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The present study aims to assess comorbidity of posttraumatic stress disorder (PTSD) in anxiety and depressive disorders and to determine whether childhood trauma types and other putative independent risk factors for comorbid PTSD are unique to PTSD or shared with anxiety and depressive disorders. The sample of 2402 adults aged 18–65 included healthy controls, persons with a prior history of affective disorders, and persons with a current affective disorder. These individuals were assessed at baseline (T0) and 2 (T2) and 4 years (T4) later. At each wave, DSM-IV-TR based anxiety and depressive disorder, neuroticism, extraversion, and symptom severity were assessed. Childhood trauma was measured at T0 with an interview and at T4 with a questionnaire, and PTSD was measured with a standardized interview at T4. Prevalence of 5-year recency PTSD among anxiety and depressive disorders was 9.2%, and comorbidity, in particular with major depression, was high (84.4%). Comorbidity was associated with female gender, all types of childhood trauma, neuroticism, (low) extraversion, and symptom severity. Multivariable significant risk factors (i.e., female gender and child sexual and physical abuse) were shared among anxiety and depressive disorders. Our results support a shared vulnerability model for comorbidity of anxiety and depressive disorders with PTSD. Routine assessment of PTSD in patients with anxiety and depressive disorders seems warranted.  相似文献   
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The objective of this paper is to balance two major conceptual tendencies in science policy studies, continuity and discontinuity theory. While the latter argue for fundamental and distinct changes in science policy in the late 20th century, continuity theorists show how changes do occur but not as abrupt and fundamental as discontinuity theorists suggests. As a point of departure, we will elaborate a typology of scientific governance developed by Hagendijk and Irwin (2006) and apply it to new empirical material. This makes possible a contextualization of the governance of science related to the codification of the “third assignment” of the Swedish higher education law of 1977. The law defined the relation between university science and Swedish citizens as a dissemination project, and did so despite that several earlier initiatives actually went well beyond such a narrow conceptualisation. Our material reveals continuous interactive and rival arrangements linking the state, public authorities, the universities and private industrial enterprises. We show how different but coexisting modes of governance of science existed in Sweden during the 20th century, in clear contrast with the picture promoted by discontinuity theorists. A close study of the historical development suggests that there were several periods of layered governance when interactions and dynamics associated with continuity as well as discontinuity theories were prevalent. In addition, we conclude that the typology of governance applied in the present paper is fruitful for carrying out historical analyses of the kind embarked upon in spite of certain methodological shortcomings.  相似文献   
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Elzinga  Aant 《Minerva》2012,50(3):277-305
When the journal Minerva was founded in 1962, science and higher educational issues were high on the agenda, lending impetus to the interdisciplinary field of “Science Studies” qua “Science Policy Studies.” As government expenditures for promoting various branches of science increased dramatically on both sides of the East-West Cold War divide, some common issues regarding research management also emerged and with it an interest in closer academic interaction in the areas of history and policy of science. Through a close reading of many early issues of Minerva but also of its later competitor journal Science Studies (now called Social Studies of Science) the paper traces the initial optimism of an academically based Science Studies dialogue across the Cold War divide and the creation in 1971 of the International Commission for Science Policy Studies as a bridging forum, one that Minerva strangely chose to ignore. In this light, attention is drawn to aspects of the often forgotten history of Science Studies in the former Soviet Union and the Eastern European block. Reviewed also are several early discussions that are still relevant today: e.g., regarding differing concepts of Big Science, science and democracy, autonomy in higher education and what conditions are necessary to sustain academic freedom and scientific integrity (some of Edward Shils’ primary concerns). Finally, it is noted how the question of quantitative methods to measure scientific productivity lay at the heart of a “Science of Science” movement of the 1960s has re-emerged in a new form integral to the notion of a “Science of Science Policy.”  相似文献   
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Analytical and computational methods are presented for synthesising four-bar linkage mechanisms for recreating specific point trajectories from cyclic two-dimensional locomotion type sports movements. Specifically, Grashof path generation four-bar linkage mechanisms are synthesised for three precision points using linear analytical methods. The resulting linkages are further refined through computational optimisation and filtering methods to increase the path following accuracy. These linkages were able to follow accurately selected body points of cyclic two-dimensional locomotion movements which is demonstrated for the ankle marker during running motion. These linkage synthesis methods can be applied to the design of athletic training and rehabilitation equipment.  相似文献   
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Swimming     
Abstract

The effect on drag of a Speedo Fast‐skin suit compared to a conventional suit was studied in 13 subjects (6 males, 7 females) swimming at different velocities between 1.0 and 2.0 m?s‐1. The active drag force was directly measured during front crawl swimming using a system of underwater push‐off pads instrumented with a force transducer (MAD system). For a range of swimming speeds (1.1, 1.3, 1.5 and 1.7 m?s‐1), drag values were estimated. On a group level, a statistically non‐significant drag reduction effect of 2% was observed for the Fast‐skin suit (p = 0.31). Therefore, the 7.5% reduction in drag claimed by the swimwear manufacturer was not corroborated.  相似文献   
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The effect on drag of a Speedo Fast-skin suit compared to a conventional suit was studied in 13 subjects (6 males, 7 females) swimming at different velocities between 1.0 and 2.0 m.s-1. The active drag force was directly measured during front crawl swimming using a system of underwater push-off pads instrumented with a force transducer (MAD system). For a range of swimming speeds (1.1, 1.3, 1.5 and 1.7 m.s-1), drag values were estimated. On a group level, a statistically non-significant drag reduction effect of 2% was observed for the Fast-skin suit (p = 0.31). Therefore, the 7.5% reduction in drag claimed by the swimwear manufacturer was not corroborated.  相似文献   
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