 000X–4 000 000X) of our system-level models are verified by comparison against 3D high-fidelity numerical studies. Our findings clearly establish the utility of our models and simulation methodology for fast, reliable analysis of liquid filling to guide the design optimization of complex microfluidic networks.     

Influence of alcoholic extract of whole fruit of trichosanthes dioica on blood sugar,serum lipids,lipoproteins and faecal sterols in normal albino rabbits

Effect of oral administration of 2 ml per day of suspension (in water) of alcoholic extract of whole fruit of Trichosanthes dioica (2%) (=100 g fresh wt.=7 g dry wt.=1/15 g of alcoholic extract) with the help of catheter alongwith basal diet for four weeks have been studied in the normal albino rabbits. It was observed that this extract lowered the blood sugar, total cholesterol, low density lipoprotein cholesterol and triglyceride levels, and increased the high density lipoprotein cholesterol, phospholipid and faecal sterol levels. Such effects are manifested from the very first week of feeding and are statistically significant.